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DC_517

Catalog No.: A57698
DNA Methyltransferase Inhibitor
DC_517 is a selective inhibitor of DNA methyltransferase 1 (DNMT1), exhibiting an IC50 of 1.7 μM and a Kd of 0.91 μM. This compound effectively modulates DNA methylation patterns, making it a valuable tool for studies related to epigenetic regulation, gene expression, and cancer research. Research applications include exploring the roles of DNMT1 in cellular processes and evaluating potential therapeutic strategies for diseases associated with abnormal DNA methylation.
DC_517 500017-70-9 DNA Methyltransferase Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$95.00
In stock
2mg
$160.00
In stock
5mg
$195.00
In stock
10mg
$335.00
In stock
25mg
$710.00
In stock
50mg
$1,095.00
In stock
100mg
$1,655.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDC_517 is a selective inhibitor of DNA methyltransferase 1 (DNMT1), exhibiting an IC50 of 1.7 μM and a Kd of 0.91 μM. This compound effectively modulates DNA methylation patterns, making it a valuable tool for studies related to epigenetic regulation, gene expression, and cancer research. Research applications include exploring the roles of DNMT1 in cellular processes and evaluating potential therapeutic strategies for diseases associated with abnormal DNA methylation.
Product Information
Catalog NumA57698
FormulaC33H35N3O2
Molecular Weight505.65
CAS Number500017-70-9
SMILESOC(CNC(C)C)COC(CN1C(C=CC=C2)=C2C3=C1C=CC=C3)CN(C4=CC=CC=C45)C6=C5C=CC=C6
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Epigenetics > DNA Methyltransferases