Desvenlafaxine succinate is the succinate salt form of the primary active metabolite of Venlafaxine, serving as a selective inhibitor of serotonin and norepinephrine reuptake. It exhibits IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET), offering significant potential in modulating neurotransmitter levels. Additionally, Desvenlafaxine succinate demonstrates modest binding affinity at the human dopamine transporter, with 62% inhibition observed at a concentration of 100 μM. This compound is valuable for research in neuropsychiatric conditions and the study of antidepressant mechanisms.
Desvenlafaxine succinate is the succinate salt form of the primary active metabolite of Venlafaxine, serving as a selective inhibitor of serotonin and norepinephrine reuptake. It exhibits IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET), offering significant potential in modulating neurotransmitter levels. Additionally, Desvenlafaxine succinate demonstrates modest binding affinity at the human dopamine transporter, with 62% inhibition observed at a concentration of 100 μM. This compound is valuable for research in neuropsychiatric conditions and the study of antidepressant mechanisms.
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