Signaling Pathway
Product type
Important Notice: For research use only. We do not sell to patients.
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| Discription | Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. | |||||
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| Targets |
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| Cell Research |
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| Catalog Num | A15809 |
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| Formula | C18H16Cl2F2N4O2 |
| Molecular Weight | 429.25 |
| CAS Number | 1047634-65-0 |
| SMILES | CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl |
| Synonyms | GSK2141795, GSK2141795, Uprosertib, GSK 795 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 80 mg/mL (186.36 mM) | |
| Water | Insoluble | ||
| Ethanol | 80 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.3 mL | 116.48 mL | 232.96 mL |
| 0.5 mM | 4.66 mL | 23.3 mL | 46.59 mL |
| 1 mM | 2.33 mL | 11.65 mL | 23.3 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
