Droxinostat

Catalog No.: A10337
HDAC inhibitor
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 that shows comparable inhibition of HDAC6 and HDAC8 with IC50 = 2.47 and 1.46 μmol/L, respectively.
Grouped product items
Product Name Price Stock Qty
Droxinostat 5mg
Special Price $32.00 Regular Price $40.00
In stock
Droxinostat 10mg
Special Price $56.00 Regular Price $70.00
In stock
Droxinostat 50mg
Special Price $256.00 Regular Price $320.00
In stock
Droxinostat 100mg
Special Price $464.00 Regular Price $580.00
In stock
Droxinostat 10mM * 1mL in DMSO
Special Price $62.40 Regular Price $78.00
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Adooq Products cited in reputable paper
Biological Activity
Discription Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 that shows comparable inhibition of HDAC6 and HDAC8 with IC50 = 2.47 and 1.46 μmol/L, respectively.
Targets
Target Value
Product Information
Catalog Num A10337
Formula C11H14ClNO3
Molecular Weight 243.7
CAS Number 99873-43-5
SMILES CC1=C(C=CC(=C1)Cl)OCCCC(=O)NO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 47 mg/mL (192.86 mM)
Water Insoluble
Ethanol 47 mg/mL (192.86 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.03 mL 205.17 mL 410.34 mL
0.5 mM 8.21 mL 41.03 mL 82.07 mL
1 mM 4.1 mL 20.52 mL 41.03 mL
5 mM 0.82 mL 4.1 mL 8.21 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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