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H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.31 mL | 156.53 mL | 313.07 mL |
| 0.5 mM | 6.26 mL | 31.31 mL | 62.61 mL |
| 1 mM | 3.13 mL | 15.65 mL | 31.31 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
*The above data is based on the productmolecular weight 319.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15101 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 451462-58-1 |
| Formula | C16H21N3O2S |
| M. Wt | 319.42 |
| Purity | >98% |
| Synonyms | H 1152, H1152 |
| SMILES | CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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