Biological Activity
Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.08 mL | 80.41 mL | 160.82 mL |
0.5 mM | 3.22 mL | 16.08 mL | 32.16 mL |
1 mM | 1.61 mL | 8.04 mL | 16.08 mL |
5 mM | 0.32 mL | 1.61 mL | 3.22 mL |
*The above data is based on the productmolecular weight 621.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18384 |
---|---|
M. Wt | 621.81 |
Formula | C32H55N5O7 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2503-26-6 |
SMILES | O=C(N[[email protected]]([[email protected]@H](C)CC)(C)C(N(C)[[email protected]@H](C(C)C)C(N(C)[[email protected]@H](C)C(NCC1)=O)=O)=O)[[email protected]@](CCC2)(C)N2C([[email protected]@H](CC(C)C)OC1=O)=O |
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