G4/HDAC-IN-1 is a dual-targeting compound that inhibits histone deacetylase (HDAC) activity and promotes the formation of G-quadruplex (G4) structures. With an IC50 value of 1.1 μM, this reagent effectively impedes the proliferation of triple-negative breast cancer (TNBC) cells and suppresses tumor growth in TNBC xenograft models. G4/HDAC-IN-1 is highly relevant for research into cancer biology and potential therapeutic strategies.
G4/HDAC-IN-1 is a dual-targeting compound that inhibits histone deacetylase (HDAC) activity and promotes the formation of G-quadruplex (G4) structures. With an IC50 value of 1.1 μM, this reagent effectively impedes the proliferation of triple-negative breast cancer (TNBC) cells and suppresses tumor growth in TNBC xenograft models. G4/HDAC-IN-1 is highly relevant for research into cancer biology and potential therapeutic strategies.
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