HDAC-IN-52

Catalog No.: A26448
HDAC Inhibitor
HDAC-IN-52 is a pyridine-based inhibitor targeting histone deacetylases (HDACs) with IC50 values of 0.189 μM for HDAC1, 0.227 μM for HDAC2, 0.440 μM for HDAC3, and 0.446 μM for HDAC10. This compound exhibits potent HDAC inhibition, making it a valuable tool for investigating epigenetic regulation in cancer research. Its application extends to the study of cell differentiation, apoptosis, and potential therapeutic strategies in oncology.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$135.00
In stock
10mg
$205.00
In stock
25mg
$315.00
In stock
50mg
$420.00
In stock
100mg
$555.00
In stock
200mg
$725.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHDAC-IN-52 is a pyridine-based inhibitor targeting histone deacetylases (HDACs) with IC50 values of 0.189 μM for HDAC1, 0.227 μM for HDAC2, 0.440 μM for HDAC3, and 0.446 μM for HDAC10. This compound exhibits potent HDAC inhibition, making it a valuable tool for investigating epigenetic regulation in cancer research. Its application extends to the study of cell differentiation, apoptosis, and potential therapeutic strategies in oncology.
Product Information
Catalog NumA26448
FormulaC24H20N4O2
Molecular Weight396.44
CAS Number2075787-77-6
SMILESNC1=CC=CC=C1NC(C2=NC=C(C=C2)NC(CC3=CC4=C(C=C3)C=CC=C4)=O)=O
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