Fig. 1 · Structure
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Flurocitabine
Antieoplastic Agent
Flurocitabine, a fluorinated analog of cytosine arabinoside, acts as an antineoplastic agent by undergoing partial hydrolysis in vivo to produce two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). This compound demonstrates significant antitumor activity and has shown promise in phase I clinical studies for acute leukemia and various solid tumors. Its unique mechanism of action makes Flurocitabine a valuable tool for cancer research and therapy development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 37717-21-8 |
| Applications | Antieoplastic Agent |
| Formula | C9H10FN3O4 |
| Molecular Weight | 243.19 |
| Synonyms | 5-Fluorocyclocytidine; 5'-Fluorocyclocytidine |
| SMILES | O[C@H]1[C@@]2([H])[C@](O[C@@H]1CO)([H])N3C(O2)=NC(C(F)=C3)=N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.