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Demethyl bleomycin A2

Catalog No.: A46902
Antibiotic
Demethyl bleomycin A2 is a congener of the antibiotic Bleomycin, exhibiting strong DNA cleavage activity. It is noted for its insensitivity to 5-Methylcytidine, making it a valuable tool for research in nucleic acid interactions and cellular response mechanisms. This compound is suited for studies in cancer therapeutics and molecular biology, aiding in the exploration of DNA-targeting strategies.
Demethyl bleomycin A2 41089-03-6 Antibiotic
Grouped product items
Size Price Stock Qty
1mg
$1,070.00
In stock
5mg
$4,780.00
In stock
10mg
$9,095.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDemethyl bleomycin A2 is a congener of the antibiotic Bleomycin, exhibiting strong DNA cleavage activity. It is noted for its insensitivity to 5-Methylcytidine, making it a valuable tool for research in nucleic acid interactions and cellular response mechanisms. This compound is suited for studies in cancer therapeutics and molecular biology, aiding in the exploration of DNA-targeting strategies.
Product Information
Catalog NumA46902
FormulaC54H81N17O21S3
Molecular Weight1400.52
CAS Number41089-03-6
SMILESO=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCSC)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Microbiology > Antifection > Antibiotic