DBCO-Val-Cit-PABC-PNP is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). This compound features a DBCO moiety that participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. Its unique structure enables precise conjugation and controlled release of cytotoxic agents, making it essential for advancing ADC research and therapeutic development.
DBCO-Val-Cit-PABC-PNP is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). This compound features a DBCO moiety that participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. Its unique structure enables precise conjugation and controlled release of cytotoxic agents, making it essential for advancing ADC research and therapeutic development.
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