Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Oxalic acid-13C2 is a stable isotope-labeled form of oxalic acid, a strong dicarboxylic acid found in various plants and vegetables. This reagent is primarily utilized in analytical chemistry applications and serves as a general reducing agent. Its isotopic labeling makes it particularly valuable for metabolic studies and tracer experiments, facilitating the investigation of biochemical pathways and compound interactions in research settings. -
Stable Isotope
D-Glucose-d7 is a deuterated form of D-Glucose, serving as a stable isotope for various biological applications. As a primary monosaccharide in cellular metabolism, D-Glucose plays a vital role in energy production and is involved in cellular signaling related to metabolic status and stress responses. This reagent is commonly used in isotopic labeling studies to investigate metabolic pathways, enabling enhanced analysis in biochemical research and metabolic tracing experiments. -
Stable Isotope
Cholic acid-d5 is a deuterium-labeled derivative of cholic acid, a key primary bile acid synthesized in the liver, often conjugated with glycine or taurine. It plays a critical role in the emulsification of fats, enhancing fat absorption and promoting cholesterol excretion. This stable isotope is particularly useful in metabolic studies, tracer experiments in lipid metabolism, and bile acid research. -
Stable Isotope
D-Phenylalanine-d5 is a deuterium-labeled form of D-Phenylalanine, the synthetic dextro isomer of phenylalanine. This stable isotope is utilized in studies assessing metabolic pathways and pharmacokinetics. Notably, D-Phenylalanine exhibits inhibitory effects on biofilm formation in Pseudoalteromonas sp. SC2014, making it significant for research in biofilm-associated infections and antimicrobial strategies. -
Stable Isotope
Octanoic acid-d15 is the deuterium-labeled form of octanoic acid, also known as caprylic acid. This stable isotope is utilized in various research applications, including metabolic studies and tracer experiments, allowing for precise tracking of fatty acid metabolism. Octanoic acid itself is recognized for its role in ester production, particularly in perfumery and dye manufacturing. -
Stable Isotope
L-Tyrosine-13C6 is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine. This compound can modulate metabolic pathways by inhibiting citrate synthase activity, particularly in the posterior cortex. L-Tyrosine-13C6 is utilized in research applications focusing on metabolic studies, amino acid metabolism, and neurobiological research. -
Stable Isotope
L-Tyrosine-13C9 is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine, featuring nine carbon-13 atoms. This compound is utilized in metabolic studies to trace the biosynthesis of proteins and other biomolecules. Key applications include investigating metabolic pathways and assessing the inhibition of citrate synthase activity, particularly in the posterior cortex, to understand its role in neurobiology and related fields. -
Stable Isotope
L-5-Hydroxytryptophan-d3 is a deuterium-labeled derivative of L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid that serves as a precursor to the neurotransmitter serotonin. Its primary biological activity includes modulation of serotonin levels, making it useful in investigations related to mood disorders, appetite control, and sleep regulation. L-5-Hydroxytryptophan-d3 is employed in various research applications, including studies on fibromyalgia, migraine management, and myoclonus, where precise tracing of biochemical pathways is essential. -
Stable Isotope
Spermidine-d6 is a deuterium-labeled analog of spermidine, a key polyamine involved in cellular functions. It has been shown to enhance cell membrane stability and elevate antioxidant enzyme activities, thus promoting the efficiency of photosystem II (PSII). Additionally, spermidine-d6 significantly reduces hydrogen peroxide and superoxide levels, making it valuable for research related to oxidative stress and cellular resilience. -
Stable Isotope
N-Acetyl-L-aspartic acid-d3 is a stable isotope-labeled form of N-Acetyl-L-aspartic acid, which serves as an acetyl donor and is an important derivative of aspartic acid. This compound plays a crucial role in brain metabolism and is utilized in research focused on neurodegenerative diseases, including Canavan disease. Its stable isotope labeling aids in metabolic studies and tracking biochemical pathways involving N-Acetyl-L-aspartic acid in neurological contexts. -
Stable Isotope
Hypoxanthine-15N4 is a stable isotope-labeled form of hypoxanthine, a purine derivative. This compound serves as a potential free radical generator and can be utilized as a biomarker for hypoxia in various biological studies. Its unique labeling allows for precise tracking and analysis in metabolic research and cellular assays. -
Stable Isotope
Stearic acid-13C18 is a stable isotope-labeled form of stearic acid, a long-chain saturated fatty acid found in various animal and plant fats and oils. As a stable isotope, it serves as a valuable tracer in metabolic studies, enabling researchers to investigate fatty acid metabolism and biological pathways involving lipid synthesis and oxidation. This reagent is essential for applications in nutritional research, pharmacokinetics, and the study of lipid-related disorders. -
Stable Isotope
(S)-Malic acid-d3 is a deuterated form of (S)-malic acid, specifically designed for use in stable isotope labeling applications. This naturally occurring dicarboxylic acid is known for its contribution to the characteristic sour flavor of fruits and serves as an important food additive. In chemical research, (S)-malic acid-d3 can be employed in metabolic studies, tracer experiments, and the investigation of biochemical pathways involving malate metabolism. -
Stable Isotope
L-Tryptophan-d3 is a deuterium-labeled form of the essential amino acid L-Tryptophan. This compound serves as a precursor for the biosynthesis of important neurotransmitters such as serotonin and melatonin, as well as vitamin B3. L-Tryptophan-d3 is widely utilized in metabolic studies, isotope labeling experiments, and research focused on sleep regulation and mood disorders. Its stable isotope properties enable precise tracking of metabolic pathways in biological systems. -
Stable Isotope
Itaconic acid-13C5 is a stable isotope-labeled version of Itaconic acid, which serves as a critical building block for polymers, chemicals, and biofuels. This metabolite is predominantly associated with macrophages and plays a significant role in mediating interactions between macrophage metabolism and peritoneal tumors. Itaconic acid-13C5 can be utilized in metabolic studies, tracer experiments, and investigations focused on immune cell metabolism in cancer research. -
Stable Isotope
L-Tyrosine-d2 is a deuterium-labeled form of the non-essential amino acid L-Tyrosine. It serves as a stable isotope used in metabolic studies and tracer experiments. This compound is known to inhibit citrate synthase activity in the posterior cortex, making it valuable for research in neurobiology and metabolic regulation. -
Stable Isotope
L-Hydroxyproline-d3 is a deuterium-labeled derivative of L-Hydroxyproline, a key chiral building block in pharmaceutical synthesis. The stable isotope labeling facilitates quantification and tracing in metabolic studies. This compound is essential for research applications in biochemical pathways, protein structure analysis, and the development of therapeutic agents. -
Stable Isotope
D-Galactose-13C6 is a stable isotope-labeled form of D-Galactose, where carbon-13 isotopes are incorporated into the molecule. D-Galactose is a naturally occurring aldohexose and a C-4 epimer of glucose, widely utilized in metabolic studies. This reagent is valuable for tracing metabolic pathways and studying carbohydrate metabolism in various biological systems. -
Stable Isotope
4-Hydroxyphenylacetic acid-d6 is a deuterated form of 4-Hydroxyphenylacetic acid, serving as a stable isotope for research applications. This compound is a significant microbiota-derived metabolite of polyphenols and is involved in antioxidative mechanisms. It has been shown to induce the expression of the transcription factor Nrf2, making it useful for studies focused on oxidative stress and related signaling pathways. -
Stable Isotope
L-Leucine-15N is a stable isotope-labeled form of L-Leucine, an essential branched-chain amino acid that plays a critical role in protein synthesis and metabolic regulation. By activating the mTOR signaling pathway, L-Leucine-15N facilitates studies on cellular growth, metabolism, and muscle protein synthesis. This reagent is useful for research applications involving metabolic tracking, protein dynamics, and nutritional studies in various biological systems. -
Stable Isotope
Cholic acid-13C is a stable isotope-labeled form of cholic acid, a primary bile acid synthesized in the liver. This compound plays a significant role in lipid metabolism by enhancing fat absorption and promoting cholesterol excretion. Cholic acid-13C is valuable for tracing studies in metabolic research, allowing scientists to investigate bile acid dynamics and related metabolic pathways. -
Stable Isotope
Pyruvic acid-13C is a stable isotope-labeled form of pyruvic acid, which serves as a key intermediate in the metabolism of carbohydrates, proteins, and fats. This compound is widely utilized in metabolic studies and tracer studies to investigate metabolic pathways and energy production. Its incorporation into experimental designs supports research in nutrition, cellular respiration, and metabolic regulation. -
Stable Isotope
L-Carnitine-d9 is a deuterated form of L-Carnitine, an endogenous compound essential for fatty acid metabolism. It plays a crucial role in the transport of long-chain fatty acyl-CoAs into the mitochondria, facilitating their degradation through β-oxidation. This stable isotope is valuable for metabolic research and can aid in the investigation of metabolic disorders and inborn errors of metabolism where L-Carnitine’s role is significant. -
Stable Isotope
Malic acid-d3 is a deuterium-labeled derivative of malic acid (hydroxybutanedioic acid), a naturally occurring dicarboxylic acid found in various fruits, notably apples and pears. As a stable isotope, malic acid-d3 is utilized in isotopic labeling studies to trace metabolic pathways and investigate biochemical processes. This compound is valuable in numerous research applications, including metabolic flux analysis and the study of organic acid metabolism. -
Stable Isotope
L-Proline-13C5,15N is a stable isotope-labeled form of L-Proline, incorporating five carbon-13 and one nitrogen-15 isotopes. L-Proline is a non-essential amino acid that plays a crucial role in protein synthesis and cellular metabolism. This isotopic labeling allows for enhanced tracking and analysis in metabolic studies, enabling researchers to explore amino acid kinetics, protein synthesis, and metabolic pathways in various biological systems. -
Stable Isotope
Progesterone-d9 is a deuterium-labeled form of the steroid hormone progesterone, which plays a pivotal role in regulating the menstrual cycle and supporting pregnancy. As a stable isotope, Progesterone-d9 is instrumental in various analytical applications, including mass spectrometry and metabolic studies. Researchers utilize this reagent to trace metabolic pathways and assess hormone levels in biological samples, enhancing the understanding of reproductive health and endocrine functions. -
Stable Isotope
D-Mannose-13C6 is a stable isotope-labeled carbohydrate essential for metabolic studies. It plays a significant role in human metabolism, particularly in the glycosylation of proteins. This reagent is valuable for research applications involving metabolic flux analysis and tracing pathways in glycoprotein synthesis. -
Stable Isotope
L-Isoleucine-d10 is a stable isotope-labeled form of the essential nonpolar amino acid L-isoleucine, incorporating ten deuterium atoms. This compound is valuable in metabolic studies, tracer experiments, and protein labeling applications, allowing for enhanced tracking and quantification in biological systems. L-Isoleucine plays a crucial role in protein synthesis and energy production, making it significant for research in nutrition, cellular metabolism, and muscle physiology. -
Stable Isotope
Glycodeoxycholic acid-d4 is a deuterium-labeled derivative of Glycodeoxycholic Acid, an important endogenous metabolite. This stable isotope is utilized in various metabolic studies and tracer experiments, enhancing the understanding of bile acid dynamics and their roles in gastrointestinal physiology. Its applications extend to research pertaining to liver function, cholesterol metabolism, and disorders associated with bile acid dysregulation. -
Stable Isotope
Lignoceric acid-d4-1 is the deuterated form of lignoceric acid, a 24-carbon saturated fatty acid (Tetracosanoic acid) primarily synthesized in the developing brain. This stable isotope serves as a valuable tool in metabolic studies, particularly relating to Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. Its unique labeling enables researchers to track metabolic pathways and study lipid metabolism in various biological contexts. -
Stable Isotope
Estrone sulfate-d4 sodium is a deuterium-labeled derivative of Estrone sulfate, primarily utilized as a stable isotope in research. It serves as a precursor to bioactive estrogens, Estrone and Estradiol, through enzymatic conversion in various biological systems. This compound is important for studying estrogen metabolism and signaling pathways, particularly in breast cancer research, where it has been shown to promote the proliferation of mammary tumor cells and influence tumor growth in experimental models. Its role as a substrate for the OATP1B3 transporter also highlights its relevance in pharmacokinetic studies. -
Stable Isotope
Stearic acid-d3 is a stable isotope-labeled form of stearic acid, a long-chain saturated fatty acid commonly found in various animal and vegetable fats and oils. This compound is utilized in metabolic studies and lipid research to trace fatty acid metabolism and distribution in biological systems. Its deuterated form enables precise quantification and tracking in mass spectrometry applications, aiding in understanding fatty acid synthesis and metabolism pathways. -
Stable Isotope
Bisphenol A-d16 is the deuterated version of Bisphenol A, a key phenolic compound utilized in the synthesis of polycarbonate plastics and epoxy resins. This stable isotope is valuable for research applications related to environmental monitoring and toxicology, given Bisphenol A's classification as an endocrine-disrupting compound (EDC) and its associations with various health issues, including reproductive disorders and metabolic diseases. The use of Bisphenol A-d16 aids in tracking and quantifying the compound's presence and effects in biological systems. -
Stable Isotope
Pentadecanoic acid-d29 is a stable isotope-labeled form of pentadecanoic acid, a saturated fatty acid characterized by a 15-carbon backbone. This compound serves as a valuable tool in metabolic studies and tracer applications due to its unique isotopic signature. It is particularly useful in investigating fatty acid metabolism and lipid biochemistry in various biological systems. -
Stable Isotope
L-Tryptophan-15N2 is a stable isotope-labeled form of the essential amino acid L-Tryptophan. As a precursor to key biomolecules such as serotonin, melatonin, and vitamin B3, this compound is essential in studies related to neurotransmitter function and metabolic pathways. L-Tryptophan-15N2 is valuable in metabolic tracing experiments and isotopic labeling studies in various biological systems. -
Stable Isotope
Ethynyl Estradiol-d4 is a deuterium-labeled derivative of Ethynyl Estradiol, a synthetic estrogen primarily employed in oral contraceptive formulations. This compound serves as a stable isotope standard for mass spectrometry and other analytical techniques. Additionally, Ethynyl Estradiol-d4 contains an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC). Its applications extend to click chemistry, facilitating the study of biological processes and drug development. -
Stable Isotope
D-Glutamic acid-d5 is a deuterium-labeled analog of D-glutamic acid, serving as a stable isotope. This compound is typically employed in metabolic studies and tracer experiments to investigate D-glutamic acid's biological functions and pathways. Its applications extend to the pharmaceutical and food industries, where it can contribute to research in neurochemistry and sensory analysis. -
Stable Isotope
N-Methylnicotinamide-d4 is a deuterium-labeled derivative of N-Methylnicotinamide, serving as a stable isotope for metabolic studies. This compound is an endogenous metabolite known for its antithrombotic properties, acting primarily through the production and release of prostacyclin, which inhibits arterial thrombosis formation. Its role as the N-methylation product of nicotinamide, catalyzed by N-methyltransferase, positions it as a valuable tool in the analysis of nicotinate and nicotinamide metabolic pathways. -
Stable Isotope
Indolelactic acid-d5 is a stable isotope-labeled derivative of Indolelactic acid. This compound serves as a tryptophan catabolite and is particularly relevant in the study of metabolic pathways in Azotobacter vinelandii. It is utilized in various research applications, including tracing metabolic processes and investigating tryptophan degradation pathways. -
Stable Isotope
L-Leucine-d10 is a deuterium-labeled form of the essential branched-chain amino acid L-Leucine. It activates the mTOR signaling pathway, which is crucial for regulating cellular growth, metabolism, and protein synthesis. This stable isotope is particularly valuable in metabolic studies, allowing researchers to trace pathways and quantify amino acid metabolism in various biological systems. -
Stable Isotope
Succinic acid-d6 is a deuterium-labeled form of succinic acid, a key intermediate in the tricarboxylic acid cycle. This stable isotope is widely used in metabolic studies and tracer experiments, providing insights into metabolic pathways and cellular metabolism. It serves as a valuable tool in research applications involving metabolic flux analysis and isotopic labeling studies. -
Stable Isotope
Cholesterol-d6-1 is a deuterated form of cholesterol, a key sterol in mammalian biology. This stable isotope plays a critical role in cellular membranes, comprising 20-25% of their structural components, and influencing membrane fluidity and permeability characteristics. Additionally, cholesterol modulates the function of transporters and signaling proteins, and acts as an endogenous agonist for estrogen-related receptor α (ERRα). Cholesterol-d6-1 is valuable for studies in lipid metabolism, membrane dynamics, and receptor signaling pathways. -
Stable Isotope
Glycocyamine-d2 is a deuterium-labeled stable isotope of glycocyamine, a crucial precursor in creatine synthesis. This compound plays a significant role in energy metabolism regulation and promotes myogenic differentiation by activating the Akt/mTOR/S6K signaling pathway through the modulation of miR-133a-3p and miR-1a-3p. Glycocyamine-d2 enhances the expression of muscle-specific factors such as MyoD and MyoG, increases muscle creatine levels, and supports ATP homeostasis via the creatine phosphate/creatine kinase system. Its applications extend to research involving feed additives in poultry farming and muscle physiology studies. -
Stable Isotope
Urea-d4 is a deuterium-labeled isotope of urea, commonly utilized in stable isotope labeling studies. Urea serves as a potent protein denaturant through both direct and indirect pathways, and it also functions as an effective emollient and keratolytic agent. In research, it aids in the assessment of renal function by measuring blood urea nitrogen (BUN) levels. Additionally, urea's nitrogen content makes it a valuable compound in fertilizers and a key raw material in various chemical processes. -
Stable Isotope
Glycocyamine-15N,13C2 is a stable isotope-labeled form of Glycocyamine, featuring both 13C and 15N stable isotopes. As a direct precursor of creatine, it serves as an effective regulator of energy metabolism and a promoter of myogenic differentiation. Glycocyamine activates the Akt/mTOR/S6K signaling pathway through miR-133a-3p and miR-1a-3p, enhancing the expression of myogenic differentiation factors such as MyoD and MyoG. Its role in increasing muscle creatine concentration and maintaining ATP homeostasis makes it an important reagent for research applications, particularly in studies related to feed additives in poultry farming. -
Stable Isotope
Trimethylammonium chloride-d9 is a deuterium-labeled derivative of trimethylammonium chloride, a stable isotope that serves as a valuable internal standard in quantitative mass spectrometry. This compound is an endogenous metabolite involved in various biological processes and lipid metabolism. Its unique isotopic labeling enables sensitive tracking and quantification of metabolites in biological samples, facilitating research in metabolism and cellular biochemistry. -
Stable Isotope
3-Indoleacetic acid-13C6 is a stable isotope-labeled form of 3-Indoleacetic acid, a naturally occurring plant growth hormone classified as an auxin. This compound plays a crucial role in promoting cell elongation and division in plant tissues. Researchers utilize 3-Indoleacetic acid-13C6 in metabolic studies and isotopic tracing experiments to investigate auxin biosynthesis, transport, and signaling pathways in plant development. -
Stable Isotope
D-Alanine-d3 is a deuterium-labeled derivative of D-Alanine, primarily utilized as a stable isotope in biochemical research. This compound acts as a weak agonist for glycine receptors (GlyR), exhibiting an EC50 value of 9 mM. D-Alanine-d3 is valuable for studies investigating neurotransmission and receptor pharmacology, as well as in metabolic labeling applications. -
Stable Isotope
(R)-3-Hydroxybutanoic acid-13C4 sodium is a stable isotope-labeled variant of (R)-3-Hydroxybutanoic acid, which serves as a key metabolite derived from acetoacetic acid through the action of 3-hydroxybutyrate dehydrogenase. This compound plays a crucial role as an energy source and is involved in the biosynthesis of essential metabolites, including vitamins, antibiotics, and pheromones. It is valuable for metabolic studies, tracer experiments, and investigations into lipid metabolism and cellular energy pathways. -
Stable Isotope
Glycoursodeoxycholic acid-d4 is a stable isotope-labeled derivative of glycoursodeoxycholic acid, specifically deuterated at four positions. This compound acts as a bile acid-glycine conjugate, linked to metabolic pathways of ursodeoxycholic acid. It is commonly utilized in biochemical research to study bile acid metabolism and transport mechanisms, providing valuable insights into liver function and gastrointestinal physiology.
