Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
2-Hydroxyisobutyric acid-d6 is a deuterated form of 2-Hydroxyisobutyric acid, serving as a stable isotope for metabolic studies. This compound is an endogenous metabolite that plays a role in cellular energy metabolism and has been implicated in various biochemical pathways. Its unique isotopic labeling facilitates detailed investigations into metabolic flux and labeling experiments in biological systems. Researchers can utilize 2-Hydroxyisobutyric acid-d6 for studies in metabolic disease, bioenergetics, and related fields. -
Stable Isotope
Fumaric acid-d2 is a deuterated form of fumaric acid, serving as a stable isotope label for metabolic studies. This compound is implicated in fumarase deficiency and functions as an oncometabolite, which is associated with cancer pathogenesis. Fumaric acid-d2 is valuable for research applications involving metabolic profiling and the study of cancer metabolism. -
Stable Isotope
L-Cysteine-15N is a stable isotope-labeled form of L-Cysteine, a conditionally essential amino acid. This compound serves as a precursor for key biological molecules, including hydrogen sulfide (H2S), glutathione, and taurine. L-Cysteine-15N is utilized in research to investigate metabolic pathways and the modulation of appetite, as it has been shown to suppress ghrelin levels in various biological systems. -
Stable Isotope
Neopterin-13C5 is a stable isotope-labeled form of neopterin, specifically deuterium-labeled D-(+)-neopterin. As a catabolic product of guanosine triphosphate (GTP), neopterin serves as a significant biomarker for cellular immune system activation. This compound is valuable for research applications involving immunological responses, biochemistry, and metabolic pathways, facilitating deeper insights into immune system dynamics. -
Stable Isotope
Bisphenol A-d6 is the deuterated form of Bisphenol A, a synthetic phenolic compound primarily utilized in the manufacturing of polycarbonate plastics and epoxy resins. This stable isotope is valuable for studying the compound's metabolic pathways and environmental fate due to its role as an endocrine-disrupting compound (EDC). Research indicates that Bisphenol A is linked to various health issues, including reproductive disorders, cardiovascular diseases, diabetes, and obesity, making it a critical target for toxicological studies and environmental assessments. -
Stable Isotope
L-Threonine-d5 is a stable isotope-labeled form of the amino acid L-Threonine. This compound serves as a valuable tracer in metabolic studies, allowing for precise quantification and tracking of L-Threonine in biological systems. It is widely utilized in research applications related to nutritional studies, amino acid metabolism, and microbial fermentation processes. -
Stable Isotope
Levoglucosan-d7 is a deuterium-labeled derivative of levoglucosan, a 1,6-anhydro-β-D-glucopyranose produced through the pyrolysis of glucans. This stable isotope is utilized in environmental research, particularly in studies examining biomass combustion and its byproducts. Levoglucosan-d7 serves as a useful tracer for investigating atmospheric processes and biogeochemical cycling related to organic matter. -
Stable Isotope
Myristic acid-d3 is a deuterium-labeled derivative of myristic acid, a saturated 14-carbon fatty acid found in various animal and vegetable fats, notably in butterfat, coconut oil, palm oil, and nutmeg oil. As a stable isotope reagent, myristic acid-d3 is utilized in metabolic studies and tracer experiments to investigate fatty acid metabolism and lipid profiles. It is essential for research involving lipid biochemistry and tracing metabolic pathways in biological systems. -
Stable Isotope
DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is a stable isotope-labeled form of DL-Homocystine, featuring deuterium substitution at specific positions. DL-Homocystine, a dimeric form of homocysteine, plays a significant role in the study of neurobiological conditions, particularly in relation to the pathogenesis and pathophysiology of schizophrenia. This reagent is valuable for research applications involving metabolic tracking and biochemical analysis of sulfur-containing amino acids, facilitating insights into neural dysfunction and related disorders. -
Stable Isotope
Methylmalonic acid-13C4 is a stable isotope-labeled form of Methylmalonic acid, useful for tracing metabolic pathways. This compound serves as a biomarker for Vitamin B-12 deficiency, particularly relevant in cancer research. It aids in evaluating metabolic disruptions associated with deficiencies and can be utilized in studies involving metabolic profiling and nutritional assessment. -
Stable Isotope
Pyridoxine-d2 hydrochloride is a deuterium-labeled derivative of Pyridoxine hydrochloride, a compound belonging to the pyridine class. This stable isotope serves as an invaluable tool in metabolic studies and tracer experiments. Pyridoxine (Vitamin B6) demonstrates antioxidant properties in cellular models of Alzheimer's disease, primarily through the Nrf-2/HO-1 signaling pathway, making it relevant for research into neurodegenerative disorders. -
Stable Isotope
Estradiol-d3 is a deuterium-labeled analog of the steroid sex hormone estradiol. This stable isotope is essential for studying estradiol's role in fertility and secondary sexual characteristics in females. Estradiol-d3 is commonly used in research to investigate IL-6 expression regulation via the estrogen receptor β (ERβ) pathway, providing valuable insights into hormonal signaling and related biological processes. -
Stable Isotope
D-Ribose (mixture of isomers)-13C5 is a stable isotope-labeled form of D-Ribose, which serves as a crucial sugar moiety in adenosine triphosphate (ATP) production. It functions as an energy enhancer and is commonly employed in metabolic therapy for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Additionally, D-Ribose is involved in protein glycation and can stimulate NF-κB-dependent inflammation through the receptor for advanced glycation end-products (RAGE). This makes it a valuable tool for research in metabolic and inflammatory pathways. -
Stable Isotope
C16-Ceramide-d31 is a deuterated form of C16-Ceramide, functioning as a stable isotope. This compound is essential for studying ceramide metabolism and signaling pathways in biological systems. Its stable isotope labeling enables precise tracking and quantification in mass spectrometry applications, making it valuable for research on lipid biology, cell signaling, and neurobiology. -
Stable Isotope
Isovaleric acid-d7 is a deuterated form of isovaleric acid, functioning as a stable isotope for tracers in metabolic studies. It is recognized for its role in various biological processes and has been associated with neonatal health concerns and Jamaican vomiting sickness in humans. This reagent is valuable in analytical research, particularly in studies involving fatty acid metabolism and its physiological impacts. -
Stable Isotope
Docosahexaenoic acid-d5 is a deuterium-labeled derivative of docosahexaenoic acid (DHA), an omega-3 fatty acid primarily found in brain and retinal tissues. This stable isotope is useful in metabolic studies and tracer experiments, allowing for the investigation of lipid metabolism and the role of DHA in neurological health. Its application extends to research on dietary impacts and fatty acid supplementation in various biological systems. -
Stable Isotope
D-Sorbitol-d8 is a deuterium-labeled derivative of D-Sorbitol, a six-carbon sugar alcohol. This stable isotope is utilized in various research applications, particularly in metabolic studies and tracer experiments. D-Sorbitol serves as a sweetener, humectant, and thickening agent, making it valuable as an excipient and dietary supplement in pharmaceutical formulations. Its deuterium labeling enhances the understanding of biological pathways and kinetics in chemical research. -
Stable Isotope
Cholesterol-d4 is a deuterium-labeled analog of cholesterol, which serves as a stable isotope. Cholesterol is a critical structural component of mammalian plasma membranes, constituting 20-25% of their composition. It significantly influences membrane fluidity and permeability, impacting the functionality of transporters and signaling proteins. Additionally, cholesterol acts as an endogenous agonist for the estrogen-related receptor α (ERRα), making Cholesterol-d4 a valuable tool in research focusing on membrane dynamics and receptor interactions. -
Stable Isotope
L-Tyrosine-15N is a stable isotope-labeled form of L-Tyrosine, a non-essential amino acid. It serves as a valuable tool for metabolic studies and tracer experiments due to its incorporation into proteins and other biomolecules. Its unique isotopic signature allows for the investigation of amino acid metabolism and its effects on various biological processes, making it essential for research in neurobiology and metabolic pathways. -
Stable Isotope
L-Methionine-d8 is a deuterated form of the essential amino acid L-Methionine, which plays a crucial role in human development and liver protection. This stable isotope is valuable in metabolic studies, allowing for more accurate tracking of amino acid metabolism in various biological systems. L-Methionine-d8 can be utilized in research involving nutritional sciences, pharmacology, and toxicology to better understand the dynamics of methionine in physiological processes. -
Stable Isotope
L-Alanine-15N is the isotopically labeled form of L-Alanine, incorporating the stable isotope nitrogen-15. As a non-essential amino acid, L-Alanine plays a crucial role in metabolic processes, contributing to energy production in muscle tissue, the brain, and the central nervous system. This reagent is valuable for research applications in metabolic studies and tracer experiments, facilitating the investigation of amino acid metabolism and its effects on cellular functions and immunity. -
Stable Isotope
Heptadecanoic acid-d3 is a deuterium-labeled derivative of heptadecanoic acid, an odd-chain saturated fatty acid. This compound serves as a stable isotope marker, facilitating studies on lipid metabolism and fatty acid profiling. Research indicates a correlation between heptadecanoic acid levels and metabolic disorders, including coronary heart disease, prediabetes, type 2 diabetes, and multiple sclerosis, making it valuable for investigating disease mechanisms and potential therapeutic targets. -
Stable Isotope
L-Aspartic acid-13C4,15N is a stable isotope-labeled form of L-Aspartic acid, featuring both carbon-13 and nitrogen-15 isotopes. This amino acid is capable of penetrating the blood-brain barrier and is often utilized in the development of prodrugs aimed at colon and cecal tissues. L-Aspartic acid also plays a significant role in the investigation of inflammatory conditions, serving as a valuable tool in metabolic and biochemical research. -
Stable Isotope
Creatine-13C is a stable isotope-labeled form of creatine, an endogenous derivative of amino acids. It is integral to cellular energy metabolism, particularly in muscle and brain tissues. This reagent is widely used in metabolic studies, tracer experiments, and research focusing on energy dynamics and muscle physiology. -
Stable Isotope
5-Hydroxyindole-3-acetic acid-d2 is a deuterium-labeled form of 5-hydroxyindole-3-acetic acid, a key metabolite of serotonin. This stable isotope is utilized in research to accurately quantify serotonin metabolism and assess neuroendocrine tumor markers. Its unique labeling allows for advanced analytical techniques, making it valuable in biochemical and pharmacological studies. -
Stable Isotope
Tetranor-PGEM-d6 is a deuterated stable isotope derivative of tetranor-PGEM, designed for use in mass spectrometry and biochemical studies. This compound provides researchers with a valuable tool for the quantitative analysis of prostaglandin metabolites and their pathways. Its incorporation of deuterium allows for enhanced sensitivity and specificity in tracking metabolic processes, making it an essential reagent for studies involving lipid signaling and inflammation research. -
Stable Isotope
Arachidonic acid-d11 is a deuterium-labeled form of arachidonic acid, an essential fatty acid integral to cell membrane structure and function. This stable isotope is widely utilized in biochemical research to study complex lipid signaling pathways, including those involved in inflammation and cellular signaling. Its application in mass spectrometry enables precise quantification of arachidonic acid metabolism in various biological systems. -
Stable Isotope
Hypoxanthine-13C5 is a stable isotope-labeled form of hypoxanthine, a purine derivative. It serves as a potential free radical generator and can be utilized as an indicator of hypoxic conditions in biological research. This reagent is valuable for studies investigating cellular metabolism, hypoxia-related pathways, and the effects of reactive oxygen species in various physiological contexts. -
Stable Isotope
Cytosine-d2 is a stable isotope-labeled form of cytosine, one of the four principal nucleobases in DNA and RNA. The deuterium substitution enhances its utility in various analytical techniques, especially in studies of epigenetic modifications. This reagent is particularly valuable for investigating circadian oscillations of cytosine modifications, contributing to the understanding of epigenetic diversity and aging processes. -
Stable Isotope
D-Leucine-d10 is a deuterium-labeled variant of D-Leucine, known for its enhanced potency as an anti-seizure compound compared to its L-leucine counterpart. This stable isotope effectively terminates seizure activity even after it has commenced and is recognized for its ability to reduce long-term potentiation without affecting basal synaptic transmission in vitro. D-Leucine-d10 is valuable for research applications involving seizure mechanisms and synaptic plasticity studies. -
Stable Isotope
Lignoceric acid-d47 is a deuterium-labeled derivative of Lignoceric acid, a saturated fatty acid with a chain length of 24 carbons (24:0). This stable isotope is primarily utilized for tracer studies in metabolic research. Lignoceric acid plays a crucial role in neurodevelopment and is implicated in disorders such as Zellweger syndrome and adrenoleukodystrophy, making this labeled form valuable for studying these conditions at a molecular level. -
Stable Isotope
5-Hydroxyindole-3-acetic acid-d5 is a deuterium-labeled form of 5-Hydroxyindole-3-acetic acid, primarily used as a stable isotope. As a significant metabolite of serotonin, it serves as an important biomarker for neuroendocrine tumors. This reagent is essential for analytical studies involving metabolic pathways and biomarker identification in various research applications. -
Stable Isotope
3-Hydroxybutyric acid-13C4 sodium is a stable isotope-labeled form of 3-Hydroxybutyric acid, a key metabolite involved in lipid metabolism. This compound is particularly relevant in the study of type I diabetes, where its levels are often elevated, and it has the potential to influence the properties of membrane lipids. Research applications include metabolic studies and investigations into the biochemical pathways associated with diabetes and lipid metabolism. -
Stable Isotope
L-Ornithine-15N2 hydrochloride is a stable isotope-labeled form of the amino acid L-Ornithine, which is crucial in the urea cycle and nitrogen metabolism. This reagent is primarily used in metabolic studies and tracer experiments to investigate nitrogen sources and amino acid dynamics in biological systems. Its isotopic labeling allows for precise tracking of L-Ornithine in various research applications, including nutrition and biochemical pathways. -
Stable Isotope
2-Ketoglutaric acid-d6 is a stable isotope-labeled form of 2-Ketoglutaric acid, a key intermediate in the Krebs cycle responsible for ATP and GTP production. This compound plays a vital role in nitrogen assimilation processes and serves as a substrate for various biosynthetic pathways. Additionally, 2-Ketoglutaric acid-d6 exhibits properties as a reversible inhibitor of tyrosinase, making it useful for studies related to enzymatic regulation and metabolic pathways. This reagent is ideal for use in metabolic labeling experiments and kinetic studies in biochemical research. -
Stable Isotope
DL-Aspartic acid-d3 is a deuterated form of L-Aspartic acid, an amino acid known for its ability to traverse the blood-brain barrier. This stable isotope serves as a valuable tool in metabolic studies and is particularly beneficial in researching inflammatory conditions and preparing prodrugs aimed at colon and cecal tissues. Its unique labeling allows for precise tracking and quantification in biological systems, enhancing its application in biochemical research. -
Stable Isotope
L-Threonine-13C4,15N is a stable isotope-labeled form of the natural amino acid L-Threonine, incorporating four carbon-13 atoms and one nitrogen-15 atom. This compound is valuable for metabolic studies and isotopic tracing in biochemical research. Its applications include investigating protein synthesis, metabolic pathways, and amino acid utilization in various biological systems. L-Threonine-13C4,15N is suitable for enhancing the precision of analyses in food, pharmaceutical, and nutritional studies. -
Stable Isotope
Hypoxanthine-d2 is a deuterium-labeled derivative of hypoxanthine, serving as a stable isotope for research applications. As a purine metabolite, hypoxanthine-d2 can act as a potential free radical generator, making it useful for studies related to oxidative stress and hypoxia. Its incorporation in metabolic research allows for the tracing of pathways in cellular metabolism and the evaluation of hypoxic conditions in biological systems. -
Stable Isotope
(R)-3-Hydroxybutanoic acid-13C2 sodium is a stable isotope-labeled form of (R)-3-hydroxybutanoic acid sodium, a metabolite derived from acetoacetic acid through the action of 3-hydroxybutyrate dehydrogenase. This compound serves as an important nutritional source and acts as a precursor for various biological molecules, including vitamins, antibiotics, and pheromones. It is widely used in metabolic studies and tracing experiments to understand metabolic pathways and compound utilization in biological systems. -
Stable Isotope
L-Alanine-d7 is a deuterium-labeled stable isotope of L-Alanine, a non-essential amino acid. This compound plays a crucial role in sugar and acid metabolism and is known to enhance immune function while supplying energy to muscle tissue, the brain, and the central nervous system. L-Alanine-d7 is valuable in metabolic research, tracer studies, and isotopic labeling applications, enabling precise analysis of biochemical pathways. -
Stable Isotope
Suberic acid-d4 is a deuterium-labeled derivative of suberic acid (octanedioic acid), a dicarboxylic acid that plays a role in metabolic pathways. It is utilized as a stable isotope for isotopic tracing studies in metabolic research. Suberic acid is associated with carnitine-acylcarnitine translocase deficiency and malonyl-CoA decarboxylase deficiency, making this reagent valuable for studying these metabolic disorders and related biochemical processes. -
Stable Isotope
Stearic acid-d7 is the deuterium-labeled form of stearic acid, a saturated long-chain fatty acid commonly found in various animal and vegetable fats and oils. As a stable isotope, Stearic acid-d7 serves as a valuable tool in metabolic studies, aiding in the investigation of lipid metabolism and pathways. Its precise labeling allows for enhanced tracking in biological systems, making it suitable for applications in pharmacokinetics and metabolic flux analysis. -
Stable Isotope
L-Alanine-13C3 is a stable isotope-labeled form of the non-essential amino acid L-Alanine. This compound plays a crucial role in metabolic pathways, particularly in glucose and organic acid metabolism, and is essential for supporting immune function and energy production in muscle, brain, and central nervous systems. L-Alanine-13C3 is commonly utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and related physiological processes. -
Stable Isotope
Fumaric acid-d4 is a stable isotope-labeled form of fumaric acid, a key intermediate in the tricarboxylic acid (TCA) cycle. This compound is associated with fumarase deficiency and has been identified as an oncometabolite involved in cancer metabolism. Fumaric acid-d4 can be utilized in metabolic studies, tracer experiments, and research into the biochemical pathways related to cancer and metabolic disorders. -
Stable Isotope
L-Alanine-13C3,15N is a stable isotope-labeled form of the non-essential amino acid L-Alanine, featuring three carbon-13 isotopes and one nitrogen-15 isotope. L-Alanine plays a critical role in amino acid metabolism, enhances immune function, and serves as an energy source for muscle tissue, the brain, and the central nervous system. This reagent is widely applicable in metabolic flux studies, tracer experiments, and isotope labeling investigations in biochemical and clinical research. -
Stable Isotope
D-Galactose-d is the deuterium-labeled form of D-Galactose, a naturally occurring aldohexose and C-4 epimer of glucose. This stable isotope is primarily utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and cellular processes. Its incorporation into various biological systems allows for precise tracking of metabolic pathways, enhancing research in areas such as biochemistry, molecular biology, and nutritional science. -
Stable Isotope
Uracil-d1 is a deuterium-labeled derivative of uracil, a naturally occurring pyrimidine base and one of the four nucleobases found in RNA. This stable isotope-labeled compound is essential for research applications involving nucleic acid studies, particularly in the areas of RNA synthesis and metabolism. It serves as a valuable tool in tracking metabolic pathways and understanding RNA dynamics in various biological systems. -
Stable Isotope
D-Fructose-d-2 is a stable isotope-labeled variant of D-Fructose, a naturally occurring monosaccharide prevalent in various plants. This deuterium-labeled compound serves as a valuable tool in metabolic studies and isotopic tracing experiments. Its unique properties allow researchers to investigate carbohydrate metabolism and enzymatic pathways with enhanced analytical accuracy. -
Stable Isotope
meso-Erythritol-d6 is a deuterated form of meso-Erythritol, a sugar alcohol commonly present in many fruits, including pears and watermelons. This stable isotope can serve as a valuable tool in metabolic labeling studies and tracer experiments, allowing for the investigation of metabolic pathways involving sugar alcohols. Its sweetness is approximately 60-80% that of sucrose, making it suitable for use in low-calorie sweetener formulations. -
Stable Isotope
Estrone-13C3 is a stable isotope-labeled form of the natural estrogenic hormone estrone (E1). As a key endogenous estrogen, estrone plays a significant role in various physiological processes and is primarily produced in adipose tissue through the aromatization of androstenedione. This reagent is valuable in research applications involving hormone metabolism, endocrine studies, and the assessment of estrogenic activity in biological systems.
