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GANT61

Catalog No.: A13252
GLI antagonist
Adooq's GANT61 has been cited by 3 publications
GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
GANT61
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$45.00
In stock
10mg
$70.00
In stock
25mg
$145.00
In stock
50mg
$275.00
In stock
100mg
$445.00
In stock
500mg
$1,045.00
In stock
10mM * 1mL in DMSO
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GANT61 has been cited by 3 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Cheng Zhou, .et al. , Cell Death Dis, 2021, Mar 3;12(3):231 PMID: 33658491
  • Hui Liang, .et al. , Sci Rep, 2017, 7: 40361 PMID: 28098170
    • Biological Activity
    Discription GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A13252
    Formula C27H35N5
    Molecular Weight 429.61
    CAS Number 500579-04-4
    SMILES CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
    Synonyms NSC136476, NSC-136476, GANT 61, GANT-61
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO Insoluble
    Water Insoluble
    Ethanol 11 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.28 mL 116.38 mL 232.77 mL
    0.5 mM 4.66 mL 23.28 mL 46.55 mL
    1 mM 2.33 mL 11.64 mL 23.28 mL
    5 mM 0.47 mL 2.33 mL 4.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Stem Cells/Wnt > Hedgehog
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