GDC-0941 (Pictilisib)

GDC-0941 is a potent, selective, orally bioavailable inhibitor of class I PI3 kinase (PI3K) , with IC50 values (nM) of 3, 33, 3, 75, 1230 and 580 for p110 α, β, δ and γ isoforms, DNA-PK and mTOR respectively.
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Product Name Price Stock Qty
GDC-0941 5mg
$40.00
In stock
GDC-0941 10mg
$50.00
In stock
GDC-0941 50mg
$75.00
In stock
GDC-0941 200mg
$210.00
In stock
GDC-0941 10mM * 1mL in DMSO
$50.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GDC-0941 (Pictilisib) has been cited by 3 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Li T, .et al. , Oncogene, 2018, Nov;37(47):6180-6194 PMID: 30013190
  • Joo Sang Lee, .et al. , Nat Commun, 2018, 9: 2546 PMID: 29959327
  • Biological Activity
    Discription GDC-0941 is a potent, selective, orally bioavailable inhibitor of class I PI3 kinase (PI3K) , with IC50 values (nM) of 3, 33, 3, 75, 1230 and 580 for p110 α, β, δ and γ isoforms, DNA-PK and mTOR respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A10421
    Formula C23H27N7O3S2
    Molecular Weight 513.6
    CAS Number 957054-30-7
    SMILES CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 40 mg/mL (77.87 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.47 mL 97.35 mL 194.7 mL
    0.5 mM 3.89 mL 19.47 mL 38.94 mL
    1 mM 1.95 mL 9.74 mL 19.47 mL
    5 mM 0.39 mL 1.95 mL 3.89 mL
    Useful Calculator

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