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|Storage||at -20°C 3 years Powder|
|Synonyms||Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,|
|SMILES code||CC[[email protected]]1C(=O)N(CC(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N1)[[email protected]@H]([[email protected]](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C|
|Chemical Name||(E)-14,17,26,32-tetrabutyl-5-ethyl-8-(1-hydroxy-2-methylhex-4-enyl) -1,3,9,12,15,18,20,23,27-nonamethyl-11,29-dipropyl-1,3,6,9,12,15,18,21,24,27,30- undecaazacyclodotriacontan-2,4,7,10,13,16,19,22,25,28,31-undecaone|
|Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.|
|Solubility (25°C) *||In vitro||DMSO||100 mg/mL (83.15 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||100 mg/mL (83.15 mM)|
|In vivo||0.5% methylcellulose/0.2% Tween 80||11 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||8.32 mL||41.58 mL||83.15mL|
|0.5 mM||1.66 mL||8.32 mL||16.63 mL|
|1 mM||0.83 mL||4.16 mL||8.32 mL|
|5 mM||0.17 mL||0.83 mL||1.66 mL|
*The above data is based on the productmolecular weight 1202.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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