GANT61

Catalog No.: A13252
GLI antagonist
GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
Grouped product items
Product Name Price Stock Qty
GANT61 10mg
$75.00
In stock
GANT61 25mg
$150.00
In stock
GANT61 50mg
$280.00
In stock
GANT61 100mg
$480.00
In stock
GANT61 10mM * 1mL in DMSO
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GANT61 has been cited by 2 publications
  • Cheng Zhou, .et al. , Cell Death Dis, 2021, Mar 3;12(3):231 PMID: 33658491
  • Hui Liang, .et al. , Sci Rep, 2017, 7: 40361 PMID: 28098170
  • Biological Activity
    Discription GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
    Targets
    Target Value
    Product Information
    Catalog Num A13252
    Formula C27H35N5
    Molecular Weight 429.61
    CAS Number 500579-04-4
    SMILES CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
    Synonyms NSC136476, NSC-136476, GANT 61, GANT-61
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Insoluble
    Water Insoluble
    Ethanol 11 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.28 mL 116.38 mL 232.77 mL
    0.5 mM 4.66 mL 23.28 mL 46.55 mL
    1 mM 2.33 mL 11.64 mL 23.28 mL
    5 mM 0.47 mL 2.33 mL 4.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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