Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Pyruvic acid-13C sodium is a stable isotope-labeled form of pyruvic acid, an important intermediate in the metabolic pathways of carbohydrates, proteins, and fats. This reagent is primarily utilized in metabolic research and tracer studies to investigate metabolic flux and pathway analysis. The incorporation of the 13C label allows for enhanced tracking and quantification in various analytical applications, helping to elucidate metabolic dynamics in biological systems. -
Stable Isotope
Taurocholic acid-d4 is a deuterium-labeled derivative of Taurocholic acid, which primarily functions as a bile acid. This compound plays a crucial role in the emulsification of dietary fats, thereby facilitating lipid digestion and absorption. Taurocholic acid-d4 is useful in research applications requiring stable isotopic labeling for metabolic studies, particularly in the investigation of bile acid metabolism and its effects on gastrointestinal physiology. -
Stable Isotope
Indole-13C is a stable isotope-labeled variant of indole, which serves as an important endogenous metabolite. This compound is primarily used in metabolic studies to trace biochemical pathways and analyze metabolic processes in various biological systems. Its stable isotope labeling facilitates precise quantitative analysis in research applications, including pharmacokinetics, drug metabolism, and biological profiling. -
Stable Isotope
5a-Pregnane-3,20-dione-d6 is a deuterated form of 5a-Pregnane-3,20-dione, an important endogenous metabolite of progesterone. This stable isotope is utilized in research applications involving metabolic studies, isotope labeling, and mass spectrometry. Its unique isotopic signature enables precise tracking and quantification of progesterone metabolism in biological systems. -
Stable Isotope
Pyridoxine-d3 hydrochloride is a deuterium-labeled analog of pyridoxine hydrochloride, also known as Vitamin B6. This compound primarily functions as a stable isotope, making it useful for metabolic studies and tracking biochemical pathways in research. Pyridoxine exhibits antioxidant properties and has been shown to exert protective effects in cellular models of Alzheimer's disease through the Nrf-2/HO-1 signaling pathway, highlighting its potential in neuroprotective research applications. -
Stable Isotope
3-Methyl-L-histidine-d3 is a deuterium-labeled derivative of the endogenous amino acid 3-Methyl-L-histidine. This compound is known to be incorporated into proteins, particularly actin and myosin, making it valuable for studies related to muscle function and protein metabolism. Its stable isotope labeling allows for enhanced tracking and quantification in metabolic research and isotopic labeling experiments, facilitating insights into amino acid turnover and protein synthesis pathways. -
Stable Isotope
L-Threonine-d2 is a stable isotope-labeled form of the amino acid L-Threonine. It serves as a valuable tool for biochemical research and applications in metabolic tracing and quantification studies. L-Threonine plays a critical role in protein synthesis and is essential in various physiological processes. Its stable isotope variant enables researchers to investigate metabolic pathways and protein dynamics with enhanced precision. -
Stable Isotope
L-Tryptophan-13C11,15N2 is a stable isotope-labeled form of the essential amino acid L-Tryptophan, featuring 13C and 15N isotopes. Serving as a precursor for key biomolecules such as serotonin, melatonin, and vitamin B3, this compound is valuable in metabolic studies and tracer experiments. Its isotopic labeling facilitates advanced research in nutritional biochemistry, pharmacology, and neurobiology, enabling precise tracking of metabolic pathways and compound interactions. -
Isotope Label
D-(+)-Trehalose-13C12 is a 13C isotope-labeled derivative of D-(+)-Trehalose, a naturally occurring disaccharide. This stable isotope variant is instrumental for metabolic studies, allowing for precise tracking of trehalose metabolism in biological systems. D-(+)-Trehalose is widely utilized as a food ingredient and pharmaceutical excipient, enhancing its relevance in both nutritional and therapeutic research applications. -
Stable Isotope
2-Ketoglutaric acid-d4 is a stable isotope form of 2-Ketoglutaric acid, functioning as a crucial intermediate in the Krebs cycle for ATP and GTP production. This reagent plays a pivotal role in nitrogen assimilation by providing carbon skeletons for various biological reactions. Furthermore, 2-Ketoglutaric acid-d4 serves as a reversible inhibitor of tyrosinase, exhibiting an IC50 of 15 mM, making it valuable for studies related to enzymatic activity and metabolic pathways. -
Stable Isotope
1-Methylhistamine-d3 dihydrochloride is a deuterated form of 1-Methylhistamine, serving as a stable isotope and a histamine metabolite. This compound is essential for studies involving histamine metabolism and receptor interactions. It is commonly utilized in pharmacological research and for the development of analytical techniques, such as mass spectrometry, to track histamine pathways in biological systems. -
Stable Isotope
4-Methylimidazole-d6 is the deuterated derivative of 4-Methylimidazole, serving as a stable isotope labeled compound. It is primarily utilized in isotope labeling studies and tracer experiments, allowing for enhanced detection and quantification in various chemical and biological research applications. This compound is essential for investigations involving metabolic pathways, structural biology, and the synthesis of isotopically labeled metabolites. -
Stable Isotope
Monoisobutyl phthalic acid-d4 is a deuterium-labeled derivative of Monoisobutyl phthalic acid, a notable phthalate metabolite found in human semen and meconium. This stable isotope serves as a useful tracer in metabolic studies and environmental exposure assessments. Its applications extend to analyzing phthalate exposure in biological samples, facilitating research in toxicology and epidemiology. -
Stable Isotope
6-keto Prostaglandin F1α-d4 is a deuterium-labeled analog of 6-keto Prostaglandin F1α. As a stable isotope, it serves as a valuable internal standard for quantitative mass spectrometry analyses of prostaglandins in biological samples. This compound supports research in prostaglandin metabolism and signaling pathways, facilitating studies related to inflammation, vascular function, and reproductive biology. -
Stable Isotope
DL-Glutamic acid-d5 is a deuterated analog of DL-Glutamic acid, a key metabolite in amino acid metabolism. This stable isotope offers enhanced stability compared to polymorphs α and β of L-Glutamic acid, making it valuable for trace analysis and metabolic studies. It is useful in research applications such as metabolic flux analysis and isotope labeling experiments, providing insights into metabolic pathways and biochemical processes. -
Stable Isotope
Uracil-d2 is a deuterated form of uracil, a naturally occurring pyrimidine derivative and one of the four essential nucleobases in RNA. As a stable isotope, Uracil-d2 is commonly utilized in nucleic acid research and metabolic studies, allowing for precise tracking and analysis in various biochemical pathways. Its incorporation into RNA molecules enables enhanced detection and quantification in techniques such as mass spectrometry and NMR spectroscopy. -
Stable Isotope
Hydrocinnamic acid-d5 is a deuterium-labeled derivative of hydrocinnamic acid, primarily utilized as a stable isotope in biochemical research. This compound serves as a significant growth regulator within the rhizosphere, playing a crucial role in plant development and interactions. Its applications include studying metabolic pathways, tracking the fate of metabolites, and investigating the ecological roles of growth regulators in plant biology. -
Stable Isotope
L-Alanine-d3-1 is a stable isotope-labeled form of the non-essential amino acid L-Alanine. This amino acid plays a crucial role in metabolic processes, particularly in sugar and acid metabolism, and is essential for energy production in muscle tissue and the central nervous system. L-Alanine-d3-1 is valuable for studies in metabolic research, isotope tracing, and providing insight into amino acid metabolism and immune response mechanisms. -
Stable Isotope
Cholesterol-13C5 is a stable isotope-labeled form of cholesterol, a primary sterol found in mammals that constitutes 20-25% of the plasma membrane's structural components. It plays a critical role in regulating membrane fluidity and permeability, influencing the functionality of transporters and signaling proteins. Additionally, cholesterol acts as an agonist for the estrogen-related receptor α (ERRα), making it valuable for research in cell membrane dynamics and receptor interaction studies. This reagent is essential for tracing studies and metabolic research involving cholesterol metabolism. -
Stable Isotope
Hypoxanthine-13C2,15N is a stable isotope-labeled purine derivative with both 13C and 15N isotopes. This compound serves as a potential generator of free radicals and can be utilized as a biomarker for hypoxia in various biological systems. It is particularly useful in metabolic studies and investigations involving hypoxic conditions, allowing researchers to trace metabolic pathways and understand cellular responses to low oxygen levels. -
Stable Isotope
3-Hydroxyanthranilic acid-d3 is a deuterium-labeled analog of 3-Hydroxyanthranilic acid, utilized as a stable isotope in research. This compound serves as a valuable tracer in metabolic studies and is instrumental in elucidating biochemical pathways involving tryptophan metabolism. Its stable isotope properties enable precise quantification in various analytical techniques, including mass spectrometry. -
Stable Isotope
D-Valine-d8 is a deuterated form of D-Valine, the enantiomer of L-Valine, which is one of the 20 standard amino acids used in protein synthesis. The incorporation of stable isotopes, such as deuterium, in D-Valine-d8 allows for advanced tracing applications in metabolic studies and quantitative analyses in mass spectrometry. This reagent is essential for research exploring amino acid metabolism, protein interaction dynamics, and for labeling studies in various biological systems. -
Stable Isotope
Thymine-d4-1 is a deuterated form of thymine, a nucleobase essential to DNA structure and function. This stable isotope is utilized in research applications that require isotopic labeling, including studies on nucleic acid metabolism and the effects of chemotherapeutic agents like 5-fluorouracil (5-FU), which targets thymine with a Km of 2.3 μM. Its incorporation into molecular studies can aid in elucidating biological pathways and drug mechanisms in cancer research. -
Stable Isotope
1-Palmitoyl-sn-glycero-3-phosphocholine-d31 is a deuterated stable isotope of 1-Palmitoyl-sn-glycero-3-phosphocholine, a prominent lysophosphatidylcholine with notable proinflammatory properties. This reagent is valuable for research applications focusing on lipid metabolism, cell signaling, and the pathophysiology of conditions such as atherosclerosis. The introduction of deuterium enables enhanced quantification and tracking of metabolic processes in various biological systems. -
Stable Isotope
(±)-1,2-Propanediol-d8 is a deuterium-labeled form of (±)-1,2-Propanediol, an aliphatic alcohol known for its role as a solvent and stabilizing agent in various formulations. This stable isotope is particularly valuable for enhancing the solubility and stability of other compounds in analytical and pharmacological studies. Its applications extend to tracer studies and metabolic pathway investigations, making it an essential reagent in chemical research and development. -
Stable Isotope
D-Ribose-13C is a stable isotope-labeled form of D-Ribose, crucial for metabolic studies. As a key component of adenosine triphosphate (ATP), D-Ribose plays a significant role in cellular energy production and is utilized in metabolic therapy for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Its incorporation into research enables the investigation of metabolic pathways and protein glycation processes. -
Stable Isotope
L-Serine-13C3,15N,d3 is a stable isotope-labeled form of L-Serine, featuring deuterium (d3), carbon-13 (13C3), and nitrogen-15 (15N) isotopes. This non-essential amino acid is crucial for numerous biological processes, including cellular proliferation and amino acid biosynthesis. It serves as a valuable tool in metabolic studies, stable isotope labeling experiments, and tracer studies to investigate metabolic pathways and protein synthesis. -
Stable Isotope
7-Dehydrocholesterol-d7 is a deuterium-labeled form of 7-dehydrocholesterol, a crucial biosynthetic precursor in the synthesis of cholesterol and vitamin D3. This stable isotope is utilized in metabolic studies and tracer experiments to investigate biochemical pathways involving cholesterol metabolism and vitamin D synthesis. Its deuterium labeling enables precise quantification and tracking in complex biological systems. -
Stable Isotope
Ethynyl Estradiol-13C2 is a stable carbon isotope-labeled form of Ethynyl Estradiol, featuring a terminal alkyne group. This compound serves as a valuable reagent for click chemistry applications, specifically facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing substrates. Its ability to act as a tracer in biological studies enables researchers to investigate metabolic pathways and interactions involving estrogenic activity. -
Stable Isotope
1-Hexadecanol-d5 is a deuterated form of 1-Hexadecanol, serving as a stable isotope for chemical research. As a fatty alcohol, it exhibits lipophilic properties, making it useful in various biological and biochemical studies. Its application in isotopic labeling enables researchers to track metabolic pathways and investigate lipid metabolism in cellular models. -
Stable Isotope
L-Proline-13C is a stable isotope-labeled form of L-Proline, an amino acid critical for protein synthesis in living organisms. The incorporation of carbon-13 enables tracing and metabolic studies, making it a valuable tool for research in protein dynamics and metabolic pathways. L-Proline-13C is useful in applications such as NMR spectroscopy and mass spectrometry to investigate biochemical processes and amino acid metabolism. -
Stable Isotope
L-Tyrosine-4-13C is a stable isotope-labeled form of L-Tyrosine, a non-essential amino acid involved in neurotransmitter synthesis. This compound serves as a valuable tracer in metabolic studies and isotopic labeling experiments. Additionally, L-Tyrosine-4-13C can be used to investigate its effects on metabolic pathways, such as the inhibition of citrate synthase activity in the posterior cortex. -
Stable Isotope
Glycerol-d5 is a deuterated form of glycerol, serving as a stable isotope used in various biochemical applications. It is frequently utilized in sample preparation and gel formation for polyacrylamide gel electrophoresis, providing enhanced resolution and accuracy in the analysis of biomolecules. Its incorporation into experimental protocols aids in tracking molecular pathways and studying metabolic processes. -
Stable Isotope
L-Leucine-2-13C,15N is a stable isotope-labeled form of the essential branched-chain amino acid L-Leucine. This compound primarily targets the mTOR signaling pathway, playing a critical role in protein synthesis and cell growth. It is valuable in metabolic studies, tracking amino acid utilization, and investigating metabolic disorders. L-Leucine-2-13C,15N is useful for researchers exploring the effects of amino acids on cellular processes in various biological contexts. -
Stable Isotope
D-Glucose-d4 is a deuterium-labeled form of D-Glucose, a fundamental monosaccharide involved in various biological processes. This stable isotope is essential for metabolic studies and tracer applications in research, facilitating the investigation of glucose metabolism and metabolic flux analysis. Its unique labeling enables precise tracking in biological systems, making it invaluable for biochemical and pharmacological studies. -
Stable Isotope
3-Indoleacetic acid-d4 is a deuterium-labeled derivative of 3-Indoleacetic acid, a potent plant growth hormone classified as an auxin. This stable isotope is utilized in research applications to study plant cell biology, as it promotes cell elongation and division when added to cell culture media. Its isotopic labeling allows for precise tracking and analysis in various experimental settings, enhancing the understanding of plant development and hormonal pathways. -
Stable Isotope
L-5-Hydroxytryptophan-d4 is a deuterated form of L-5-Hydroxytryptophan (L-5-HTP), which serves as a stable isotope for analytical applications. As the direct precursor to serotonin, L-5-HTP plays a crucial role in neurotransmitter synthesis and exhibits potential benefits in mood regulation, appetite control, and sleep enhancement. This compound is widely utilized in research to investigate its therapeutic effects in conditions such as fibromyalgia, myoclonus, migraines, and cerebellar ataxia. -
Stable Isotope
Menadione-d3 is a deuterium-labeled analogue of Menadione, a synthetic naphthoquinone precursor. This compound serves as a stable isotope, facilitating research into vitamin K metabolic pathways. Menadione can be bioactivated to form vitamin K2 in vivo, making Menadione-d3 valuable for studies on vitamin K's biological functions and its role in coagulation and bone metabolism. -
Stable Isotope
Bisphenol A-d14 is a deuterated form of Bisphenol A, serving as a stable isotope for research applications. This compound, a prominent phenolic synthetic derivative, is commonly implicated in the production of polycarbonate plastics and epoxy resins. As an endocrine-disrupting chemical, Bisphenol A-d14 can aid in the study of its reproductive, developmental, and systemic toxic effects, contributing to the understanding of its role in various diseases, including cardiovascular, respiratory, and metabolic disorders. -
Stable Isotope
Paraxanthine-13C4,15N3 is a stable isotope-labeled form of the caffeine metabolite, Paraxanthine, featuring four 13C and three 15N isotopes. This compound is recognized for its neuroprotective properties, particularly in safeguarding dopaminergic neurons from cell death by stimulating Ryanodine Receptor Channels. Paraxanthine-13C4,15N3 is valuable in biochemical research, metabolic studies, and tracing studies involving caffeine metabolism and pharmacology. -
Stable Isotope
Vitamin K1-d7 is a deuterium-labeled derivative of Vitamin K1, primarily utilized as a stable isotope in research applications. As a naturally occurring vitamin, Vitamin K1 is essential for blood coagulation as well as bone and vascular metabolism. The labeled form enables precise tracking and analysis in metabolic studies, enhancing understanding of Vitamin K's physiological roles and interactions in various biological processes. -
Stable Isotope
L-Hexanoylcarnitine-d3 chloride is a stable isotope-labeled form of L-Hexanoylcarnitine chloride, incorporating deuterium for enhanced tracking in metabolic studies. This reagent serves as a valuable tool in the investigation of carnitine metabolism and fatty acid oxidation pathways. Its application in research includes the study of mitochondrial function, lipid metabolism, and potential therapeutic targets in metabolic disorders. -
Stable Isotope
Isovaleric acid-d9 is a deuterated stable isotope of isovaleric acid. This natural fatty acid has been implicated in neonatal death and is associated with Jamaican vomiting sickness in humans. Isovaleric acid-d9 serves as a valuable tool in metabolic studies and pharmacokinetic research, enabling investigators to trace metabolic pathways and assess the effects of isovaleric acid in biological systems. -
Stable Isotope
Elaidic acid-d9 is a deuterium-labeled derivative of elaidic acid, primarily utilized as a stable isotope in research applications. Elaidic acid, the predominant trans fatty acid in hydrogenated vegetable oils, serves as a pharmaceutical solvent, aiding in the delivery and formulation of drug compounds. This stable isotope can be essential for tracer studies and metabolic research, providing insights into lipid metabolism and trans fat dynamics in biological systems. -
Stable Isotope
L-Tyrosine-1-13C is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine. This compound is utilized in metabolic studies and tracer experiments due to its ability to participate in various biosynthetic pathways. Additionally, L-Tyrosine-1-13C can inhibit citrate synthase activity in the posterior cortex, making it a valuable tool for investigating metabolic processes and neurobiological research. -
Stable Isotope
L-Methionine-1-13C is a stable isotope-labeled form of L-Methionine, the L-isomer of the essential amino acid Methionine. As a crucial component in protein synthesis, Methionine serves various roles in supporting cellular function, including acting as a hepatoprotectant. This reagent is valuable in metabolic studies and tracing experiments, facilitating insights into amino acid metabolism and its physiological implications. -
Stable Isotope
Arabinose-d is a deuterium-labeled form of arabinose, a naturally occurring pentose sugar involved in various biological processes. This stable isotope is utilized in metabolic studies and tracer experiments, enabling researchers to trace metabolic pathways and analyze carbohydrate metabolism with enhanced precision. Arabinose-d serves as an important tool in biochemical research aimed at understanding glycan structures and functions. -
Stable Isotope
L-Homoarginine-13C7,15N4 hydrochloride is a stable isotope-labeled analog of the endogenous metabolite H-HomoArg-OH.HCl. Incorporating 13C and 15N isotopes, this compound is useful in metabolic studies and biochemical research. Its stable isotopic profile enables precise tracking of metabolic processes and interactions in biological systems. -
Stable Isotope
Phenylglyoxylic acid-d5 is a deuterium-labeled analog of phenylglyoxylic acid, functioning primarily as a stable isotope. This compound serves as a biomarker for human exposure to ethylbenzene and styrene, making it valuable in environmental and toxicological research. Additionally, phenylglyoxylic acid-d5 can be utilized as an intermediate in the synthesis of antineoplastic agents, contributing to cancer research and drug development efforts. -
Stable Isotope
L-Serine1-13C,15N is a stable isotope-labeled form of L-Serine, incorporating both 13C and 15N isotopes. As a non-essential amino acid, L-Serine is crucial for various metabolic processes, including cellular proliferation and neurotransmitter synthesis. This labeled compound serves as a valuable tool in metabolic studies, providing insights into amino acid metabolism and the physiological roles of serine in biological systems.
