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Biological Activity
INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.22 mL | 101.08 mL | 202.16 mL |
| 0.5 mM | 4.04 mL | 20.22 mL | 40.43 mL |
| 1 mM | 2.02 mL | 10.11 mL | 20.22 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
*The above data is based on the productmolecular weight 494.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21494 |
|---|---|
| Actions | Agonist |
| CAS No. | 1000403-03-1 |
| Formula | C25H43NaO6S |
| M. Wt | 494.66 |
| Purity | >98% |
| Synonyms | INT767, INT 767 |
| SMILES | C[[email protected]](CCOS(=O)([O-])=O)[[email protected]@]1([H])CC[[email protected]@]2([H])[[email protected]]3([H])[[email protected]](O)[[email protected]](CC)[[email protected]]4([H])C[[email protected]](O)CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]@]21C.[Na+] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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