Isotope-Labeled Compounds

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  1. Stable Isotope

    L-Tyrosine-13C,15N is a stable isotope-labeled version of L-Tyrosine, incorporating both carbon-13 and nitrogen-15 isotopes. L-Tyrosine is a non-essential amino acid that plays a critical role in protein synthesis and neurotransmitter production. This isotopic labeling is valuable for metabolic research and tracer studies, enabling the tracking of metabolic pathways and the investigation of amino acid dynamics in various biological systems.
  2. Stable Isotope

    Hippuric acid-15N is a stable isotope-labeled form of hippuric acid, which is 2-benzamidoacetic acid. This compound is produced through the conjugation of benzoic acid and glycine and serves as a primary metabolite of aromatic compounds derived from dietary intake. Hippuric acid-15N is utilized in research applications such as metabolic profiling, tracer studies, and studies investigating the metabolism and excretion of aromatic substances.
  3. Stable Isotope

    Tetradecanoylcarnitine-d9 is a deuterium-labeled derivative of Tetradecanoylcarnitine, a critical human metabolite that participates in the β-oxidation of long-chain fatty acids. This stable isotope is valuable for metabolic studies, allowing for precise tracing of lipid metabolism and fatty acid utilization in biological systems. Its application spans various research areas, including metabolic disorders and energy homeostasis.
  4. Stable Isotope

    Methoxyacetic acid-d3 is a deuterated derivative of Methoxyacetic acid, primarily utilized as a stable isotope label in chemical research. It serves as a metabolite of ethylene glycol monomethyl ether and exhibits the capacity to inhibit respiratory functions in hepatic and testicular mitochondria at elevated concentrations. Its use in studies of mitochondrial dynamics, toxicology, and metabolic pathways provides valuable insights into cellular function and potential toxicity mechanisms.
  5. Stable Isotope

    Glutaric acid-d2 is a stable isotope-labeled form of glutaric acid, a C5 dicarboxylic acid involved in the catabolism of lysine and tryptophan. This compound plays a significant role in biological processes, influencing pericyte contractility and migration. Glutaric acid-d2 serves as a valuable tool for research applications in metabolic studies and diagnostic assessments related to glutaric aciduria type I.
  6. Stable Isotope

    Decanedioic acid-d16 is a deuterium-labeled derivative of decanedioic acid, a straight-chain dicarboxylic acid. This compound exhibits significant biological activity, particularly in the context of metabolic regulation, and has been shown to prevent and reverse metabolic-associated liver disease and obesity. Research applications include studies on metabolic inflexibility in type 2 diabetes, as well as investigations into conditions related to carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.
  7. Stable Isotope

    Estrone sulfate-d5 sodium is a deuterium-labeled derivative of estrone sulfate, serving as a stable isotope for metabolic studies. As an inactive endogenous estrogen, it can be converted into active forms, estrone and estradiol, through various biological processes. Estrone sulfate-d5 sodium acts as a substrate for the OATP1B3 transporter and is involved in mammary tumor growth in models of breast cancer. This compound is valuable for research into estrogen metabolism and its role in breast cancer pathophysiology.
  8. Stable Isotope

    3-Hydroxybutyric acid-13C2 sodium is a stable isotope-labeled derivative of 3-Hydroxybutyric acid sodium. This metabolite has been shown to be elevated in type I diabetes and plays a crucial role in modulating the properties of membrane lipids. It is valuable for metabolic research, particularly in studies investigating diabetes mechanisms and lipid metabolism.
  9. Stable Isotope

    Dodecanedioic Acid-13C12 is a stable isotope-labeled version of dodecanedioic acid, functioning as an alternative energy substrate in metabolic studies. This straight-chain dicarboxylic acid is known for its ability to enhance oxidation during physical exertion, thereby mitigating muscle fatigue without causing insulin secretion. Moreover, it demonstrates potential in lowering blood glucose levels in models of non-insulin-dependent diabetes mellitus, making it a valuable reagent for metabolic and diabetes research.
  10. Stable Isotope

    N-Palmitoyl-D-sphingomyelin-13C is a stable isotope-labeled form of N-Palmitoyl-D-sphingomyelin. This compound plays a critical role in lipid nanoparticle synthesis, making it vital for research in drug delivery systems and nanomedicine. The incorporation of the deuterated label allows for precise tracking and analysis of sphingolipid dynamics in biological studies.
  11. Stable Isotope

    1,4-Dimethoxybenzene-d10 is the deuterated form of 1,4-Dimethoxybenzene, a compound recognized as an endogenous metabolite. This stable isotope is utilized in various research applications, including metabolic studies and tracer experiments. It serves as a valuable tool for investigating metabolic pathways and enhancing the accuracy of analytical techniques in chemical research.
  12. Stable Isotope

    D-Lyxose-13C-4 is a stable isotopically labeled form of D-Lyxose, an endogenous metabolite that serves as a rare pentose sugar. This compound plays a crucial role in the synthesis of various pharmaceutical agents, including anti-tumor drugs like alpha-galactose ceramide immunostimulants, and L-nucleoside analogs used for antiviral drug development. Furthermore, D-Lyxose can be employed as a synthetic intermediate for producing other rare sugars, such as L-ribose, enhancing its utility in chemical and biological research applications.
  13. Stable Isotope

    Arabinose-d-1 is a deuterium-labeled form of arabinose, a naturally occurring sugar in metabolic pathways. This stable isotope is useful for tracer studies and metabolic research, allowing for precise tracking of metabolic processes in various biological systems. Its applications extend to investigating carbohydrate metabolism and the role of arabinose in cellular functions.
  14. Stable Isotope

    Lignoceric acid-d9 is a deuterated derivative of lignoceric acid, a long-chain saturated fatty acid (Tetracosanoic acid) comprised of 24 carbon atoms. This stable isotope is prevalent in the developing brain and serves as a by-product of lignin metabolism. Lignoceric acid-d9 is primarily utilized in research focused on Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy, aiding in the investigation of metabolic pathways and disease mechanisms associated with these conditions.
  15. Stable Isotope

    1-Arachidoyl-sn-glycero-3-phosphocholine-d4 is a deuterium-labeled lysophospholipid, specifically 1-Arachidoyl-sn-glycero-3-phosphocholine. This stable isotope is utilized in various biochemical research applications, particularly in mass spectrometry and metabolic studies. Due to its labeled nature, it serves as an effective internal standard for analyzing lipid metabolism and profiling in complex biological samples.
  16. Stable Isotope

    1,5-Anhydrosorbitol-13C is a stable isotope-labeled form of 1,5-Anhydrosorbitol, which serves as a short-term biomarker for glycemic control. This compound is utilized in metabolic studies and provides insight into carbohydrate metabolism and insulin sensitivity. Its isotopic labeling facilitates precise quantification and tracking in various biological research applications.
  17. Stable Isotope

    Stearoylcarnitine-d3-1 hydrochloride is a deuterium-labeled derivative of stearoylcarnitine, a naturally occurring fatty ester lipid metabolite in humans. This compound is utilized as a stable isotope in metabolomics research, particularly as a biomarker for early-onset and late-onset preeclampsia. Its application in metabolic studies supports the understanding of lipid metabolism and related pathophysiological conditions.
  18. Stable Isotope

    D-Glucose-d2-1 is a deuterium-labeled derivative of D-Glucose, a key monosaccharide in biological systems. As a primary energy source, D-Glucose plays a vital role in various metabolic pathways and cellular signaling. This stable isotope is particularly useful in metabolic tracing studies, as well as in research involving carbohydrate metabolism and biochemical analysis.
  19. Stable Isotope

    Ercalcidiol-13C3 is a stable isotope labeled form of Ercalcidiol, specifically 25-Hydroxy Vitamin D2-13C3. This compound serves as a biomarker for assessing vitamin D nutritional status in various biological samples. Its application in metabolic studies allows researchers to trace vitamin D metabolism and its biological implications in health and disease.
  20. Stable Isotope

    1,3-Dimethyluric acid-13C4,15N3 is a stable isotope-labeled form of 1,3-Dimethyluric acid, incorporating four carbon-13 and three nitrogen-15 isotopes. This compound serves as a significant product of theophylline metabolism in humans and is recognized as a purine component found in urinary calculi. Its stable isotope labeling facilitates research in metabolic pathways and biomarker discovery, enhancing studies related to renal health and purine metabolism.
  21. Stable Isotope

    D-Ribose-d-2 is a deuterium-labeled derivative of D-Ribose. Its primary role is to serve as a stable isotope, enabling advanced metabolic studies. D-Ribose is integral to ATP synthesis and plays a significant role in energy metabolism, making it useful in research focusing on chronic fatigue syndrome and cardiac energy dynamics. This compound is essential for tracing metabolic pathways and understanding energy-related disorders.
  22. Stable Isotope

    Stachydrine-d6 is a deuterated form of Stachydrine, a compound known for its role in promoting blood circulation and alleviating blood stasis, particularly in the traditional Chinese herb Leonurus heterophyllus. This stable isotope can be used in tracing studies and metabolic research due to its labeled nature. Additionally, Stachydrine exhibits inhibitory effects on the NF-κB signaling pathway, highlighting its potential in studies related to inflammation and immunity.
  23. Stable Isotope

    Hydrocinnamic acid-2,3-13C2 is a stable isotope-labeled form of hydrocinnamic acid, primarily utilized as a tracer in metabolic studies. This compound is recognized for its role as a rhizospheric signaling molecule, affecting plant growth and development. Researchers can employ Hydrocinnamic acid-2,3-13C2 in studies investigating plant interactions, growth regulation, and biochemical pathways involving aromatic compounds.
  24. Stable Isotope

    Uracil-13C is a stable isotope-labeled variant of uracil, a naturally occurring pyrimidine derivative and one of the four nucleobases found in RNA. This compound is commonly utilized in metabolic studies and tracer experiments to investigate RNA synthesis and turnover. Its stable isotope labeling enhances the sensitivity and accuracy of analytical techniques, making it a valuable tool in biochemical research and diagnostics.
  25. Stable Isotope

    17α-Hydroxyprogesterone-13C3 is a stable isotope-labeled form of 17α-Hydroxyprogesterone, an endogenous progestogen and key intermediary in the biosynthesis of steroid hormones. This compound plays a crucial role in the production of corticosteroids, androgens, and estrogens. Its application in research includes studying steroid hormone metabolism and dynamics, providing a valuable tool for tracing hormone pathways in biological systems.
  26. Stable Isotope

    N-Acetylserine-d3 is a deuterium-labeled form of N-Acetylserine, a physiological inducer of cysteine biosynthesis and an activator of the CysB transcription factor. It plays a critical role in promoting cysJIH transcription in vitro and demonstrates binding affinity for the CysB apoprotein. This stable isotope is valuable for research applications, including studies related to SARS-CoV-2 infection.
  27. Stable Isotope

    2-(tert-Butyl)-4-methoxyphenol-d3 is a deuterium-labeled derivative of 2-(tert-Butyl)-4-methoxyphenol, serving as a stable isotope. This compound is valuable for applications in tracing and metabolic studies in biological research. Its isotopic labeling allows for precise quantification and analysis in various experimental settings, enhancing the understanding of biochemical pathways and drug interactions.
  28. Stable Isotope

    N4-Acetylsulfamerazine-d4 is a deuterium-labeled derivative of N4-Acetylsulfamerazine, classified as a sulfonamide. This stable isotope is primarily utilized in metabolic studies and pharmacokinetic research, facilitating the tracing of molecular pathways in biological systems. It serves as a valuable tool for understanding the behavior and dynamics of sulfonamide compounds in various experimental settings.
  29. Stable Isotope

    D-Ribose-d-1 is a deuterium-labeled derivative of D-Ribose, primarily utilized as a stable isotope in metabolic research. D-Ribose plays a crucial role in cellular energy production as a component of ATP, and is commonly employed in metabolic therapy applications, particularly in addressing chronic fatigue syndrome and enhancing cardiac energy metabolism. Its biochemical properties make it a valuable tool for studying metabolic pathways and energy dynamics in various biological systems.
  30. Stable Isotope

    5-Methyluridine-2′-13C is a stable isotope-labeled form of 5-Methyluridine, an endogenous methylated nucleoside observed in human influenza. This compound can be utilized in metabolic studies and tracer experiments to investigate nucleoside metabolism, RNA synthesis, and related biological pathways. Its incorporation of the stable isotope allows for precise quantification and tracking of metabolic processes in various biological systems.
  31. Stable Isotope

    D-Galactose-d-2 is a stable isotope-labeled form of D-Galactose, an aldohexose and C-4 epimer of glucose. This compound is utilized in metabolic studies and tracing experiments due to its ability to participate in glycolytic and galactose metabolism pathways. Its unique isotopic labeling enables precise quantification and investigation of biochemical processes involving galactose.
  32. Stable Isotope

    D-Glucose-13C,d is a stable isotope-labeled form of D-Glucose, featuring both deuterium and carbon-13. As a crucial monosaccharide, D-Glucose plays a vital role in carbohydrate metabolism and energy production. This compound is commonly utilized in metabolic studies, tracing pathways in biochemical research, and investigating cellular processes involving glucose utilization and metabolism.
  33. Stable Isotope

    5-Hydroxymethyl-2-furancarboxylic acid-13C6 is a stable isotope-labeled derivative of 5-Hydroxymethyl-2-furancarboxylic acid. This compound serves as a key metabolite of 5-hydroxymethyl-2-furfural (HMF) in biological systems and is primarily excreted via renal pathways. It is utilized in metabolic studies and tracer experiments to investigate the pharmacokinetics and metabolism of HMF and related compounds.
  34. Stable Isotope

    D-Galactose-13C-5 is a stable isotope-labeled form of D-Galactose, an aldohexose and C-4 epimer of glucose. This reagent is instrumental in metabolic studies and tracing experiments, enabling researchers to investigate carbohydrate metabolism and cellular processes. Its labeling allows for enhanced detection and quantification in various biochemical assays, making it a vital tool in metabolic research and nutrition studies.
  35. Stable Isotope

    L-Serine-2-13C is a stable isotope-labeled form of L-Serine, an important non-essential amino acid. This compound is critical for various biological processes, including cellular proliferation and neurotransmitter synthesis. L-Serine-2-13C is utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and related biochemical pathways.
  36. Stable Isotope

    2-Methylsuccinic acid-d6 is a deuterium-labeled derivative of 2-Methylsuccinic acid, a naturally occurring metabolite found in human biological fluids. This compound is significant for metabolic studies and serves as a biochemical marker in the diagnosis and research of ethylmalonic encephalopathy. Its stable isotope labeling improves the accuracy of analytical methods in metabolic profiling and tracer studies in various biological contexts.
  37. Stable Isotope

    C22 Phytoceramide-d3 (t18:0/22:0) is a deuterated form of C22 Phytoceramide, a sphingolipid that plays a critical role in cellular signaling and membrane structure. Isolated from Moro blood orange (C. sinensis) peels and primary human astrocytes, this stable isotope is ideal for metabolic studies and tracing lipid pathways in biological systems. Its application extends to research in neurobiology and cellular metabolism, enhancing the understanding of sphingolipid dynamics.
  38. Stable Isotope

    5-Hydroxytryptamine-d4 creatinine sulfate monohydrate is a stable isotope-labeled form of the endogenous metabolite, 5-Hydroxytryptamine creatinine sulfate monohydrate. This reagent is primarily used in biological research to facilitate precise quantification in mass spectrometry applications. Its deuterium labeling enhances detection sensitivity and accuracy in metabolic studies and pharmacokinetic investigations involving serotonin pathways.
  39. Stable Isotope

    D-Glucose-13C,d-1 is a stable isotope-labeled form of D-Glucose, incorporating both deuterium and carbon-13 isotopes. As a essential monosaccharide, D-Glucose plays a vital role in carbohydrate metabolism and serves as a primary energy source in biological systems. This isotope-labeled reagent is especially valuable for metabolic flux analysis, tracer studies, and various applications in biochemistry and cellular biology, enabling researchers to investigate metabolic pathways and dynamic cellular processes with enhanced precision.
  40. Stable Isotope

    (E)-2-Methylbut-2-enoic-4,4,4-d3 acid is a deuterated analog of tiglic acid, a monocarboxylic unsaturated organic acid naturally present in croton oil and various botanical sources. This stable isotope-labeled compound serves as a useful tool in metabolic studies, allowing for the tracing of metabolic pathways and the investigation of plant metabolite functions. Its unique isotopic signature enhances sensitivity and specificity in analytical applications such as mass spectrometry.
  41. Stable Isotope

    L-Threonine-13C4,15N,d5 is a stable isotope-labeled form of the amino acid L-Threonine, featuring deuterium and isotopes of carbon and nitrogen. This compound is utilized in various applications, including metabolic studies and isotopic labeling experiments, enabling researchers to track metabolic pathways and protein synthesis. Its natural occurrence and potential for production via microbial fermentation make it a valuable reagent for investigations in nutrition, pharmaceuticals, and animal feed research.
  42. Stable Isotope

    Propane-1,2,3-triyl tripalmitate-d98 is a deuterium-labeled derivative of propane-1,2,3-triyl tripalmitate, a recognized endogenous metabolite. This stable isotope is primarily utilized in metabolic studies, serving as a tracer in various biological assays and investigations. Its distinct isotopic composition enhances the precision of analytical techniques, facilitating the exploration of lipid metabolism and related biochemical pathways.
  43. Stable Isotope

    D-Fructose-3-13C is a stable isotope-labeled form of D-Fructose, a naturally occurring monosaccharide prevalent in various plants. This isotope is employed in metabolic research to trace carbohydrate pathways and study metabolic flux in biological systems. D-Fructose-3-13C serves as a valuable tool for investigators exploring carbohydrate metabolism and related biochemical processes.
  44. Stable Isotope

    Xylose-d-4 is a stable isotope labeled form of xylose, specifically containing deuterium at the 4-position. This compound is utilized in metabolic studies as a tracer in carbohydrate metabolism assessment and can aid in understanding the role of xylose in biochemical pathways. Its isotopic labeling enhances sensitivity in analytical techniques, making it a valuable tool for research applications in nutrition, metabolism, and cellular processes.
  45. Stable Isotope

    Cholesteryl palmitate-d31 is a deuterium-labeled derivative of cholesteryl palmitate, serving as a stable isotope for biochemical studies. This compound is valuable in research to explore its role as a prognostic biomarker for chronic interstitial pneumonia (CIP). Its stable isotopic nature allows for precise quantitative analysis in metabolic studies and tracking lipid metabolism in cellular models.
  46. Stable Isotope

    N-Isovalerylglycine-d9 is a deuterated form of N-Isovaleroylglycine, functioning as a stable isotope for research applications. This acyl glycine serves as a potential biomarker for predisposition to weight gain and obesity, aiding in the investigation of metabolic disorders. Researchers can utilize N-Isovalerylglycine-d9 to explore the biochemical pathways associated with energy metabolism and fat accumulation.
  47. Stable Isotope

    5-Hydroxyindole-3-acetic acid-13C6 is a stable isotope-labeled form of 5-Hydroxyindole-3-acetic acid, the principal metabolite of serotonin and metanephrines. This compound serves as a valuable biomarker for neuroendocrine tumors, aiding in the quantitative analysis of serotonin metabolism and its pathological implications. Its applications extend to various research fields, including oncology and neurobiology, where precise metabolic tracking is essential.
  48. Stable Isotope

    D-Glucose-13C,d2 is a stable isotope-labeled form of D-Glucose, featuring deuterium and carbon-13 isotopes. As a fundamental monosaccharide, D-Glucose plays a crucial role in biological processes, functioning as a primary energy source and a key player in metabolic pathways. This isotopically enriched compound is valuable for metabolic studies, tracer experiments, and investigations into glucose metabolism, enabling enhanced tracking and quantification in various research applications.
  49. Stable Isotope

    2'-Deoxycytidine-13C monohydrate is a stable isotope-labeled analog of 2'-Deoxycytidine, where the carbon atoms are isotopically enriched with carbon-13. This reagent is primarily utilized in metabolic studies and tracer experiments to investigate nucleotide metabolism and DNA synthesis pathways. It serves as a valuable tool for researchers exploring cellular metabolism, epigenetics, and the effects of nucleoside analogs in various biological systems.
  50. Stable Isotope

    D-Ribose-13C-3 is a stable isotope-labeled form of D-Ribose, which serves as a key precursor for ATP synthesis. As an energy enhancer, D-Ribose plays a vital role in cellular metabolism, particularly in conditions of chronic fatigue syndrome and cardiac energy deficits. This reagent is commonly utilized in metabolic research and studies involving protein glycation processes.

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