Fmoc-12-aminododecanoic acid is a PROTAC linker characterized by an alkane chain with a terminal Fmoc-protected amine and a carboxylic acid group. This compound serves as a building block in the synthesis of PROTACs, facilitating targeted protein degradation studies. The Fmoc group can be readily deprotected in basic conditions, releasing a free amine for subsequent conjugations, while the terminal carboxylic acid allows for stable amide bond formation with primary amines using suitable coupling reagents.
Fmoc-12-aminododecanoic acid is a PROTAC linker characterized by an alkane chain with a terminal Fmoc-protected amine and a carboxylic acid group. This compound serves as a building block in the synthesis of PROTACs, facilitating targeted protein degradation studies. The Fmoc group can be readily deprotected in basic conditions, releasing a free amine for subsequent conjugations, while the terminal carboxylic acid allows for stable amide bond formation with primary amines using suitable coupling reagents.
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