CX-6258 HCl

Catalog No.: A14275

Pan-PIM kinase inhibitor

CX-6258 HCl

CX-6258 HCl Chemical Structure

CAS NO. 1353859-00-3

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $110.00

Special Price $88.00

10 mg

Regular Price: $180.00

Special Price $144.00

25 mg

Regular Price: $400.00

Special Price $320.00

10mM * 1mL in DMSO
$169.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.
Targets
Pim1 Pim3 Pim2
5 nM16 nM25 nM
In vitro DMSO 57 mg/mL heating (114.36 mM)
Water 89 mg/mL heating (178.57 mM)
Ethanol 1 mg/mL heating (2.0 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.32 mL 200.64 mL
0.5 mM 4.01 mL 20.06 mL 40.13 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14275
Actions Inhibitor
M. Wt 498.4
Formula C26H24ClN3O3.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1353859-00-3
Synonyms CX6258
SMILES CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)/C=C/4\C5=C(C=CC(=C5)Cl)NC4=O.Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy CX-6258 HCl | CX-6258 HCl Supplier | purchase CX-6258 HCl | CX-6258 HCl cost | CX-6258 HCl manufacturer | order CX-6258 HCl | CX-6258 HCl distributor | buy 1353859-00-3| 1353859-00-3 Supplier | purchase 1353859-00-3 | 1353859-00-3 cost | 1353859-00-3 manufacturer | order 1353859-00-3 | 1353859-00-3 distributor
Rewards