Enopeptin A is a depsipeptide antibiotic primarily targeting Gram-positive and certain Gram-negative bacteria. Isolated from Streptomyces sp. RK-1051, it demonstrates potent activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, it exhibits efficacy against mutant strains of Escherichia coli and Pseudomonas aeruginosa, with MICs of 200 μg/mL. Enopeptin A is not effective against fungal pathogens, making it a valuable compound for studies focused on antibiotic resistance and bacterial infections.
Enopeptin A is a depsipeptide antibiotic primarily targeting Gram-positive and certain Gram-negative bacteria. Isolated from Streptomyces sp. RK-1051, it demonstrates potent activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, it exhibits efficacy against mutant strains of Escherichia coli and Pseudomonas aeruginosa, with MICs of 200 μg/mL. Enopeptin A is not effective against fungal pathogens, making it a valuable compound for studies focused on antibiotic resistance and bacterial infections.
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