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HDAC6 inhibitor

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Catalog No. A14197

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
HPOB 10mg A14197-10

Regular Price: $60.00

Special Price: $54.00

HPOB 25mg A14197-25

Regular Price: $120.00

Special Price: $108.00

HPOB 50mg A14197-50

Regular Price: $200.00

Special Price: $180.00

HPOB 10mM * 1mL in DMSO A14197-10mM-D

Regular Price: $55.00

Special Price: $49.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM).


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Chemical Information

Catalog Num A14197
Actions Inhibitor
M. Wt 314.3
Formula C17H18N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1429651-50-2
Synonyms 0

Biological Activity

HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM).
Target Value
HDAC6IC50: 56nM
HDAC3IC50: 1.7μM
HDAC8IC50: 2.8μM
HDAC1IC50: 2.9μM
HDAC10IC50: 3.0μM
HDAC2IC50: 4.4μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC7IC50: >10μM
HDAC9IC50: >10μM
HDAC11IC50: >10μM


Solubility (25°C)* In vitro DMSO 62 mg/mL (197.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol 38 mg/mL heating (120.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.82 mL 159.08 mL 318.17mL
0.5 mM 6.36 mL 31.82 mL 63.63 mL
1 mM 3.18 mL 15.91 mL 31.82 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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