Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Octanoic acid-13C4 is a stable isotope-labeled form of octanoic acid, also known as caprylic acid. This compound serves as a valuable internal standard in mass spectrometry applications, facilitating the quantification of fatty acids in biological samples. Its unique isotopic signature allows for precise tracking of metabolic processes, making it an essential tool in lipid metabolism studies and related biochemical research. -
Stable Isotope
L-Serine-1-13C is a stable isotope-labeled form of the non-essential amino acid L-Serine. It plays a crucial role in cellular metabolism and proliferation, making it an important compound in various biological research applications. This isotope is particularly valuable in studies involving metabolic tracing and quantitative analysis of amino acid metabolism. -
Stable Isotope
L-Ornithine-d6 hydrochloride is a deuterium-labeled form of L-Ornithine, an essential free amino acid involved in the urea cycle. It plays a critical role in nitrogen metabolism and is utilized in various biochemical research applications, including metabolic studies and isotopic tracing. This stable isotope enhances the sensitivity and accuracy of analytical techniques in research focusing on amino acid metabolism and related pathways. -
Stable Isotope
Glutaric acid-d4 is a stable isotope of glutaric acid, a dicarboxylic acid involved in the metabolic pathways of lysine and tryptophan. Its biological activity includes modulation of pericyte contractility and migration, contributing to investigations in cellular dynamics. Glutaric acid-d4 serves as a valuable tool in research focusing on metabolic disorders, particularly as an indicator of glutaric aciduria type I. -
Stable Isotope
Triolein-13C3 is a stable isotope-labeled form of triolein, a symmetrical triacylglycerol. It is known to reduce the upregulation of MMP-1 and exhibits significant antioxidant and anti-inflammatory properties. This compound is valuable for research applications in metabolic studies and lipid metabolism, providing insights into the effects of dietary triglycerides on cellular processes. -
Stable Isotope
Creatinine-13C is a stable isotope-labeled form of creatinine, a breakdown product of creatine phosphate in muscle tissue. This compound is typically produced at a consistent rate in the human body, making it valuable for research applications in metabolic studies and kidney function assessment. Its use in isotopic labeling enhances the precision of analytical techniques, allowing for improved tracking of metabolic processes in various biological systems. -
Stable Isotope
β-Alanine-d4 is a stable isotope-labeled form of β-Alanine, a non-essential amino acid involved in the synthesis of carnosine. Carnosine acts as an important intracellular buffer, contributing to pH homeostasis in muscle cells. This reagent is valuable for metabolic studies, particularly in researching amino acid metabolism and carnosine's role in physiological processes. -
Stable Isotope
L-Serine-15N is a stable isotope-labeled form of L-Serine. As a non-essential amino acid, L-Serine is crucial in various biological processes, including cellular proliferation and metabolism. This isotopically labeled version is valuable for research applications in metabolic studies, tracer experiments, and protein labeling in proteomics. -
Stable Isotope
Linoleic acid-d4 is a deuterium-labeled derivative of linoleic acid, a polyunsaturated fatty acid commonly found in plant oils, nuts, and seeds. It serves as a crucial component of membrane phospholipids, contributing to the maintenance of membrane fluidity essential for the integrity of the transdermal water barrier in the epidermis. In research applications, linoleic acid-d4 can be used to investigate oxidative stress mechanisms, particularly its effects on red blood cells and hemoglobin. This stable isotope is valuable for studies involving metabolic pathways and lipid dynamics. -
Stable Isotope
L-Tryptophan-1-13C is a stable isotope-labeled form of the essential amino acid L-Tryptophan. It serves as a precursor for key biomolecules, including serotonin, melatonin, and vitamin B3, making it valuable in metabolic studies. This compound is useful in research applications such as probing metabolic pathways, isotopic labeling, and tracing the biosynthesis of neurotransmitters and hormones. -
Stable Isotope
DPPC-d62 is a deuterium-labeled derivative of dipalmitoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This stable isotope is instrumental in the preparation of liposomal monolayers, serving as a delivery vehicle in immunological studies. Research applications include the induction of immune responses against glycosphingolipid (GSL) antigens in murine models, facilitating enhanced understanding of lipid-mediated immune mechanisms. -
Stable Isotope
4β-Hydroxycholesterol-d4 is a deuterium-labeled derivative of 4β-Hydroxycholesterol, a significant metabolite of cholesterol. This compound serves as a precursor in bile acid synthesis and is present in human circulation. It is primarily utilized in research applications involving lipid metabolism, cholesterol homeostasis, and the assessment of cholesterol-derived signaling pathways. This stable isotope enables accurate quantitative analysis in mass spectrometry studies. -
Stable Isotope
Triolein-d5 is a deuterium-labeled form of triolein, a symmetrical triacylglycerol. This compound exhibits significant antioxidant and anti-inflammatory properties, while also being noted for its ability to reduce the upregulation of matrix metalloproteinase-1 (MMP-1). Triolein-d5 is primarily used as a stable isotope in metabolic studies and tracers in lipid metabolism research. -
Stable Isotope
Azelaic acid-d14 is a stable isotope-labeled derivative of azelaic acid, an organic compound derived from the ozonolysis of oleic acid. This reagent serves as a valuable tool for metabolic studies and tracer experiments, allowing for precise quantification and tracking of azelaic acid's biological processes in research. Azelaic acid has demonstrated antimicrobial properties and is commonly utilized in dermatological applications, making this labeled form highly relevant for pharmacokinetic and pharmacodynamic investigations. -
Stable Isotope
Deoxycorticosterone-d8 is a deuterated form of deoxycorticosterone, a steroid hormone that serves as a mineralocorticoid and precursor to aldosterone. This stable isotope is primarily used in research applications requiring precise quantification of steroid hormones in biological samples. Its incorporation of deuterium facilitates studies in metabolic pathways, hormone profiling, and pharmacokinetics of steroid-related compounds. -
Stable Isotope
3-Methoxy-4-hydroxyphenylglycol-d3 is a stable isotope-labeled derivative of 3-Methoxy-4-hydroxyphenylglycol, specifically incorporating deuterium atoms. This compound serves as a valuable internal standard in quantitative mass spectrometry and biochemical assays, facilitating the accurate measurement of biological samples. It is widely utilized in pharmacokinetic studies and metabolic research to track and analyze various metabolic pathways involving phenolic compounds. -
Stable Isotope
D-(+)-Trehalose-d14 is a deuterium-labeled derivative of D-(+)-Trehalose, serving as a stable isotope for research applications. Isolated from Saccharomyces cerevisiae, D-(+)-Trehalose plays a significant role as a protective sugar against cellular stress and is utilized in various biochemical studies. This compound is valuable for tracing metabolic pathways, enhancing understanding of cellular processes, and can be applied in formulations for food and pharmaceutical research. -
Stable Isotope
Arachidic acid-d39 is a deuterium-labeled derivative of arachidic acid, a long-chain saturated fatty acid. This stable isotope is utilized in metabolic studies and tracer experiments to investigate lipid metabolism and the dynamics of fatty acid incorporation in biological systems. Arachidic acid has been identified in human plasma phospholipids and various plant oils, and it interacts with chitosan oligosaccharides for potential applications in targeted anti-cancer drug delivery research. -
Stable Isotope
25-Hydroxycholesterol-d6 is a deuterium-labeled form of 25-Hydroxycholesterol, a metabolite of cholesterol synthesized and released by macrophages upon Toll-like receptor (TLR) activation. This compound serves as a selective and potent inhibitor of immunoglobulin A (IgA) production in B cells, with an effective concentration (EC50) of approximately 65 nM. Its unique labeling makes it a valuable tool for tracing cholesterol metabolism and studying immune response mechanisms in various research applications. -
Stable Isotope
Calcifediol-d3 is a deuterium-labeled form of Calcifediol, serving as an effective ligand for the Vitamin D Receptor (VDR) and a viable Vitamin D supplement. As a prohormone within the vitamin D endocrine system (VDES), it undergoes hepatic hydroxylation to form calcitriol, the bioactive variant of vitamin D. Calcifediol-d3 can effectively elevate serum vitamin D levels, making it useful in research focused on vitamin D metabolism and VDR signaling pathways. -
Stable Isotope
Vanillylmandelic acid-d3 is a deuterium-labeled derivative of vanillylmandelic acid, which serves as a stable isotope in research applications. As the final metabolite of epinephrine and norepinephrine, it serves as a biomarker for assessing disorders in neurotransmitter metabolism. Additionally, vanillylmandelic acid exhibits antioxidant properties, displaying activity against the DPPH radical with an IC50 value of 33 μM, making it useful in studies of oxidative stress and related pathways. -
Stable Isotope
Normetanephrine-d3 hydrochloride is a stable isotope-labeled form of Normetanephrine hydrochloride, which serves as the O-methylated metabolite of norepinephrine (NE). This compound is utilized in various research applications, particularly in metabolic studies and pharmacokinetics, providing insights into phenolic compound metabolism. Its deuterium labeling enhances the sensitivity and accuracy of analytical techniques, making it a valuable tool for scientists studying catecholamine pathways and their physiological implications. -
Stable Isotope
D-Glucose-d2 is a deuterium-labeled form of D-Glucose, a key monosaccharide involved in various metabolic processes. This stable isotope is essential for metabolic research and can be used to trace metabolic pathways, providing insights into cellular energy metabolism and signaling mechanisms in response to environmental stresses. Its incorporation into biological systems allows for precise analysis of glucose utilization and metabolism in different conditions. -
Stable Isotope
L-Tyrosine-d5 is a deuterated form of the non-essential amino acid L-Tyrosine, used as a stable isotope in metabolic studies. This reagent is utilized to trace metabolic pathways and analyze amino acid metabolism in various biological systems. Its application extends to research in neurobiology, as it can influence the activity of enzymes such as citrate synthase in the central nervous system. -
Stable Isotope
Paraxanthine-d6 is a deuterium-labeled derivative of Paraxanthine, a significant caffeine metabolite. This stable isotope can be utilized in metabolic studies and tracer experiments to investigate the pharmacokinetics of caffeine and its metabolites. Paraxanthine has been shown to offer neuroprotective effects against dopaminergic cell death through the modulation of Ryanodine Receptor Channels, highlighting its relevance in neurobiology and toxicology research. -
Stable Isotope
NNK-d4 is a deuterium-labeled analog of NNK, a potent tobacco-specific nitrosamine. This stable isotope is utilized in pharmacokinetic studies to trace the metabolism and distribution of NNK in biological systems. Research applications include understanding the mechanisms of carcinogenesis and evaluating the effects of tobacco-related compounds on cellular processes. -
Stable Isotope
Spermidine-13C4 hydrochloride is a stable isotope-labeled derivative of spermidine, targeting cellular processes related to membrane stability and antioxidant activity. This compound enhances the activity of antioxidant enzymes, supports the integrity of photosystem II (PSII), and modulates relevant gene expression. Additionally, it effectively reduces hydrogen peroxide (H2O2) and superoxide (O2.-) levels, making it a valuable tool for research in cellular biology and oxidative stress studies. -
Stable Isotope
C18-Ceramide-d7 is a deuterium-labeled variant of C18-Ceramide, designed as a stable isotope applicable in metabolic studies. This compound serves as a valuable tool for tracing lipid metabolism and studying the role of ceramides in various biological processes. Its use in mass spectrometry enables precise quantification and evaluation of ceramide-related pathways in research applications. -
Stable Isotope
D-Fructose-13C is a stable isotope-labeled form of D-Fructose, an important naturally occurring monosaccharide found in various plants. This compound is primarily utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and energy production pathways. Its stable isotope labeling allows for precise tracking in both in vitro and in vivo studies, making it a valuable tool in biochemical and nutritional research applications. -
Stable Isotope
L-Citrulline-13C is a stable isotope-labeled form of L-Citrulline, an amino acid produced from the catabolism of proline, glutamine, and glutamate, or synthesized from L-arginine through the arginine-citrulline pathway. This compound is utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and nitric oxide synthesis. Its incorporation into various biological systems allows for precise tracking of metabolic pathways and enhances the understanding of cellular functions related to cardiovascular health and exercise physiology. -
Stable Isotope
L-Methionine-13C5,15N is a stable isotope-labeled form of the essential amino acid, L-Methionine, featuring five carbon-13 and one nitrogen-15 isotopes. This compound plays a vital role in various biological processes, including protein synthesis and as a hepatoprotectant. L-Methionine-13C5,15N is commonly utilized in metabolic studies, tracer studies, and nutritional research to elucidate amino acid metabolism and the dynamics of protein turnover. -
Stable Isotope
DL-Glutamic acid-d3 is the deuterium-labeled derivative of DL-Glutamic acid, a crucial metabolite in various biological processes. This stable isotope serves as a valuable tracer in metabolic studies, allowing for precise tracking and quantification of metabolic pathways. DL-Glutamic acid's stability, compared to its L-isomer polymorphs, enhances its utility in experimental research involving amino acid metabolism and related biochemical pathways. -
Stable Isotope
Stearic acid-d5 is a deuterium-labeled derivative of stearic acid, a long-chain saturated fatty acid prevalent in various animal and vegetable fats. As a stable isotope, stearic acid-d5 serves as an important tool in metabolic studies and tracer experiments, enabling researchers to accurately track the metabolism of fatty acids in biological systems. Its applications extend to lipid metabolism research, providing insights into fatty acid synthesis and degradation pathways. -
Stable Isotope
Methylmalonic acid-d3 is a stable isotope-labeled form of Methylmalonic acid that serves as an important biomarker for assessing Vitamin B-12 deficiency, particularly in cancer research. Its deuterium labeling provides enhanced sensitivity in analytical techniques such as mass spectrometry. This compound is essential for studies investigating the metabolic pathways associated with vitamin deficiencies and their implications in oncology. -
Stable Isotope
Cholestenone-d5 is a deuterium-labeled analog of Cholestenone, a key metabolite that serves as an intermediate in cholesterol oxidation, predominantly occurring in the liver. This compound plays a significant role in membrane dynamics, influencing cholesterol translocation and efflux processes. Cholestenone-d5 is ideal for studies exploring cholesterol metabolism and its potential long-term effects on cellular function. -
Stable Isotope
Estrone-d4 is a deuterated form of estrone, a naturally occurring estrogenic hormone. Estrone plays a crucial role in various biological processes as a principal endogenous estrogen, primarily synthesized in adipose tissue from androstenedione through aromatization. Estrone-d4 serves as a stable isotope internal standard in quantifying estrone and related estrogens in biological samples, facilitating research in hormone metabolism, endocrine function, and related health studies. -
Stable Isotope
L-Tyrosine-d2-1 is the deuterium-labeled form of L-Tyrosine, a non-essential amino acid. This compound primarily functions as a stable isotope tracer in metabolic studies. It is utilized in research to investigate amino acid metabolism and neuronal signaling, particularly in relation to the modulation of citrate synthase activity in the posterior cortex. -
Stable Isotope
L-Methionine-15N is a stable isotope-labeled form of L-Methionine, the L-isomer of the essential amino acid Methionine. This compound plays a critical role in human development and serves as a hepatoprotectant, helping to safeguard liver function. L-Methionine-15N is valuable for metabolic research, specifically in studies involving amino acid metabolism and tracer applications in vivo. -
Stable Isotope
Desmosterol-d6 is a deuterium-labeled derivative of desmosterol. As a stable isotope, it serves as a valuable tool in tracing and studying cholesterol biosynthesis, specifically in the Bloch pathway where it acts as the immediate precursor to cholesterol. This compound is utilized in metabolic studies to provide insights into cholesterol metabolism and its regulatory mechanisms in various biological systems. -
Stable Isotope
Palmitoleic acid-d13 is a deuterium-labeled derivative of palmitoleic acid, which serves as a stable isotope in biological research. Palmitoleic acid is a monounsaturated fatty acid that has been shown to play a role in preventing cerebrovascular disorders, particularly in hypertensive rat models. This reagent is useful in studies investigating lipid metabolism, cellular signaling, and the physiological effects of fatty acids in various biological contexts. -
Stable Isotope
Aminoadipic acid-d3 is a deuterated form of aminoadipic acid, serving as a stable isotope for metabolic studies. It plays a critical role as an intermediate in lysine metabolism and the biosynthesis of saccharopine. This reagent is valuable in tracer studies, allowing researchers to investigate metabolic pathways and quantify metabolic flux in various biological systems. -
Stable Isotope
Choline-d13 chloride is a stable isotope-labeled form of choline chloride, an organic compound and quaternary ammonium salt. As a substrate for choline acetyltransferase, it plays a crucial role in acetylcholine synthesis. This reagent is valuable for research applications involving metabolic studies, tracer experiments in biological systems, and the investigation of choline's role in growth and development. -
Stable Isotope
2'-Deoxyguanosine-13C10 is a stable isotope-labeled derivative of 2'-Deoxyguanosine, specifically enriched with ten carbon-13 isotopes. This compound serves as a valuable internal standard for quantitative mass spectrometry and NMR studies, aiding in the investigation of nucleoside metabolism and biochemical pathways involving deoxyribonucleic acid (DNA) synthesis. Its application in tracer studies provides insights into cellular processes and molecular interactions in various biological systems. -
Stable Isotope
Hydrocinnamic acid-d9 is the deuterated form of hydrocinnamic acid, acting primarily as a stable isotope. This compound facilitates the study of hydrocinnamic acid's growth regulatory activities in rhizospheric environments, allowing for enhanced tracking and analysis in metabolic and plant growth research. Its unique isotopic labeling enables accurate quantification and tracing in various biological assays. -
Stable Isotope
5-Aminolevulinic acid-13C2,15N hydrochloride is a stable isotope-labeled form of 5-Aminolevulinic acid (5-ALA) featuring isotopes of carbon and nitrogen. This compound is primarily utilized in metabolic studies and tracer experiments to investigate biological processes involving heme biosynthesis. Its unique isotopic labeling makes it valuable for enhancing the precision of metabolic flux analysis and other research applications in biochemistry and molecular biology. -
Stable Isotope
Creatine-d3 hydrate is a stable isotope labeled form of creatine hydrate that serves as a vital component in energy metabolism in muscle and brain cells. This deuterium-labeled compound is essential for tracer studies, allowing researchers to investigate metabolic pathways and energy dynamics under various physiological and pathological conditions. Its application extends to studying muscle physiology and neuroenergetics, contributing significantly to the understanding of metabolic disorders. -
Stable Isotope
L-Proline-15N is a stable isotope-labeled form of the amino acid L-Proline, integrating a nitrogen-15 isotope. This compound serves as a crucial building block in protein synthesis and is widely utilized in metabolic studies and protein characterization. L-Proline-15N enables researchers to investigate amino acid metabolism and protein interactions using isotope labeling techniques, enhancing insights into biological processes. -
Stable Isotope
L-Methionine-34S is a stable isotope-labeled form of L-Methionine, specifically incorporating the sulfur-34 isotope. As an essential amino acid, L-Methionine plays a critical role in various biological processes, including protein synthesis and metabolic regulation. This compound is utilized in isotopic labeling studies, helping to trace metabolic pathways and investigate amino acid metabolism in both cellular and whole organism models. Its hepatoprotective properties further underscore its importance in research related to liver function and detoxification processes. -
Stable Isotope
3-Indoleacetic acid-2,2-d2 is a stable isotope-labeled derivative of 3-Indoleacetic acid, a key auxin that functions as a natural plant growth hormone. This compound is utilized to investigate plant cell elongation and division in various research applications. Its deuterium labeling allows for enhanced tracking and analysis in metabolic studies and experiments involving hormone signaling pathways. -
Stable Isotope
C16-Ceramide-d9 is a deuterium-labeled analogue of C16-Ceramide, serving as a stable isotope for biochemical studies. This compound is essential for investigating sphingolipid metabolism and signaling pathways, including apoptosis and cell growth regulation. C16-Ceramide-d9 is utilized in mass spectrometry and tracer studies to enhance the understanding of lipid biology and cellular processes.
