INT-767

Catalog No.: A21494

dual FXR/TGR5 agonist

INT-767

INT-767 Chemical Structure

CAS NO. 1000403-03-1

INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$810.00
10 mg
$1,395.00
50 mg
$4,140.00
100 mg
$8,280.00
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Biological Activity

INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.08 mL 202.16 mL
0.5 mM 4.04 mL 20.22 mL 40.43 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21494
Actions Agonist
CAS No. 1000403-03-1
Formula C25H43NaO6S
M. Wt 494.66
Purity >98%
Synonyms INT767, INT 767
SMILES C[[email protected]](CCOS(=O)([O-])=O)[[email protected]@]1([H])CC[[email protected]@]2([H])[[email protected]]3([H])[[email protected]](O)[[email protected]](CC)[[email protected]]4([H])C[[email protected]](O)CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]@]21C.[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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