Griseolic acid C, an antibiotic compound, is identified as a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase (EC 3.1.4.17) with an IC50 of 0.12 μM, as demonstrated in studies utilizing rat brain extracts. Isolated from Streptomyces griseoaurantiacus SANK43894, Griseolic acid C exhibits significant biological activity that may be beneficial in various research applications related to cellular signaling and microbial resistance.
Griseolic acid C, an antibiotic compound, is identified as a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase (EC 3.1.4.17) with an IC50 of 0.12 μM, as demonstrated in studies utilizing rat brain extracts. Isolated from Streptomyces griseoaurantiacus SANK43894, Griseolic acid C exhibits significant biological activity that may be beneficial in various research applications related to cellular signaling and microbial resistance.
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