Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Sodium 3-methyl-2-oxobutanoate-13C2,d4 is a stable isotope-labeled form of sodium 3-methyl-2-oxobutanoate, featuring deuterium and carbon-13 isotopes. This compound serves as a valuable tracer in metabolic studies, allowing researchers to investigate biochemical pathways and metabolic flux in various biological systems. Its application in NMR spectroscopy and mass spectrometry facilitates precise analyses of metabolic intermediates and enzymatic reactions in cellular models. -
Stable Isotope
L-Leucine-2-13C is a stable isotope-labeled form of the essential branched-chain amino acid L-Leucine. This compound plays a critical role in activating the mTOR signaling pathway, which is essential for protein synthesis and cell growth. It is commonly utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and protein turnover in various biological systems. -
Stable Isotope
m-Anisaldehyde-d3 is a deuterated form of m-Anisaldehyde, a stable isotope commonly utilized in chemical research. Known as 3-Methoxybenzaldehyde, this compound serves as an endogenous metabolite and has been linked to thyroid autoimmunity during early pregnancy. Its stable isotope nature allows for precise tracking and quantification in metabolic studies, making it valuable for research in pharmacokinetics and biomarker identification. -
Stable Isotope
Boc-Leu-OH·H2O-13C is a stable isotope-labeled derivative of N-Boc-L-leucine, featuring a carbon-13 (13C) label. This amino acid derivative, protected with a Boc group, serves as an essential building block for the synthesis of peptides, such as L-prolyl-L-leucyl-glycinamide, which exhibit modulatory activity on dopamine receptors. It is valuable for applications in peptide research, metabolic studies, and tracer experiments utilizing stable isotopes. -
Stable Isotope
Uracil-d2-1 is a deuterium-labeled form of uracil, a naturally occurring pyrimidine derivative and one of the four nucleobases found in RNA. This stable isotope is utilized in various biochemical and molecular biology research applications, particularly in studying RNA dynamics, metabolism, and synthesis. It serves as a valuable tool for tracing metabolic pathways and understanding nucleic acid behavior in different biological systems. -
Stable Isotope
2,3,5-Trimethylpyrazine-d9 is a deuterium-labeled derivative of 2,3,5-trimethylpyrazine, an endogenous metabolite. This stable isotope is utilized in metabolic studies and tracer experiments to investigate metabolic pathways and mechanisms in biological systems. Its unique isotopic signature enables precise quantification and tracking of metabolic processes, making it a valuable tool in chemical research and drug development. -
Stable Isotope
m-Coumaric acid-13C3 is a stable isotope-labeled derivative of m-Coumaric acid, a polyphenolic compound derived from caffeic acid. This metabolite is produced by gut microflora and its concentration in human biofluids varies based on dietary intake. This reagent is essential for studies involving metabolic tracing and biomarker discovery in nutritional and microbiome research. -
Stable Isotope
Arabinose-1-13C is a stable isotope-labeled form of arabinose, a naturally occurring monosaccharide. This compound serves as a valuable tracer in metabolic studies, enabling researchers to investigate carbohydrate metabolism and biosynthetic pathways. Arabinose-1-13C is particularly useful in applications involving metabolic flux analysis and provides insights into the physiological roles of arabinose in various biological systems. -
Stable Isotope
Suberic acid-d12 is a deuterium-labeled derivative of suberic acid, also known as octanedioic acid, functioning as a stable isotope. Its primary applications include metabolic studies and tracer experiments in biochemical research. This reagent is particularly relevant in investigating metabolic disorders such as carnitine-acylcarnitine translocase deficiency and malonyl-CoA decarboxylase deficiency, providing insight into fatty acid metabolism and related pathways. -
Stable Isotope
2-Ketoglutaric acid-13C2 is a stable isotope-labeled form of 2-ketoglutaric acid, which serves as a critical intermediate in the Krebs cycle for the production of ATP and GTP. Additionally, it plays a significant role as a carbon skeleton in nitrogen-assimilatory reactions. This compound has been identified as a reversible inhibitor of tyrosinase, with an IC50 of 15 mM, making it valuable for biochemical studies and metabolic research applications. -
Stable Isotope
D-Mannose-13C-1 is a stable isotope-labeled form of D-Mannose, a carbohydrate critical for human metabolism and the glycosylation of specific proteins. This reagent is utilized in research focused on metabolic pathways, glycoprotein biosynthesis, and the study of carbohydrate interactions in various biological systems. Its stable isotope composition allows for precise tracing and quantification in analytical applications. -
Stable Isotope
5-Methoxyindole-d3 is a deuterium-labeled derivative of 5-Methoxyindole, serving as a stable isotope for analytical applications. As an endogenous compound derived from L-tryptophan metabolism, it plays a crucial role in biological systems. This reagent can be utilized as a drug intermediate in the synthesis of 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, while also exhibiting notable anti-cancer and anti-inflammatory properties, making it valuable for research in pharmacology and disease mechanisms. -
Stable Isotope
1-Naphthol-d8 is a deuterium-labeled derivative of 1-Naphthol, designed as a stable isotope for research applications. This compound acts as an excited state proton transfer (ESPT) fluorescent molecular probe, enabling studies in photophysics and chemical dynamics. Its unique isotopic labeling allows for enhanced analytical sensitivity and specificity in various biochemical assays and investigations. -
Stable Isotope
Benzyl alcohol-α-13C-α,α-d2 is a stable isotope-labeled version of benzyl alcohol, an aromatic alcohol characterized by its colorless liquid form and mild, pleasant aroma. This reagent serves as a valuable tool in tracking metabolic pathways and conducting quantitative studies in various biological contexts. Its stable isotopic labeling allows for precise analysis in applications such as mass spectrometry and tracer studies in metabolic research. -
Stable Isotope
Phenylglyoxylic acid-13C8 is a stable isotope-labeled form of phenylglyoxylic acid, also known as benzoylformic acid. This compound is a significant metabolite of ethylbenzene and styrene, serving as a reliable biomarker for exposure to these substances in humans. In addition, phenylglyoxylic acid can be employed as an intermediate in the synthesis of antineoplastic agents, facilitating research in drug development and metabolic studies. -
Stable Isotope
C18:1 Ceramide-d7 is a deuterium-labeled derivative of C18:1 Ceramide, functioning as a stable isotope. This compound is primarily used for tracking and quantifying lipid metabolism in biological systems. Its incorporation into ceramide metabolism studies allows for enhanced analytical sensitivity in mass spectrometry applications, facilitating deeper insights into cellular signaling pathways and lipid-related diseases. -
Stable Isotope
α-Muricholic acid-d5 is a deuterium-labeled derivative of α-Muricholic acid, which serves as a stable isotope for research applications. As the predominant primary bile acid in rodents, α-Muricholic acid plays a critical role in lipid metabolism and gut physiology. This isotopically labeled compound can be utilized in studies investigating bile acid signaling pathways, metabolic processes, and the pharmacokinetics of bile acids within biological systems. -
Stable Isotope
L-Alanine-13C3,15N,d4 is a stable isotope-labeled form of L-Alanine, featuring deuterium, carbon-13, and nitrogen-15 isotopes. As a non-essential amino acid, L-Alanine plays a crucial role in glucose metabolism, enhances immune function, and serves as an energy source for muscle tissue, the brain, and the central nervous system. This reagent is particularly valuable in metabolic research, protein labeling, and isotopic tracing studies. -
Stable Isotope
3-Methyl-2-oxobutanoic acid-13C4,d4 sodium is a stable isotope-labeled compound that serves as a valuable tracer in metabolic studies. This compound can be utilized in various applications involving carbon and deuterium tracing, aiding in the understanding of metabolic pathways and kinetics. It is particularly useful in research related to metabolism, biochemistry, and isotopic labeling techniques. -
Stable Isotope
Pyrazine-d4 is a deuterated derivative of pyrazine, serving as a stable isotope. This compound is utilized in various applications including quantitative analysis, environmental studies, and metabolic research. Its unique isotopic labeling allows for enhanced detection and tracking of pyrazine in complex biological systems, making it a valuable tool for scientists investigating pyrazine-related pathways and interactions. -
Stable Isotope
Sodium 3-methyl-2-oxobutanoate-13C,d4 is a stable isotope-labeled form of Sodium 3-methyl-2-oxobutanoate, featuring deuterium and 13C modifications. This compound serves as an important precursor of pantothenic acid in Escherichia coli. It is primarily utilized in metabolic studies and tracer experiments to track and quantify metabolic pathways involving pantothenic acid biosynthesis. -
Stable Isotope
D-Mannose-13C-5 is a stable isotope-labeled form of D-Mannose, a monosaccharide integral to human metabolism and cellular glycosylation processes. This compound is used in research applications involving metabolic studies, carbohydrate metabolism, and glycoprotein synthesis. It serves as a valuable tool for isotopic tracing in biochemical assays and metabolic pathway analysis. -
Stable Isotope
N-Acetyl-D-glucosamine-13C-3 is a stable isotope-labeled derivative of N-Acetyl-D-glucosamine, a monosaccharide and fundamental component of glycoproteins and glycolipids. As a key building block in cellular processes, it plays a critical role in the biosynthesis of chitin and glycosaminoglycans. This reagent is primarily utilized in metabolic studies, isotopic tracing experiments, and research involving carbohydrate metabolism and signaling pathways. -
Stable Isotope
Sphinganine 1-phosphate-d7 is a deuterium-labeled form of Sphinganine 1-phosphate, a polar sphingolipid metabolite that plays a critical role in cellular processes. This compound is known to regulate cell migration, differentiation, and survival, making it essential for understanding complex physiological responses. It is particularly useful in research applications involving sphingolipid biology and in tracking metabolic pathways in studies of cell signaling and disease mechanisms. -
Stable Isotope
5-Hydroxymethyluracil-d3 is a deuterium-labeled form of 5-Hydroxymethyluracil, a molecule that arises from oxidative DNA damage. This compound serves as a potential epigenetic marker, influencing transcriptional activity through interaction with bacterial RNA polymerase. It is valuable for studies focusing on DNA damage repair mechanisms, epigenetics, and transcription regulation in various biological systems. -
Stable Isotope
2'-Deoxyguanosine-d2 monohydrate is a stable isotope-labeled analog of 2'-Deoxyguanosine. This compound serves as a valuable tool in metabolic studies, allowing for precise tracking of nucleic acid metabolism and dynamics in biological systems. Its applications extend to various fields, such as pharmacokinetics, biochemical assays, and isotopic labeling in molecular biology research. -
Stable Isotope
4-Methoxybenzaldehyde-d3 is the deuterated form of 4-Methoxybenzaldehyde, a naturally occurring aromatic phenolic compound known for its pleasant fragrance. This compound is found in various plant species, such as horseradish and anise, and is significant in studies investigating neurotoxic effects, including mortality and behavioral alterations in host-seeking. 4-Methoxybenzaldehyde-d3 serves as a valuable stable isotope labeled reagent for research applications in metabolism, pharmacokinetics, and environmental studies. -
Stable Isotope
Hydroxy Bosentan-d6 is a deuterated stable isotope of Hydroxy bosentan, a primary metabolite of Bosentan (BOS), which is processed by the cytochrome P450 enzyme system in the liver. This compound retains 10%-20% of the pharmacological activity of BOS, making it useful for studying BOS metabolism and effects. It serves as an essential tool in pharmacokinetic studies and drug metabolism research, facilitating a deeper understanding of bosentan's therapeutic profile. -
Stable Isotope
Stearic acid-d is the deuterated form of stearic acid, a long-chain saturated fatty acid commonly found in both animal and vegetable fats. As a stable isotope, it serves as a valuable tracer in metabolic and biochemical research. Stearic acid-d is utilized to study fatty acid metabolism, lipid synthesis, and cellular signaling pathways involving fatty acids. -
Stable Isotope
Suberylglycine-d4 is a deuterated form of Suberylglycine, an acyl glycine that serves as a minor metabolite of fatty acids. The stable isotope labeling in this compound allows for enhanced tracking and analysis in metabolic studies. Suberylglycine-d4 is useful in research applications involving metabolic flux analysis, lipid metabolism, and the study of fatty acid derivatives. -
Stable Isotope
Hexacosanoic acid-d4 is a deuterated form of hexacosanoic acid, a very long-chain fatty acid. This stable isotope is instrumental in metabolic studies and tracer experiments, allowing for the investigation of lipid metabolism and its implications in various diseases. Elevated levels of hexacosanoic acid have been linked to conditions such as X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia, making it valuable for research in neurological and metabolic disorders. -
Stable Isotope
N-Palmitoyl-D-sphingomyelin-d31 is a deuterium-labeled form of N-Palmitoyl-D-sphingomyelin, serving as a stable isotope. This compound is crucial for investigating sphingolipid metabolism and dynamics in cellular systems. Its incorporation in studies enables precise quantification and tracking of lipid behavior, which is essential for research in areas such as cell signaling and membrane biology. -
Stable Isotope
o-Toluic acid-13C is a stable isotope-labeled form of o-Toluic acid (2-Methylbenzoic acid), which is a benzoic acid derivative with a methyl group at the ortho position. This compound serves as a valuable tracers in metabolic studies, allowing for the investigation of xenobiotic metabolism and pathways in biological systems. Its use in research aids in understanding the mechanisms of drug metabolism and environmental toxicology. -
Stable Isotope
Estriol-d3-1 is a deuterium-labeled analog of Estriol. This stable isotope is utilized primarily in pharmacokinetic studies and metabolic research to trace and quantify Estriol in biological systems. Its unique labeling enhances detection sensitivity in mass spectrometry and other analytical techniques, facilitating investigations into hormone metabolism and dynamics. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-d9 is a deuterated form of Propane-1,2,3-triyl tripalmitate, functioning as a stable isotope. This compound acts as an endogenous metabolite and is commonly utilized in metabolic studies and tracer applications. Its deuterium labeling allows for enhanced detection and quantification in various biological systems, making it valuable in lipid metabolism research and mass spectrometry analysis. -
Stable Isotope
3,3-Dimethylacrylic acid-d6 is a stable isotope-labeled derivative of 3,3-Dimethylacrylic acid. This compound serves as an endogenous metabolite and is utilized in metabolic studies and tracer experiments. Its deuterium labeling enhances detection and quantification in mass spectrometry, facilitating investigations into metabolic pathways and mechanisms of various biological processes. -
Stable Isotope
Tripalmitin (Glycerol CC, 13C 99%) is a stable isotope-labeled glycerol triester of palmitic acid, specifically designed for metabolic studies. As an endogenous metabolite, it serves as a valuable tracer in lipid metabolism research, facilitating the investigation of fatty acid synthesis and breakdown pathways. This reagent is suitable for applications in both in vitro and in vivo studies, enabling precise quantification of lipid dynamics in biological systems. -
Stable Isotope
Lignoceric acid-d4 is a deuterium-labeled derivative of lignoceric acid, a 24-carbon saturated fatty acid (24:0) primarily synthesized in the developing brain. This stable isotope is valuable for tracking metabolic processes and analyzing fatty acid composition in biological systems. Research applications include studies related to Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy, enabling insights into these rare genetic disorders and their impact on lipid metabolism. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-d5 is a deuterium-labeled derivative of Propane-1,2,3-triyl tripalmitate, serving as a stable isotope. This compound is recognized as an endogenous metabolite, facilitating accurate metabolic studies and tracing experiments. It is commonly employed in research applications related to lipid metabolism and isotopic labeling in biological systems, enhancing the understanding of metabolic pathways and cellular functions. -
Stable Isotope
N-Acetylglycine-13C2,15N is a stable isotope-labeled derivative of N-Acetylglycine, incorporating both 13C and 15N isotopes. This compound serves as a valuable tool in metabolic studies and tracer experiments, allowing researchers to investigate the metabolic pathways and biological functions of N-Acetylglycine in various organisms. Its application as a flavor enhancer provides insights into sensory perception and food science, making it relevant for studies in nutrition and food chemistry. -
Stable Isotope
5-Methyluridine-3′-13C is a stable isotope-labeled derivative of 5-Methyluridine, an endogenous methylated nucleoside prevalent in human influenza. This compound is utilized in metabolic studies and isotopic tracing experiments to investigate nucleoside metabolism and RNA synthesis pathways. Its incorporation in research can enhance the understanding of viral replication and pathogenesis in infectious diseases. -
Stable Isotope
Heptyl methyl ketone-d5 is a stable isotope-labeled form of Heptyl methyl ketone, featuring five deuterium atoms. This compound is primarily utilized in isotope labeling studies and analytical applications, including mass spectrometry. It serves as a valuable tool for tracing molecular interactions and understanding metabolic processes in various biological research contexts. -
Stable Isotope
7-Methylguanine-d3 is a deuterium-labeled analog of 7-Methylguanine, a significant metabolite involved in DNA methylation processes. This stable isotope serves as a valuable probe for studying protein-DNA interactions and is crucial for enhancing the accuracy of DNA sequencing methodologies. Researchers utilize 7-Methylguanine-d3 to better understand epigenetic modifications and their implications in various biological contexts. -
Stable Isotope
D-Ribose-d is the deuterated form of D-Ribose, primarily utilized as a stable isotope for metabolic research. As a crucial component of adenosine triphosphate (ATP), D-Ribose is known to enhance energy production and is commonly employed in therapeutic approaches for chronic fatigue syndrome and cardiac energy metabolism disorders. Its biological activity extends to influencing protein glycosylation pathways, making it valuable in various biochemical studies. -
Stable Isotope
DL-Mevalonolactone-d3 is a deuterium-labeled derivative of DL-Mevalonolactone, a key intermediary in the mevalonate pathway. This compound has been shown to decrease mitochondrial membrane potential (Ψm), reduce NAD(P)H levels, and impair calcium retention in neural tissues, leading to mitochondrial swelling. It serves as a valuable tool in biochemical research aimed at investigating mitochondrial dysfunction and metabolic pathways. -
Stable Isotope
4-Methylcatechol-d3 is a deuterium-labeled variant of 4-Methylcatechol, a key metabolite of p-toluate. This compound serves as both a substrate and a suicide inhibitor for Catechol 2,3-Dioxygenase, facilitating studies on catechol metabolism and enzyme kinetics. It is valuable for research applications in metabolic pathway analysis and the development of enzyme inhibitors. -
Stable Isotope
Estradiol-13C2 is a stable isotope-labeled form of Estradiol, a crucial steroid sex hormone involved in regulating fertility and developing secondary sexual characteristics in females. It modulates biological activity by upregulating IL-6 expression through the estrogen receptor β (ERβ) signaling pathway. This compound is widely used in research applications investigating hormone signaling, reproductive biology, and related metabolic processes. -
Stable Isotope
D-Galactose-d-3 is a stable isotope-labeled form of D-Galactose, an aldohexose sugar that serves as the C-4 epimer of glucose. This reagent is essential for metabolic studies, particularly in tracing carbohydrate metabolism and analyzing galactose utilization pathways. Its deuterium labeling allows for enhanced sensitivity and specificity in mass spectrometry applications, making it a valuable tool for researchers investigating carbohydrate biochemistry and related metabolic disorders. -
Stable Isotope
L-Isoleucine-d is the deuterium-labeled form of the essential amino acid L-Isoleucine, characterized by its nonpolar hydrophobic properties. This stable isotope is utilized in metabolic studies, protein labeling, and isotope tracing experiments, making it valuable for research in fields such as biochemistry and molecular biology. Its unique labeling facilitates the investigation of metabolic pathways and enzyme kinetics in various biological systems. -
Stable Isotope
Boc-L-Ala-OH-3-13C is a stable isotope-labeled version of Boc-L-Ala-OH, specifically incorporating the 13C isotope. This compound exhibits a strong affinity for ATP, making it a valuable tool in studying ATP-dependent biological processes. Its structure features an amino acid moiety and an acylamide bond, which is characteristic of peptides and proteins, facilitating research in areas like protein synthesis and metabolic pathways.
