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HD-800

Catalog No.: A54936
Tubulin Inhibitor
HD-800 is a potent tubulin inhibitor, exhibiting an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. This compound is valuable for generating the radioactive tracer [11C]HD-800, which is capable of penetrating the blood-brain barrier. [11C]HD-800 serves as a useful tool for positron emission tomography (PET) applications in studying various neurological disorders.
HD-800 1204408-27-4 Tubulin Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHD-800 is a potent tubulin inhibitor, exhibiting an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. This compound is valuable for generating the radioactive tracer [11C]HD-800, which is capable of penetrating the blood-brain barrier. [11C]HD-800 serves as a useful tool for positron emission tomography (PET) applications in studying various neurological disorders.
Product Information
Catalog NumA54936
FormulaC15H15N3O2
Molecular Weight269.30
CAS Number1204408-27-4
SMILESN=1C=NC(=C2C1OC=C2C)N(C3=CC=C(OC)C=C3)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Cytoskeleton > Microtubule/Tubulin