Iso-PPADS tetrasodium

Catalog No.: A67919
P2X-Purinoceptor Antagonist
Iso-PPADS tetrasodium is a selective antagonist of the P2X purinoceptors, specifically targeting P2X1 and P2X3 receptors with IC50 values of 43 nM and 84 nM, respectively. This compound is known for its neuroprotective effects, particularly in the context of ventilator-induced brain injury (VIBI). Iso-PPADS tetrasodium is useful for researchers investigating purinergic signaling pathways and their implications in various neurological conditions.
Grouped product items
Size Price Stock Qty
5mg
$150.00
In stock
10mg
$245.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIso-PPADS tetrasodium is a selective antagonist of the P2X purinoceptors, specifically targeting P2X1 and P2X3 receptors with IC50 values of 43 nM and 84 nM, respectively. This compound is known for its neuroprotective effects, particularly in the context of ventilator-induced brain injury (VIBI). Iso-PPADS tetrasodium is useful for researchers investigating purinergic signaling pathways and their implications in various neurological conditions.
Product Information
Catalog NumA67919
FormulaC14H10N3Na4O12PS2
Molecular Weight599.30
CAS Number207572-67-6
SMILESO=S(C1=CC=C(S(=O)(O[Na])=O)C=C1/N=N/C2=NC(C)=C(O)C(C=O)=C2COP(O[Na])(O[Na])=O)(O[Na])=O
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