Cyclosporin A

Name: Cyclosporin A
SKU: A10260
Price: 30 USD
Rating: 5 (3 reviews)

Catalog No.: A10260

Adooq's Cyclosporin A has been cited by 3 publications

Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.

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Important Notice: For research use only. We do not sell to patients.

WARNING: Attention California Residents: This product can expose you to chemicals including Cyclosporin A , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Cyclosporin A has been cited by 3 publications

X Jia, .et al. , J Hazard Mater, 2020, Jun 4;399:123034 PMID: 32544768

Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319

Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467

Biological Activity

Discription

Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.

Targets

Target	Value

Chemical Information

Catalog Num	A10260
Formula	C62H111N11O12
Molecular Weight	1202.6
CAS Number	59865-13-3
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Synonyms	Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	Warmed: 99 mg/mL (82.32 mM)
	Water	Insoluble
	Ethanol	Warmed: 99 mg/mL (82.32 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.32 mL	41.58 mL	83.15 mL
0.5 mM	1.66 mL	8.32 mL	16.63 mL
1 mM	0.83 mL	4.16 mL	8.32 mL
5 mM	0.17 mL	0.83 mL	1.66 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
Cyclosporine 25mg	$30.00	In stock
Cyclosporine 100mg	$55.00	In stock
Cyclosporine 200mg	$75.00	In stock
*Cyclosporin A 10mM 1mL in DMSO**	$73.00	In stock