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- Ke Chen, .et al. Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma, Cancer Commun (Lond), 2021, Apr; 41(4): 316-332 PMID: 33591636
- Zhiyuan Qin, .et al. miR-224-5p Contained in Urinary Extracellular Vesicles Regulates PD-L1 Expression by Inhibiting Cyclin D1 in Renal Cell Carcinoma Cells, Cancers (Basel), 2021, Feb 4;13(4):618 PMID: 33557163
- Hua Xu, .et al. Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation, Cancers (Basel), 2020, Apr; 12(4): 831 PMID: 32235588
Biological Activity
Cycloheximide (also known as actidione) is used as an selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. by binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi.
| In vitro | DMSO | 48 mg/mL (170.61 mM) | |
| Water | 13 mg/mL (46.2 mM) | ||
| Ethanol | 48 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.54 mL | 177.68 mL | 355.37 mL |
| 0.5 mM | 7.11 mL | 35.54 mL | 71.07 mL |
| 1 mM | 3.55 mL | 17.77 mL | 35.54 mL |
| 5 mM | 0.71 mL | 3.55 mL | 7.11 mL |
*The above data is based on the productmolecular weight 281.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10036 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 66-81-9 |
| Formula | C15H23NO4 |
| M. Wt | 281.4 |
| Purity | >98% |
| SMILES | C[[email protected]]1C[[email protected]@H](C(=O)[[email protected]@H](C1)[[email protected]@H](CC2CC(=O)NC(=O)C2)O)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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