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|Storage||at -20°C 3 years Powder|
|Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 that shows comparable inhibition of HDAC6 and HDAC8 with IC50 = 2.47 and 1.46 μmol/L, respectively.|
|Solubility (25°C) *||In vitro||DMSO||49 mg/mL (201.07 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||49 mg/mL (201.07 mM)|
|In vivo||30% propylene glycol, 5% Tween 80, 65% D5W||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||41.03 mL||205.17 mL||410.34mL|
|0.5 mM||8.21 mL||41.03 mL||82.07 mL|
|1 mM||4.1 mL||20.52 mL||41.03 mL|
|5 mM||0.82 mL||4.1 mL||8.21 mL|
*The above data is based on the productmolecular weight 243.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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