GSK2141795 (Uprosertib, GSK795)

Catalog No.: A15809
Akt inhibitor
Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
Grouped product items
Product Name Price Stock Qty
GSK2141795 5mg
Special Price $64.80 Regular Price $81.00
In stock
GSK2141795 10mg
Special Price $110.40 Regular Price $138.00
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GSK2141795 25mg
Special Price $194.40 Regular Price $243.00
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Biological Activity
Discription Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
Targets
Target Value
Product Information
Catalog Num A15809
Formula C18H16Cl2F2N4O2
Molecular Weight 429.25
CAS Number 1047634-65-0
SMILES CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
Synonyms GSK2141795, GSK2141795, Uprosertib, GSK 795
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 80 mg/mL (186.36 mM)
Water Insoluble
Ethanol 80 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.3 mL 116.48 mL 232.96 mL
0.5 mM 4.66 mL 23.3 mL 46.59 mL
1 mM 2.33 mL 11.65 mL 23.3 mL
5 mM 0.47 mL 2.33 mL 4.66 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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