H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
Targets
Target
Value
Product Information
Catalog Num
A15101
Formula
C16H21N3O2S
Molecular Weight
319.42
CAS Number
451462-58-1
SMILES
CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C
Synonyms
H 1152, H1152
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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