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4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine

Purine Nucleoside Analog

4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its biological activity is primarily attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for researchers investigating cancer treatment and the underlying biology of nucleoside analogs in therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1848223-48-2
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₂N₂O₅
Molecular Weight	240.21
SMILES	C=C1[C@@H](O)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.