HW091077

Name: HW091077
Brand: Adooq Bioscience
SKU: A67936
Rating: 5 (288 reviews)

Catalog No.: A67936

P2X3 Receptor Antagonist

HW091077 is a selective antagonist of the P2X3 receptor, exhibiting an IC50 of 17 nM. By inhibiting ATP-induced calcium influx and preventing cell depolarization, HW091077 effectively disrupts cough reflex pathways. This compound holds potential for research applications focused on chronic cough mechanisms.

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HW091077 2766757-56-4 P2X3 Receptor Antagonist

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Biological Activity

Description	HW091077 is a selective antagonist of the P2X3 receptor, exhibiting an IC50 of 17 nM. By inhibiting ATP-induced calcium influx and preventing cell depolarization, HW091077 effectively disrupts cough reflex pathways. This compound holds potential for research applications focused on chronic cough mechanisms.

Product Information

Catalog Num	A67936
Formula	C22H22F4N4O3S
Molecular Weight	498.49
CAS Number	2766757-56-4
SMILES	FC1=C(C2=NC=C(C)S2)C=C(C=C1C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)O[C@@H](C)[C@@H](O)C

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