GSK2141795 (Uprosertib, GSK795)

Catalog No.: A15809

Akt inhibitor

GSK2141795 (Uprosertib, GSK795) Chemical Structure

CAS NO. 1047634-65-0

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$150.00
25 mg
$370.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
Targets
Akt3 Akt1 Akt2
38 nM180 nM328 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.3 mL 116.48 mL 232.96 mL
0.5 mM 4.66 mL 23.3 mL 46.59 mL
1 mM 2.33 mL 11.65 mL 23.3 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15809
Actions Inhibitor
M. Wt 429.25
Formula C18H16Cl2F2N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1047634-65-0
Synonyms GSK2141795, GSK2141795, Uprosertib, GSK 795
SMILES CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy GSK2141795 (Uprosertib, GSK795) | GSK2141795 (Uprosertib, GSK795) Supplier | purchase GSK2141795 (Uprosertib, GSK795) | GSK2141795 (Uprosertib, GSK795) cost | GSK2141795 (Uprosertib, GSK795) manufacturer | order GSK2141795 (Uprosertib, GSK795) | GSK2141795 (Uprosertib, GSK795) distributor | buy 1047634-65-0| 1047634-65-0 Supplier | purchase 1047634-65-0 | 1047634-65-0 cost | 1047634-65-0 manufacturer | order 1047634-65-0 | 1047634-65-0 distributor
Rewards