Fig. 1 · Structure

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3’-Azido-3’-deoxy-5-fluorouridine

Purine Nucleoside Analog

3'-Azido-3'-deoxy-5-fluorouridine is a purine nucleoside analogue known for its potent antitumor activity, specifically targeting indolent lymphoid malignancies. Its biological activity is primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. In addition to its therapeutic potential, 3'-Azido-3'-deoxy-5-fluorouridine serves as a versatile click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the functionalization of biological molecules.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 307520-05-4
Applications Purine Nucleoside Analog
Formula C9H10FN5O5
Molecular Weight 287.20
SMILES
OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N(C=C2F)C(NC2=O)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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