Deacetoxyvinzolidine is a bis-indole derivative that functions as an anti-microtubular agent by disrupting microtubule assembly. It demonstrates a strong affinity for bovine purified brain tubulin, with a Kd of 3 μM, effectively inhibiting microtubule formation at concentrations as low as 10 nM. Its significant anti-tumoral properties make it a valuable tool for research, particularly in the investigation of leukemia and related malignancies.
Deacetoxyvinzolidine is a bis-indole derivative that functions as an anti-microtubular agent by disrupting microtubule assembly. It demonstrates a strong affinity for bovine purified brain tubulin, with a Kd of 3 μM, effectively inhibiting microtubule formation at concentrations as low as 10 nM. Its significant anti-tumoral properties make it a valuable tool for research, particularly in the investigation of leukemia and related malignancies.
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