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- Paudel DB, .et al. Expression and antiviral function of ARGONAUTE 2 in Nicotiana benthamiana plants infected with two isolates of tomato ringspot virus with varying degrees of virulence, Virology, 2018, Nov;524:127-139 PMID: 30195250
|Storage||at -20°C 3 years Powder|
|SMILES||CCOC(=O)[[email protected]@H]1[[email protected]](O1)C(=O)N[[email protected]@H](CC(C)C)C(=O)NCCC(C)C|
|Chemical Name||ethyl (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylate|
|E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.|
|Solubility (25°C)*||In vitro||DMSO||68 mg/mL (198.58 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||68 mg/mL (198.58 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||29.2 mL||146.02 mL||292.03mL|
|0.5 mM||5.84 mL||29.2 mL||58.41 mL|
|1 mM||2.92 mL||14.6 mL||29.2 mL|
|5 mM||0.58 mL||2.92 mL||5.84 mL|
*The above data is based on the productmolecular weight 342.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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