Catalog No.: A14197

HDAC6 inhibitor


HPOB Chemical Structure

CAS NO. 1429651-50-2

HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM).

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10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Biological Activity

HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM).
Target Value
HDAC6IC50: 56nM
HDAC3IC50: 1.7μM
HDAC8IC50: 2.8μM
HDAC1IC50: 2.9μM
HDAC10IC50: 3.0μM
HDAC2IC50: 4.4μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC7IC50: >10μM
HDAC9IC50: >10μM
HDAC11IC50: >10μM
In vitro DMSO 60 mg/mL (190.87 mM)
Water Insoluble
Ethanol Warmed: 37 mg/mL (117.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.82 mL 159.08 mL 318.17 mL
0.5 mM 6.36 mL 31.82 mL 63.63 mL
1 mM 3.18 mL 15.91 mL 31.82 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14197
Actions Inhibitor
CAS No. 1429651-50-2
Formula C17H18N2O4
M. Wt 314.3
Purity >98%
Synonyms 0

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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