DBCO-Val-Cit-PAB-MMAE is an ADC drug-linker conjugate designed for the synthesis of antibody-drug conjugates (ADCs). It incorporates the tubulin inhibitor MMAE, which acts as a cytotoxic agent targeting rapidly dividing cells. The DBCO-Val-Cit-PAB linker features an electrophilic group, facilitating stable conjugation to antibodies and enhancing the therapeutic efficacy of ADCs in cancer research applications.
DBCO-Val-Cit-PAB-MMAE is an ADC drug-linker conjugate designed for the synthesis of antibody-drug conjugates (ADCs). It incorporates the tubulin inhibitor MMAE, which acts as a cytotoxic agent targeting rapidly dividing cells. The DBCO-Val-Cit-PAB linker features an electrophilic group, facilitating stable conjugation to antibodies and enhancing the therapeutic efficacy of ADCs in cancer research applications.
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