E 64d (Aloxistatin)

Catalog No.: A13259

Cysteine Protease inhibitor

E 64d (Aloxistatin)

E 64d (Aloxistatin) Chemical Structure

CAS NO. 88321-09-9

E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.

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5 mg

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Special Price $40.00

10 mg

Regular Price: $80.00

Special Price $64.00

25 mg

Regular Price: $140.00

Special Price $112.00

10mM * 1mL in DMSO

Regular Price: $55.00

Special Price $44.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Paudel DB, .et al. Expression and antiviral function of ARGONAUTE 2 in Nicotiana benthamiana plants infected with two isolates of tomato ringspot virus with varying degrees of virulence, Virology, 2018, Nov;524:127-139 PMID: 30195250

Biological Activity

E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
Targets
Cysteine protease
In vitro (25°C) DMSO 67 mg/mL (195.66 mM)
Water Insoluble
Ethanol 67 mg/mL
In vivo 2% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.2 mL 146.02 mL 292.03 mL
0.5 mM 5.84 mL 29.2 mL 58.41 mL
1 mM 2.92 mL 14.6 mL 29.2 mL
5 mM 0.58 mL 2.92 mL 5.84 mL

*The above data is based on the productmolecular weight 342.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13259
Actions Inhibitor
CAS No. 88321-09-9
Formula C17H30N2O5
M. Wt 342.43
Purity >98%
Synonyms E-64d, E64d
SMILES CCOC(=O)[[email protected]@H]1[[email protected]](O1)C(=O)N[[email protected]@H](CC(C)C)C(=O)NCCC(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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