HDAC6-IN-75 is a potent inhibitor of histone deacetylase 6 (HDAC6) with an IC50 value of 0.17 nM. This compound is capable of inducing the accumulation of acetylated α-tubulin in glioma cells, leading to significant alterations in cell cycle dynamics, an increase in SubG1 cell populations, and the promotion of apoptosis in both glioma cells and glioblastoma stem cells. HDAC6-IN-75 is particularly useful for research applications focused on glioma.
HDAC6-IN-75 is a potent inhibitor of histone deacetylase 6 (HDAC6) with an IC50 value of 0.17 nM. This compound is capable of inducing the accumulation of acetylated α-tubulin in glioma cells, leading to significant alterations in cell cycle dynamics, an increase in SubG1 cell populations, and the promotion of apoptosis in both glioma cells and glioblastoma stem cells. HDAC6-IN-75 is particularly useful for research applications focused on glioma.
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