Cyclosporin A

Catalog No.: A10260

Cyclosporin A Chemical Structure

CAS NO. 59865-13-3

Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.

Availability: In stock

Package Price Qty
25 mg
100 mg
200 mg
10mM * 1mL in DMSO

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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Cyclosporin A , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.
calcineurin (Cell-free assay)
7 nM
In vitro (25°C) DMSO 100 mg/mL (83.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (83.15 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.32 mL 41.58 mL 83.15 mL
0.5 mM 1.66 mL 8.32 mL 16.63 mL
1 mM 0.83 mL 4.16 mL 8.32 mL
5 mM 0.17 mL 0.83 mL 1.66 mL

*The above data is based on the productmolecular weight 1202.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10260
M. Wt 1202.6
Formula C62H111N11O12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 59865-13-3
Synonyms Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
SMILES CC[[email protected]]1C(=O)N(CC(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N1)[[email protected]@H]([[email protected]](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

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