Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding cancer cell metabolism and therapeutics. -
Nucleoside Metabolite
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is a nucleoside metabolite that plays a critical role in cellular metabolism. It is involved in the synthesis and regulation of nucleotide pools, making it useful for studying metabolic pathways and nucleoside biosynthesis in various biological systems. This compound is valuable for research applications related to enzymatic activity and cellular signaling. -
Purine Nucleoside Analog
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mode of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound is ideal for investigations into the mechanisms of tumorigenesis and the development of novel anticancer strategies. -
Uridine Analog
4’-C-Methyl-5-methoxyuridine is an analog of uridine, known for its potential antiepileptic properties. This compound can be utilized in research to investigate anticonvulsant and anxiolytic activities, as well as in the development of novel antihypertensive agents. Its structural modifications allow for the exploration of biological mechanisms related to uridine's effects in neurological and cardiovascular systems. -
Sterol Metabolite
7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite that functions primarily as a modulator of various biological processes. This compound is formed through the 7α-hydroxylation and subsequent oxidation of 25-hydroxycholesterol, influencing cholesterol metabolism and immune response pathways. It is instrumental in research focused on lipid biology, neuroinflammation, and sterol-related signaling mechanisms. -
Nucleotide
Adenosine tetraphosphate is a natural nucleotide that plays a critical role in various biological processes. It has been shown to reduce intraocular pressure in normotensive rabbit eyes, making it a valuable compound for research into ocular health and related therapeutic applications. This reagent can be utilized in studies focusing on nucleotide signaling and its physiological effects. -
Purine Nucleoside Analog
5′-Azido-2′,5′-dideoxy-2′-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or reactive DBCO/BCN groups, respectively. These characteristics make it a valuable tool for various research applications in chemical biology and drug development. -
Hypoxanthine Analog
2-Chloro-6-methoxypurine riboside is a hypoxanthine analog known for its mechanism as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. This compound exhibits cytoprotective properties by inhibiting PARP activity, thereby preventing peroxynitrite-induced mitochondrial depolarization and the subsequent production of superoxides. Its anti-inflammatory effects and role as an indicator of hypoxia make it valuable for research applications in cellular metabolism and oxidative stress studies. -
Nucleoside Metabolite
Demethylphosphinothricin is a nucleoside metabolite that functions as a potent inhibitor of glutamine synthetase. Its primary mechanism involves the inhibition of amino acid metabolism, leading to disruption of nitrogen assimilation in plants and some microorganisms. This compound is valuable in agricultural research for studying herbicide resistance and in biochemistry for exploring metabolic pathways related to amino acid biosynthesis. -
Adenosine Analog
2′-β-C-Methyl-2-methoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. Its applications extend to research involving cardiovascular function and cancer biology, making it a valuable tool for exploring therapeutic strategies in these areas. -
Purine Nucleoside Analog
3’-β-Amino-2’,3’-dideoxy-5’-O-trityl-5-methyl uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, contributing to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. Its antineoplastic mechanisms involve inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the therapeutic potential of purine analogs in oncology. -
Adenosine Analog
N6-(4-Methoxybenzyl)adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure enables investigations into adenosine signaling pathways and their implications in various biological processes. -
Adenosine Analog
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. This compound is valuable in research focused on vascular biology and cancer therapeutics, offering insights into adenosine receptor signaling pathways and their clinical implications. -
Purine Nucleoside Analog
2’-C-β-Methyl-4-deoxyuridine is a purine nucleoside analogue that inhibits DNA synthesis and induces apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. It is valuable in cancer research applications aimed at understanding the mechanisms of action of nucleoside analogues in tumor cell proliferation and survival. -
Purine Nucleoside Analog
2’-β-C-Methyl-5-fluorouridine is a purine nucleoside analog known for its antitumor properties. This compound exhibits significant biological activity by inhibiting DNA synthesis and inducing apoptosis, making it particularly valuable for the study of indolent lymphoid malignancies. Its applications extend to cancer research, where it can be utilized to explore therapeutic strategies and mechanisms underlying tumor progression. -
Purine Nucleoside Analog
2-Amino-2′-C-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, providing insights into therapeutic strategies for lymphoid malignancies. -
Pyrimidine Nucleoside Analog
Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a pyrimidine nucleoside analog that targets nucleic acid synthesis pathways. This compound exhibits significant activities, including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. It is a valuable tool in the study of biochemical processes and the development of therapeutic agents in cancer and viral research. -
Thymidine Analog
5’(R)-C-Methyl-5-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is valuable for labeling cells and monitoring DNA synthesis in various biological assays. Its unique structure allows for the exploration of nucleoside metabolism and the study of DNA-related processes in cellular systems. -
Purine Nucleoside Analog
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that targets nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research and therapeutic studies. -
Purine Nucleoside Analog
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development for hematological malignancies. -
Cytidine Analog
N4-Methylarabinocytidine is a cytidine nucleoside analog that inhibits DNA methyltransferases, thereby affecting DNA methylation processes. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable for cancer research and studies on epigenetic regulation. Its role as a nucleoside analog provides a tool for exploring the mechanisms of DNA modification and gene expression control in various biological contexts. -
Purine Nucleoside Analog
5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine is a purine nucleoside analog designed to interfere with DNA synthesis and induce apoptosis in malignant cells. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable tool in cancer research. Its unique structural modifications enhance its efficacy as a pharmacological agent in studying cancer-related pathways and therapeutic interventions. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine functions as a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound's mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development. -
Cytidine Analog
1-(β-D-Xylofuranosyl)-5-methylcytosine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool in epigenetics research. It is suitable for studies investigating the role of DNA methylation in gene regulation and cancer biology. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant anticancer activity primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound is particularly effective against indolent lymphoid malignancies, making it a valuable tool in cancer research. Additionally, it serves as a click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. -
Purine Nucleoside Analog
5'-O-Triphenylmethyl-2'-deoxyuridine is a purine nucleoside analog recognized for its ability to inhibit DNA synthesis and induce apoptosis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. It serves as a valuable tool for researchers exploring therapeutic strategies in cancer treatment and mechanisms of nucleoside analogs in oncology. -
Guanosine Analog
TLR7 Agonist 13 is a guanosine analog that activates Toll-like receptor 7 (TLR7), leading to immunostimulatory effects and the induction of type I interferons, which may confer antiviral properties. This compound is utilized in various research applications to study innate immune responses. Additionally, TLR7 Agonist 13 features an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for click chemistry, facilitating its incorporation into diverse bioconjugation strategies. -
Nucleoside Metabolite
2'-Deoxy-5-hydroxymethyl-CTP is a nucleoside metabolite that serves as a key substrate in nucleic acid synthesis and metabolism. Its unique hydroxymethyl modification imparts distinctive biochemical properties that can influence enzymatic activity. This compound is valuable for research into nucleoside analogs, metabolic pathways, and the synthesis of modified nucleotides for therapeutic applications. -
Nucleoside Compound
5-(N-Methyl-N-trifluoroacetyl)aminomethyl uridine is a nucleoside compound that serves as a versatile intermediate in nucleic acid chemistry. Its structural modifications provide insights into the mechanisms of nucleoside incorporation and metabolism. This compound is applicable in research areas involving RNA synthesis, enzymatic studies, and the development of nucleotide analogs for therapeutic applications. -
Purine Nucleoside Analog
N4-Benzoyl-2'-O-(2-methoxyethyl)cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Research applications include studying its effects on cellular proliferation and evaluating its potential in cancer therapy. -
Purine Nucleoside Analog
8-Hydroxy-xyloguanosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at elucidating the roles of purine metabolism in cancer biology and exploring potential therapeutic applications. -
Purine Nucleoside Analog
2’-β-C-Ethynyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Additionally, this compound features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. -
Purine Nucleoside Analog
Uridine-5-oxyacetic acid is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studies aimed at understanding the therapeutic potential of purine analogs in oncological applications. -
Nucleoside Metabolite
5-Hydroxyindolepyruvate is a nucleoside metabolite that plays a critical role in the metabolism of tryptophan. It has been shown to influence various biological pathways, including neurochemical signaling and cellular growth. This compound is used in research applications involving neurotransmitter synthesis and metabolic studies, providing insights into the physiological roles of indole derivatives. -
Purine Nucleoside Analog
4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its biological activity is primarily attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for researchers investigating cancer treatment and the underlying biology of nucleoside analogs in therapeutic applications. -
Purine Nucleoside Analog
5-Methoxy-4-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for research in cancer biology. This reagent is useful for studies exploring the effects of nucleoside analogs on cellular proliferation and programmed cell death. -
Purine Nucleoside Analog
N6-Isopentenyl-2’-deoxy adenosine, also known as 2’-deoxy riboprine, is a purine nucleoside analog that primarily targets DNA synthesis inhibition. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are attributed to mechanisms such as the induction of apoptosis and disruption of cell proliferation, making it a valuable reagent for cancer research applications. -
Purine Nucleoside Analog
5-Methyl-4-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer therapeutics and cell proliferation studies. This compound is useful for investigating the effects of purine metabolism and nucleoside analogs in various biological contexts. -
Thymidine Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-methyl uridine is a thymidine analog that effectively incorporates into replicated DNA. This compound exhibits insertional activity, facilitating the labeling of cells for tracking DNA synthesis. Its unique structural modifications enable specific applications in molecular biology and genetic research, making it a valuable tool for studying DNA replication dynamics. -
Purine Nucleoside Analog
3′-Deoxy-3′-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies aimed at understanding the molecular underpinnings of cancer and evaluating potential therapeutic strategies. -
Purine Nucleoside Analog
5'-Deoxy-5-methyluridine is a purine nucleoside analog known for its significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable in research aimed at elucidating mechanisms of cancer progression and developing novel therapeutic strategies. -
Thymidine Analog
5-Naphthyl-β-methylaminocarbony-3'-O-acetyl-2'-O-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is effective for cellular labeling and monitoring DNA synthesis, making it valuable in molecular biology and genetics research. Its unique structure allows for optimized incorporation into nucleic acids, facilitating various applications in DNA manipulation and analysis. -
Guanine Nucleotide
Guanosine 5'-triphosphate 3'-diphosphate is a guanine nucleotide that serves as a crucial intermediate in RNA synthesis and protein synthesis mechanisms. By providing essential energy and phosphate groups, it facilitates cellular processes such as signal transduction and metabolic regulation. This compound is valuable for research applications focused on nucleic acid biochemistry and enzyme kinetics. -
Precursor of Trapping Product
15-Hydroxy-5,6-oxido-7,9,11,13-eicosatetraenoic acid is an important precursor in the biosynthesis of lipoxins in human leukocytes. This compound is integral in the formation of trapping products, which play critical roles in inflammatory processes and resolution mechanisms. It is utilized in research to elucidate the pathways involved in eicosanoid metabolism and the physiological implications of lipoxin signaling. -
Adenosine Analog
2'-Chloro-N6-benzyl adenosine is a chemically modified adenosine analog. This compound primarily functions as a smooth muscle vasodilator and exhibits potential inhibitory effects on cancer progression. Its unique structural properties make it a valuable tool for research in vascular biology and oncology, facilitating studies on adenosine signaling pathways and their implications in various physiological and pathological conditions. -
Purine Nucleoside Analog
7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in susceptible cancer cells. This compound serves as a valuable tool in cancer research, facilitating the exploration of therapeutic strategies targeting purine metabolism and cell proliferation. -
Nucleoside Metabolite
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine is a nucleoside metabolite that plays a vital role in bacterial cell wall biosynthesis. It serves as a precursor in the synthesis of peptidoglycan, making it essential for the integrity and maintenance of bacterial cell structure. This compound is particularly useful in research applications focused on understanding bacterial physiology, antibiotic development, and the mechanisms of resistance. -
Guanosine Analog
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory properties, leading to the induction of type I interferons in various animal models, thereby demonstrating significant antiviral effects. It serves as a valuable tool in research studies focusing on immune response modulation and antiviral therapies. -
Purine Nucleoside Analog
3’-O-MOE-5MeU-2’-phosphoramidite is a purine nucleoside analog that serves as a key reagent in nucleic acid synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms including the inhibition of DNA synthesis and the induction of apoptosis. Its utility in research includes applications in the development of therapeutic agents and the study of nucleic acid interactions.
