diABZI-Mal is a STING agonist featuring a maleimide moiety that facilitates the synthesis of conjugates. It effectively activates the cGAS-STING pathway, leading to the production of type I interferons and promoting the maturation of dendritic cells. Additionally, diABZI-Mal enhances CD8+ T cell responses and has demonstrated the ability to inhibit tumor growth, making it a valuable tool in cancer immunotherapy research.
diABZI-Mal is a STING agonist featuring a maleimide moiety that facilitates the synthesis of conjugates. It effectively activates the cGAS-STING pathway, leading to the production of type I interferons and promoting the maturation of dendritic cells. Additionally, diABZI-Mal enhances CD8+ T cell responses and has demonstrated the ability to inhibit tumor growth, making it a valuable tool in cancer immunotherapy research.
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