Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, thereby facilitating various biochemical applications in research. -
Purine Nucleoside Analog
2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analog that primarily targets DNA synthesis. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. Its application in research contributes to the understanding of cancer biology and the development of therapeutic strategies for lymphoid malignancies. -
Norovirus Inhibitor
CMX-521 is a nucleoside analog that functions as a potent inhibitor of the RNA-dependent RNA polymerase (RdRp) of norovirus. This compound effectively suppresses both murine norovirus (MNV) and human norovirus, making it a valuable tool for research into norovirus infections. Its inhibitory properties are essential for studies focused on antiviral development and mechanisms of norovirus replication. -
Purine Nucleoside Analog
2-Amino-6-methylthio-9-(β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exerts its biological activity primarily through the inhibition of DNA synthesis. This compound demonstrates significant antitumor activity against indolent lymphoid malignancies, making it a valuable tool for cancer research. Its mechanisms may involve the induction of apoptosis, providing insight into therapeutic strategies targeting neoplastic diseases. -
Antiangiogenic Agent
Antiangiogenic agent 2 is a potent inhibitor of thymidine phosphorylase, exhibiting an IC50 of 39.71 μM. This compound demonstrates significant anti-angiogenic activity, making it a valuable tool for research focused on cancer biology and therapeutics targeting tumor vasculature. It can be utilized in studies aimed at understanding angiogenesis and developing novel anti-cancer strategies. -
Thymidine Analog
2’,3’,5’-Tri-O-acetyl-5,N3-dimethyluridine is a thymidine analog known for its incorporation into replicated DNA. As a nucleotide substitute, it can facilitate studies in DNA synthesis and cellular labeling. This compound is useful in research applications that require tracking of nucleic acid dynamics and the analysis of replication processes. -
Purine Nucleoside Analog
5-Aza-3'-deoxycytidine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it an important tool in cancer research. This compound is widely utilized for investigating therapeutic strategies and mechanisms underlying hematological cancers. -
Purine Nucleoside Analog
2’-O-Methyl-N1-methyladenosine is a purine nucleoside analog that targets cellular processes associated with nucleotide synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research applications. -
Purine Nucleoside Analog
1-(β-D-Xylofuranosyl)-2-thiouracil is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is useful in studies exploring the efficacy of nucleoside analogs in therapeutic strategies. -
Thymidine Analog
3’-β-C-Ethynyl-5-methyl uridine is a thymidine analog known for its insertional activity in replicated DNA. This compound serves as a valuable tool for cellular labeling and monitoring of DNA synthesis. Additionally, it contains an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it a versatile reagent in click chemistry applications. -
Purine Nucleoside Analog
Arabinosylisocytosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly effective against indolent lymphoid malignancies. Its primary mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies focusing on the cellular responses to nucleoside analogs and their therapeutic potential in treating various malignancies. -
Purine Nucleoside Analog
2-Methylamino-N6-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer therapeutics. This compound is essential for studying the biological effects of purine analogs in oncology applications. -
Nucleoside Analog
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate (2'-F-dGTP) is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. It exhibits unique properties that enable its incorporation into RNA and DNA, altering their stability and functionality. This compound is particularly valuable in studies involving molecular biology, genetic engineering, and the development of antiviral therapies. -
Purine Nucleoside Analog
5-Iodo-2'-β-C-methyl cytidine is a purine nucleoside analogue that exerts its biological effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and disrupting cellular proliferation. It serves as a valuable tool for research applications focused on cancer biology and therapeutic strategies. -
Purine Nucleoside Analog
1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analog that primarily acts on DNA synthesis pathways. Characterized by its broad antitumor activity, this compound is particularly effective against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research. -
Thymidine Analog
5’-(4,4’-Dimethoxytrityl)-5-methyluridine is a thymidine analog that exhibits insertional activity within replicated DNA. This compound is instrumental in labeling cells, facilitating the tracking of DNA synthesis, and studying nucleic acid processes. Its unique properties make it a valuable tool for molecular biology research and applications involving DNA manipulation. -
Purine Nucleoside Analog
6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analog with significant antitumor activity. It effectively targets indolent lymphoid malignancies through mechanisms that include the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable in cancer research, particularly in studying therapies aimed at lymphoid malignancies. -
Oligonucleotide
m7GpppUmpG is an oligonucleotide and an M7GpppNpG trinucleotide cap analogue. It serves as a valuable chemical tool for the synthesis of RNA containing either cap 0 or cap 1 structures. This compound is instrumental in studies involving RNA capping mechanisms and can be utilized in various RNA-based research applications, including gene expression and RNA stability investigations. -
Purine Nucleoside Analog
N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological activity is primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding cancer mechanisms and developing novel therapeutic strategies. -
Purine Nucleoside Analog
5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis. Its antitumor properties are particularly effective against indolent lymphoid malignancies, inducing apoptosis and disrupting cellular proliferation. This compound is valuable for research applications focused on cancer biology and therapeutics development. -
Purine Nucleoside Analog
5-Pyrrolidinomethyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer therapeutics. This compound is useful in exploring the biological pathways associated with nucleoside metabolism and the development of novel cancer treatment strategies. -
Purine Nucleoside Analog
1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focusing on the therapeutic effects of purine analogs in oncology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-5-fluorouridine is a purine nucleoside analogue known for its potent antitumor activity, specifically targeting indolent lymphoid malignancies. Its biological activity is primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. In addition to its therapeutic potential, 3'-Azido-3'-deoxy-5-fluorouridine serves as a versatile click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the functionalization of biological molecules. -
Nucleoside Metabolite
5-Hydroxymethyldeoxycytidylic acid is a nucleoside metabolite that plays a pivotal role in epigenetic regulation through its involvement in DNA methylation processes. It serves as an important biomarker for assessing cellular responses to environmental and developmental stimuli. This compound is utilized in various research applications, including studies on gene expression, cellular differentiation, and the mechanisms underlying cancer development. -
DAP-AT Substrate
(S)-2-Acetamido-6-oxopimelic acid serves as a substrate for N-succinyl-LL-diaminopimelate aminotransferase (DAP-AT). This compound is crucial for studying the enzymatic pathways involved in bacterial lysine biosynthesis. Its use can facilitate research into antibiotic resistance and the development of new antimicrobial agents targeting DAP-AT-related processes. -
Purine Nucleoside Analog
3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on understanding cancer biology and developing novel therapeutic strategies. -
Purine Nucleoside Analog
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its effects primarily through the inhibition of DNA synthesis and the induction of apoptotic pathways. It serves as a valuable tool in cancer research, aiding in the study of therapeutic strategies targeting purine metabolic pathways. -
Purine Nucleoside Analog
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog that inhibits DNA synthesis and promotes apoptosis, demonstrating significant antitumor activity. This reagent is primarily employed in the synthesis of modified oligonucleotides for research in cancer biology and therapeutic development targeting indolent lymphoid malignancies. Its ability to serve as an effective building block facilitates advanced studies in molecular genetics and nucleic acid research. -
Nucleoside Metabolite
4-Hydroxy-2-oxopentanoic acid is a nucleoside metabolite that plays a crucial role in cellular metabolism. It serves as an intermediate in various biochemical pathways, influencing nucleoside synthesis and metabolism. This compound can be utilized in research exploring metabolic regulation, nucleic acid synthesis, and the physiological effects of nucleoside derivatives. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it a versatile tool for various chemical biology applications. -
Plant Growth Promoter
3-Indoleglycolaldehyde is a bacterial metabolite that functions as a plant growth promoter. This compound has been shown to enhance plant growth and development, making it valuable for agricultural and horticultural research. Its unique properties may aid in studying plant biology and exploring sustainable agricultural practices. -
Oligonucleotide
m7GpppCpG is an oligonucleotide and a cap analogue of the M7GpppNpG trinucleotide. This compound serves as a valuable chemical tool for the production of RNA with cap 0 or cap 1 structures, facilitating studies in RNA biochemistry and gene expression regulation. Its application is critical in the development of mRNA therapeutics and advanced RNA-based research methodologies. -
Nucleoside Metabolite
Avicholic acid is a nucleoside metabolite that plays a significant role in cellular metabolism. It has been implicated in various biochemical pathways, making it a valuable tool for research in nucleoside signaling and metabolism. Avicholic acid is used in studies exploring its effects on cellular processes and potential therapeutic applications in related metabolic disorders. -
Uridine Analog
3-(2-Pyridinylmethyl)uridine is a uridine analog that serves as a valuable tool for biochemical research. This compound exhibits potential antiepileptic effects, making it useful for studying anticonvulsant and anxiolytic activities. Additionally, it offers opportunities for the development of novel antihypertensive agents, contributing to a better understanding of various neurological and cardiovascular functions. -
Nucleoside Analog
N4-Methyl-CTP is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound can be incorporated into RNA and DNA strands, facilitating studies in molecular biology, gene editing, and therapeutic development. Its unique methyl group may also influence nucleotide interactions, making it valuable for exploring nucleic acid structure and function. -
Nucleoside Analog
dITP (2'-Deoxyinosine-5'-triphosphate) is a nucleoside analog that serves as a building block for nucleic acid synthesis. Its key biological activity involves incorporation into DNA by DNA polymerases, enabling studies of DNA replication and repair mechanisms. dITP is widely used in molecular biology applications, including site-directed mutagenesis, nucleotide labeling, and the generation of modified nucleic acids for various research purposes. -
Nucleoside Analog
CTPαS (Rp isomer) is a nucleoside analog that serves as a critical monomer in nucleic acid synthesis. This compound is utilized in biochemical research for the development of RNA and DNA-based constructs, facilitating studies on genetic expression and molecular interactions. Its unique structure allows for incorporation into oligonucleotides, enabling advanced applications in genomics and therapeutics. -
Nucleoside Analog
EX-A8186 is a nucleoside analog designed for the synthesis of nucleic acids. This monomeric compound serves as a building block in various biochemistry applications, including the development of oligonucleotides and DNA/RNA sequencing. Its utility in the production of nucleic acid constructs makes it valuable for research in molecular biology, genetic engineering, and therapeutic development. -
Nucleoside Analog
3′-Azido-ddATP is a potent nucleoside analog that serves as a key monomer for nucleic acid synthesis. This compound, featuring an azido group at the 3′ position, is instrumental in research applications focused on developing modified nucleotides for various biochemical studies, including DNA sequencing and molecular biology techniques. Its unique structure allows for incorporation into nucleic acids, facilitating the exploration of nucleic acid interactions and functions. -
Malic acid Derivative
(2R,3S)-3-Methylmalic acid is a malic acid derivative that serves as a valuable synthon for the synthesis of 2-methyl-3-hydroxy-butyrolactones. This compound demonstrates significant utility in organic synthesis and is applicable in the development of various pharmaceuticals and bioactive molecules. Its structural characteristics make it a key intermediate in research focused on the synthesis of complex organic compounds. -
Nucleoside Analog
3'-O-TBDMS-2'-O-Me-rG(iBu) is a nucleoside analog that serves as a valuable monomeric precursor for nucleic acid synthesis. This compound enhances the stability and solubility of oligonucleotides, making it ideal for a variety of molecular biology applications. It is particularly useful in the synthesis of modified RNA molecules and can facilitate studies in gene expression, RNA interference, and other RNA-based technologies. -
Nucleoside Analog
DMTr-2'-dG(iBu)-3'-S-CE-phosphoramidite is a nucleoside analog designed for incorporation into oligonucleotides during nucleic acid synthesis. This reagent features a DMTr protecting group and can facilitate the addition of sulfur at the 3' position, enhancing the stability and functionality of synthesized nucleic acids. It is ideal for applications in therapeutic and diagnostic research involving nucleic acid-based technologies. -
Nucleoside Analog
2'-Deoxy-3',5'-GDP (pdGp) is a nucleoside analog that serves as a crucial monomer for nucleic acid synthesis. Its structure allows for incorporation into RNA and DNA, facilitating studies on nucleic acid behavior and functions. This reagent is essential for various biochemical applications, including the development of oligonucleotides and the exploration of enzymatic mechanisms involving nucleotides. -
Nucleoside Analog
DMTr-2'-F-dU-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for applications in nucleic acid synthesis. This phosphoramidite serves as a key building block for the preparation of modified oligonucleotides, enabling the introduction of fluorinated bases into nucleic acids. Its unique properties facilitate diverse research applications, including the study of gene expression and the development of RNA therapeutics. -
Nucleoside Analog
5-OH-CTP (5-hydroxy cytidine triphosphate) is a nucleoside analog that serves as a vital building block in nucleic acid synthesis. Its unique structure allows it to incorporate into RNA, facilitating various biochemical and biophysical studies. This reagent is applicable in research focused on RNA synthesis, enzymatic reactions, and the investigation of nucleic acid interactions. -
Purine Nucleoside Analog
3’-O-Methyl inosine is a purine nucleoside analog known for its potent antitumor activity. This compound primarily targets indolent lymphoid malignancies through mechanisms that include inhibition of DNA synthesis and induction of apoptosis. It serves as a valuable tool in cancer research, advancing the understanding of therapeutic approaches against various tumors. -
Nucleoside Analog
DMTr-dA(dmf)-3'-CE-phosphoramidite is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. It facilitates the construction of oligonucleotides through phosphoramidite chemistry, enabling the incorporation of modified nucleotides. This reagent is essential for researchers studying gene expression, RNA interference, and the development of antisense oligonucleotides. -
Nucleoside Analog
dGDP sodium (2'-Deoxyguanosine-5'-diphosphate sodium) serves as a nucleoside analog, functioning as a vital building block for nucleic acid synthesis. Its incorporation into oligonucleotides allows for the exploration of molecular biology applications, including genetic engineering and the study of nucleotide metabolism. This reagent is essential for researchers working on synthetic biology and therapeutic development. -
Nucleoside Analog
5'-O-DMTr-3'-O-Me-rA(Bz) is a nucleoside analog characterized by its protective groups that facilitate nucleic acid synthesis. This compound serves as a key monomer for the construction of oligonucleotides, enabling precise modifications during the synthesis process. Its structural components support improved stability and compatibility in various biochemical applications, making it valuable for nucleic acid research and development. -
Nucleoside Analog
LNA-AMP is a nucleoside analog that serves as a building block for the synthesis of oligonucleotides. This compound enhances the stability and affinity of nucleic acid interactions, making it valuable for applications in molecular biology, gene expression studies, and antisense research. Its unique properties facilitate the design of more effective RNA-targeting therapeutics and diagnostics.
