Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Pyridoxine-d5 hydrochloride is a deuterium-labeled form of pyridoxine hydrochloride, also known as Vitamin B6. This compound exhibits antioxidant properties and has been shown to modulate the Nrf-2/HO-1 signaling pathway in cellular models of Alzheimer's disease. Pyridoxine-d5 hydrochloride is valuable for research applications involving metabolic studies, bioanalysis, and tracing studies in pharmacokinetics. -
Stable Isotope
Estrone-13C2 is a stable isotope-labeled form of the endogenous estrogen hormone, Estrone (E1). This compound plays a crucial role in estrogen signaling pathways and is primarily synthesized in adipose tissue through the aromatization of androstenedione. Its applications include use in metabolic studies, hormone quantification, and the investigation of estrogen-related biological processes. Estrone-13C2 serves as a valuable tool for researchers studying endocrine functions and metabolic regulation. -
Stable Isotope
Calcitriol-d3 is a deuterium-labeled analogue of Calcitriol, the most active metabolite of vitamin D. As an agonist of the vitamin D receptor (VDR), Calcitriol-d3 is valuable for discerning the pharmacodynamics of vitamin D signaling pathways. Its applications include studies on calcium homeostasis, bone health, and research into the role of vitamin D in immune function and cancer biology. -
Stable Isotope
2,6-Dibromophenol-d3 is a stable isotope-labeled form of 2,6-Dibromophenol, a compound known to function as an endogenous metabolite. This deuterated compound serves as a valuable tracer in biological studies, enabling precise quantification and tracking of metabolic processes in various research applications. Its use in mass spectrometry facilitates improved analytical sensitivity and specificity, making it an essential tool for metabolic profiling and pharmacokinetic studies. -
Stable Isotope
N-Methylformamide-d5 is a deuterium-labeled derivative of N-Methylformamide, serving as a stable isotope in research applications. It is utilized in various scientific studies, including those involving metabolic pathways and molecular labeling. The incorporation of deuterium allows for enhanced detection and analysis in techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, facilitating precise investigations in chemical and biological research. -
Stable Isotope
3-Methyl-2-buten-1-ol-d6 is a deuterium-labeled variant of 3-Methyl-2-buten-1-ol, a stable isotope used in various biochemical studies. This compound serves as a valuable tool for metabolic research, as it is an endogenous metabolite found in pine trees and utilized in fragrance formulations. Additionally, 3-Methyl-2-buten-1-ol has shown the ability to cross cell membranes and may influence body weight regulation, as evidenced by studies in animal models. Its isotopic labeling allows for enhanced tracing and quantification in metabolic pathways. -
Stable Isotope
2-Hydroxyhexanoic acid-d3 is a deuterium-labeled analogue of 2-Hydroxyhexanoic acid, serving as a stable isotope for research applications. As an endogenous metabolite, 2-Hydroxyhexanoic acid plays a role in metabolic pathways and lipid metabolism. The stable isotope labeling enables precise quantification and tracking of metabolic processes in biochemical studies. This compound is suitable for use in tracer studies and metabolic flux analysis. -
Stable Isotope
Indole-d4 is a deuterium-labeled derivative of indole, serving as a stable isotope for scientific research. This aromatic, heterocyclic organic compound is prevalent in nature and produced by numerous bacterial species. Indole plays a critical role in regulating multiple facets of bacterial physiology, including spore formation, plasmid stability, drug resistance, biofilm development, and virulence, acting as an important intercellular signaling molecule. Indole-d4 is valuable for studies involving metabolomics, microbial interaction, and bacterial signaling pathways. -
Stable Isotope
L-Alloisoleucine-d10 is a deuterium-labeled derivative of the branched-chain amino acid L-Alloisoleucine, an isomer of L-isoleucine. This stable isotope is valuable for metabolic studies and tracer experiments, allowing for the investigation of amino acid metabolism and protein synthesis in biological systems. Its presence in human plasma, albeit at low concentrations, makes it relevant for research in nutrition and metabolic disorders. -
Stable Isotope
L-Hexanoylcarnitine-d9 is a deuterium-labeled derivative of L-Hexanoylcarnitine, an acylcarnitine compound. This reagent is primarily utilized in stable isotope labeling studies, facilitating the investigation of metabolic pathways. Its relevance in research includes studies related to celiac disease and other metabolic disorders, providing valuable insights into carnitine metabolism and related biochemical processes. -
Stable Isotope
Isovalerylcarnitine-d9 chloride is a stable isotope-labeled derivative of Isovalerylcarnitine, functioning primarily as a tracer in metabolic studies. This compound is involved in the catabolism of L-leucine and serves as a potent activator of calpain, a calcium-dependent proteinase found in human neutrophils. Its use is essential in research applications focused on protein degradation pathways, cellular signaling, and the metabolic effects of amino acids. -
Stable Isotope
Ethyl 3-methyl-2-butenoate-d6 is a stable isotope-labeled derivative of Ethyl 3-methyl-2-butenoate. This deuterated compound serves as a valuable internal standard in quantitative analysis and metabolic studies. It provides enhanced sensitivity for tracing metabolic pathways and studying the dynamics of volatile compounds in various biological systems. Researchers can utilize this reagent to gain insights into metabolic processes and compound behavior in various experimental contexts. -
Stable Isotope
2-Ethylpyrazine-d5 is a deuterium-labeled derivative of 2-Ethylpyrazine, functioning as a stable isotope. This compound serves as a valuable tracer in metabolic studies, enabling researchers to investigate metabolic pathways and the behavior of pyrazine compounds in biological systems. Its use in mass spectrometry facilitates the quantification of metabolites and enhances the accuracy of research in pharmacokinetics and biochemistry. -
Stable Isotope
Cyromazine-13C3 is the carbon-13 labeled form of Cyromazine, a triazine insect growth regulator that functions as both an insecticide and acaricide. This compound specifically targets the nervous system of immature larval stages in various insect species, disrupting their growth and development. It is employed in research applications to study insect physiology, pest control strategies, and the environmental fate of insect growth regulators. -
Stable Isotope
2-(1-Piperazinyl)pyrimidine-d8 is a deuterium-labeled derivative of 2-(1-Piperazinyl)pyrimidine, designed for use as a stable isotope in various research applications. This compound can be employed in mechanistic studies, drug metabolism investigations, and chemical tracing experiments, providing enhanced accuracy in quantitative analyses. Its stable isotopic composition allows for improved sensitivity in mass spectrometry and nuclear magnetic resonance (NMR) studies. -
Stable Isotope
D-Fructose-5-13C is a stable isotope-labeled form of D-Fructose, a naturally occurring monosaccharide found in various plants. This isotope-labeled compound is utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and cellular processes. D-Fructose-5-13C serves as a valuable tool in biochemical research, enabling precise tracking of metabolic pathways and the role of fructose in biological systems. -
Stable Isotope
Dihydrouracil-13C,15N2 is a stable isotope-labeled form of Dihydrouracil, specifically incorporating 13C and 15N isotopes. This compound serves as a valuable marker for the detection of dihydropyrimidine dehydrogenase (DPD) deficiency, facilitating studies in pyrimidine metabolism. Its precise labeling enables enhanced tracking and evaluation in biochemical research applications, particularly in drug metabolism and pharmacogenomics. -
Stable Isotope
Bisphenol A-d8 is a deuterated analog of Bisphenol A, primarily utilized as a stable isotope in scientific research. This compound serves as a critical tool for studying metabolic pathways and exposure assessments related to Bisphenol A, which is recognized for its endocrine-disrupting properties. Bisphenol A has been linked to various health issues, including reproductive and developmental toxicity, obesity, and metabolic disorders. Researchers can employ Bisphenol A-d8 in mass spectrometry and tracer studies to enhance the understanding of its biological impact and environmental persistence. -
Stable Isotope
D-Glucose-13C,d is a stable isotope-labeled form of D-Glucose, featuring both deuterium and carbon-13. As a fundamental monosaccharide, D-Glucose plays a pivotal role in cellular metabolism and serves as an essential source of energy. This reagent is particularly valuable for metabolic studies, tracing glucose metabolism in various biological processes, and providing insights into carbohydrate utilization in both healthy and diseased states. -
Stable Isotope
Thyroxine hydrochloride-13C6 is a stable isotope-labeled form of L-Thyroxine (Levothyroxine; T4), designed for metabolic and physiological studies. As a synthetic thyroid hormone, it is crucial for investigating the mechanisms associated with hypothyroidism. This compound serves as a substrate for deiodinase enzymes, facilitating the conversion of L-Thyroxine (T4) into the biologically active form, Triiodothyronine (T3), making it valuable for research into thyroid hormone metabolism and regulation. -
2,6-Diaminoheptanedioic Acid Isotope
2,6-Diaminoheptanedioic Acid-13C7 is a stable isotope-labeled version of 2,6-Diaminoheptanedioic acid, a naturally occurring metabolite. This compound serves as a valuable tool in metabolic studies and tracer experiments, enabling precise tracking of metabolic pathways involving amino acid synthesis and degradation. Its incorporation of the 13C isotope allows for enhanced analytical detection and quantification in various biological research applications. -
Stable Isotope
D-Lyxose-13C-3 is a stable isotope-labeled derivative of D-Lyxose, an endogenous pentose sugar. This compound serves as a valuable precursor in the synthesis of various pharmaceutical agents, including anti-tumor drugs and L-nucleoside analogs with antiviral properties. Additionally, D-Lyxose-13C-3 can act as a synthetic intermediate for the preparation of other rare sugars, such as L-ribose, making it useful in chemical research and drug development applications. -
Stable Isotope
1,5-Anhydrosorbitol-13C6 is a stable isotope-labeled form of 1,5-Anhydrosorbitol, specifically designated for use in metabolic studies. As a recognized short-term marker for glycemic control, this compound facilitates precise tracking of carbohydrate metabolism in biological research. Its stable isotope labeling enhances accuracy in quantification and analysis of glucose metabolism, making it suitable for various biochemical assays and metabolic studies. -
Stable Isotope
3-Hydroxybutanoic acid-13C sodium is a stable isotope-labeled form of 3-Hydroxybutanoic acid sodium, serving as a vital metabolic intermediate. This compound is particularly relevant in the study of type I diabetes, where it is found in elevated levels. 3-Hydroxybutyric acid sodium is known to influence the properties of membrane lipids, making it valuable for research applications related to metabolic disorders and lipid membrane dynamics. -
Stable Isotope
Propane-1,1,2-d3-1,2-diol is a deuterium-labeled variant of (±)-1,2-Propanediol, a widely utilized aliphatic alcohol. Its primary function is to enhance the solubility and stability of active compounds in various molecular preparations. Research indicates that (±)-1,2-propanediol may influence neurobehavioral outcomes in zebrafish, making this reagent valuable for studies in neurobiology and pharmacokinetics. -
Stable Isotope
DL-Mevalonolactone-d4 is a stable isotope labeled analog of DL-Mevalonolactone, which serves as a precursor in the mevalonate pathway. It functions by inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), making it a valuable tool for studying statin-related myopathy and metabolic disorders. Additionally, DL-Mevalonolactone-d4 has been shown to induce inflammation and oxidative stress responses, affecting mitochondrial function and dynamics, thus providing insights into mitochondrial biology and pathophysiology. -
Stable Isotope
Propionyl CoA-d5 is a deuterium-labeled form of Propionyl CoA, an essential coenzyme in metabolic pathways. It acts as a key intermediate in the catabolism of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2. Additionally, Propionyl CoA serves as a substrate for the 2-methylcitrate synthase (PrpC) enzyme, facilitating the synthesis of 2-methylcitrate. This stable isotope is valuable for studies involving metabolic flux analysis and enzyme kinetics. -
Stable Isotope
L-Tyrosine-d1 is a deuterium-labeled form of L-Tyrosine, a non-essential amino acid that serves as a precursor to neurotransmitters such as dopamine, norepinephrine, and epinephrine. This stable isotope is primarily used in metabolic studies and tracer experiments to investigate amino acid metabolism and neurotransmitter synthesis. Additionally, L-Tyrosine-d1 can inhibit citrate synthase activity, enabling researchers to explore its effects in metabolic pathways, particularly in the nervous system. -
Stable Isotope
D-Fructose-6-13C is a stable isotope-labeled form of D-Fructose, specifically incorporating carbon-13 at the sixth position. As a naturally occurring monosaccharide, D-Fructose plays a crucial role in carbohydrate metabolism and energy production in various biological systems. This stable isotope can be utilized in metabolic studies, tracer studies, and for understanding carbohydrate dynamics in research applications involving plant and animal physiology. -
Stable Isotope
D-Galactose-d2 is a deuterium-labeled form of D-Galactose, a natural aldohexose and C-4 epimer of glucose. This stable isotope is commonly utilized in metabolic studies, isotopic tracing, and biochemical research to elucidate carbohydrate metabolism and its role in cellular processes. D-Galactose-d2 serves as a valuable tool for understanding the physiological effects of galactose and its conversion pathways in various biological systems. -
Stable Isotope
Xylose-13C2 is a stable isotope-labeled form of D-(+)-Xylose, a natural pentose sugar. It serves as a substrate for xylose isomerase, facilitating the conversion into xylulose, a crucial intermediate in the anaerobic fermentation processes of xylose. This compound supports research applications in the production of biofuels, chemicals, and industrial enzymes, enabling the exploration of lignocellulosic biomass resources. Xylose-13C2 provides essential carbon sources for microbial biosynthesis of high-value products, contributing to advancements in metabolic engineering and fermentation technologies. -
Stable Isotope
N-Acetyl-D-glucosamine-2-13C is a stable isotope-labeled form of N-Acetyl-D-glucosamine, a monosaccharide derivative of glucose. This compound serves as a valuable tracer in metabolic studies, enabling researchers to investigate carbohydrate metabolism and glycosylation processes in various biological systems. Its unique isotopic signature facilitates advanced analytical techniques such as NMR spectroscopy and mass spectrometry in biochemical research. -
Stable Isotope
DPPC-d13 is a deuterium-labeled form of dioleoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This stable isotope is utilized in the preparation of liposomal monolayers, facilitating the study of lipid interactions and dynamics. DPPC-d13 liposomes are particularly effective in serving as delivery vehicles for inducing immune responses against glycosphingolipid (GSL) antigens, making it a valuable tool for immunological research and drug delivery applications. -
Stable Isotope
1-Dodecanol-d1 is a deuterium-labeled form of 1-Dodecanol, serving as a stable isotope. This compound is an endogenous metabolite involved in various biological processes, making it valuable for metabolic studies and tracing applications. Its isotopic labeling provides a useful tool for researchers investigating lipid metabolism and biochemical pathways. -
Stable Isotope
D-Fructose-d2 is a deuterium-labeled derivative of D-Fructose, a naturally occurring monosaccharide prevalent in various plants. This stable isotope is essential for metabolic studies and provides valuable insights into carbohydrate metabolism. It is widely utilized in isotopic labeling experiments to trace metabolic pathways and investigate the biological activity of fructose in different biological systems. -
Stable Isotope
1-Hexadecanol-d31 is a deuterium-labeled variant of 1-Hexadecanol, a long-chain fatty alcohol. Its stable isotope nature makes it a valuable tool for various analytical applications, including lipid metabolism studies and fatty acid profiling. Researchers utilize 1-Hexadecanol-d31 to investigate metabolic pathways, trace lipid incorporation, and enhance the understanding of lipophilic substrates in biochemical research. -
Stable Isotope
D-Ribose-13C-2 is a stable isotope-labeled form of D-Ribose, which plays a critical role in energy production as a precursor of ATP. This compound is utilized in metabolic research, particularly in studies focused on energy metabolism, chronic fatigue syndrome, and cardiac function. Its ability to participate in protein glycosylation further supports its application in various biomedical research areas. -
Stable Isotope
D-Galactose-13C-3 is a stable isotope-labeled form of D-Galactose, an aldohexose that serves as a C-4 epimer of glucose. As a labeled reagent, it is utilized in metabolic studies, including research on carbohydrate metabolism and flux analysis in various biological systems. Its incorporation into metabolic pathways allows for enhanced tracking of biological processes involving galactose metabolism. -
Stable Isotope
Hydroxy Bosentan-d4 is a deuterium-labeled derivative of Hydroxy bosentan, a primary metabolite of Bosentan (BOS) that undergoes metabolism via the cytochrome P450 system in the liver. This isotope-labeled compound maintains 10%-20% of BOS's pharmacological activity, making it valuable for studying the metabolism and pharmacokinetics of Bosentan in various biological systems. Hydroxy Bosentan-d4 is suitable for applications in drug metabolism research and isotope labeling studies. -
Stable Isotope
3β,7α-Dihydroxycholest-5-enoic acid-d3 is a stable isotope-labeled analog of 3β,7α-Dihydroxycholest-5-enoic acid. This compound serves as a valuable tool for metabolic studies and tracer applications. Its deuterium labeling allows for enhanced detection and quantification in various biological assays, facilitating research in lipid metabolism and cholesterol regulation. -
Stable Isotope
Pentane-1,5-diamine-15N2 dihydrochloride is a stable isotope-labeled derivative of Pentane-1,5-diamine dihydrochloride. This compound serves as an important tool in metabolic studies and tracer experiments, allowing researchers to track nitrogen incorporation and metabolism in biological systems. Its use enhances the precision of analytical techniques in various biochemical research applications. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-d9-1 is a deuterated form of Propane-1,2,3-triyl tripalmitate, serving as a stable isotope. This compound is an endogenous metabolite that can be utilized in metabolic studies and tracer experiments to investigate lipid metabolism and biological pathways. Its stable isotope labeling enables precise quantification and tracking within biological systems, making it a valuable reagent for biochemical and pharmacokinetic research applications. -
Stable Isotope
3b-Hydroxy-5-cholenoic acid-d4 is a deuterated analog of 3b-Hydroxy-5-cholenoic acid, serving as a stable isotope for biochemical studies. This monohydroxy bile acid, derived from endogenous pathways, plays a crucial role in lipid metabolism and bile acid synthesis. It is utilized in research applications involving metabolic profiling, pharmacokinetics, and the study of bile acid regulation within physiological and pathological processes. -
Stable Isotope
L-Aspartic acid-13C4,15N,d3 is a stable isotope-labeled form of L-Aspartic acid, incorporating deuterium and 13C and 15N isotopes. As a naturally occurring amino acid, it has the ability to penetrate the blood-brain barrier and is utilized in the development of prodrugs targeting colon and cecal tissues. This compound is valuable in research related to inflammatory conditions and metabolic studies, providing insights into amino acid metabolism and biochemical pathways. -
Stable Isotope
L-Proline-13C5,15N,d7 is a stable isotope-labeled derivative of L-Proline, incorporating deuterium, carbon-13, and nitrogen-15. L-Proline is a key amino acid involved in protein synthesis and various metabolic processes in living organisms. This isotopically labeled compound is valuable for applications in metabolic tracing studies, NMR spectroscopy, and understanding protein dynamics. -
Stable Isotope
Tetrahydrocortisone-d5-1 is a deuterium-labeled analog of Tetrahydrocortisone, a hormone involved in stress response. This stable isotope form is useful for metabolic studies and tracing experiments related to glucocorticoid metabolism. It serves as an important tool for researchers studying the biochemistry and physiological effects of corticosteroids in various biological contexts. -
Stable Isotope
N-Methylformamide-d1 is a deuterated isotope of N-Methylformamide, designed for use in various chemical and biological research applications. This stable isotope is primarily utilized in NMR spectroscopy and mass spectrometry to gain insights into molecular structures and dynamics. It serves as a valuable tool in the study of chemical reactions and mechanisms, enhancing the accuracy of experimental results in both synthetic and analytical chemistry. -
Stable Isotope
N-Methylformamide-d4 is a deuterated form of N-Methylformamide, serving as a stable isotope for various analytical applications. This compound is commonly utilized in NMR spectroscopy and mass spectrometry to study biochemical pathways and molecular interactions. Its isotopic labeling facilitates tracking and quantification in metabolic studies, enabling advanced research in chemical biology and related fields. -
Stable Isotope
DL-Glyceraldehyde-2-13C is a stable isotope-labeled form of DL-Glyceraldehyde. This compound is primarily utilized in metabolic studies as a tracer to investigate carbohydrate metabolism and glycolytic pathways. Its incorporation into biological systems allows for enhanced tracking and quantification of metabolic fluxes in various research applications, including cellular metabolism and biochemical assays. -
Stable Isotope
Cyromazine-d4 is a deuterated form of the insect growth regulator cyromazine, belonging to the triazine chemical class. It primarily acts as an insecticide and acaricide, targeting the nervous system of immature larval stages of specific insect species. This stable isotope is essential for research applications involving trace analysis and metabolic studies of cyromazine's biological effects.
