Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Methyl 2-(1H-indol-3-yl)acetate-d5 is the deuterated derivative of Methyl 2-(1H-indol-3-yl)acetate, a stable isotope used in biochemical research. As an endogenous metabolite, it plays a crucial role in metabolic pathways, enabling researchers to investigate these processes using mass spectrometry and NMR spectroscopy. This labeled compound is essential for studying synthesis, degradation, and the metabolism of indole derivatives in various biological systems. -
Stable Isotope
Dihomo-γ-linolenic acid-d6 is a deuterium-labeled analog of Dihomo-γ-linolenic acid (DGLA), a 20-carbon omega-6 fatty acid known for its anti-inflammatory and anti-proliferative properties. DGLA plays a significant role in lipid metabolism and is involved in cellular signaling pathways. This stable isotope is particularly useful in metabolic research and tracer studies, enabling precise tracking of fatty acid metabolism and its effects in various biological systems, including the investigation of atherosclerosis in model organisms. -
Stable Isotope
Leukotriene E4-d5 is a deuterium-labeled analog of Leukotriene E4, a potent inflammatory mediator produced by the enzymatic conversion of LTD4 through dipeptidase activity. It serves as a key constituent of slow-reacting substance of anaphylaxis (SRS-A) and is implicated in various inflammatory responses. This stable isotope is particularly useful in research applications for studying asthma and other respiratory conditions, as it allows for accurate measurement of Leukotriene E4 levels in biological samples, including plasma and urine. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-13C3 is a stable isotope-labeled variant of propane-1,2,3-triyl tripalmitate, an endogenous metabolite involved in lipid metabolism. The incorporation of the stable carbon-13 isotope allows for precise tracking and quantification in metabolic studies. This reagent is valuable for research applications focused on lipid profiling, metabolic pathways, and the dynamics of fatty acid metabolism. -
Stable Isotope
L-Alanine-1-13C is a stable isotope-labeled form of the non-essential amino acid L-Alanine. It plays a crucial role in metabolism, particularly in the synthesis and degradation of sugars and organic acids. This compound can be utilized in metabolic studies, tracer experiments, and analyses of metabolic pathways, aiding in the understanding of amino acid functions and energy provision in muscle, brain, and central nervous system tissues. -
Isotope-Labeled Compounds
(±) Anabasine-d4 is a deuterated analog of (±) Anabasine, serving as a useful isotope-labeled compound. This racemic mixture acts as an agonist of the α7 nicotinic acetylcholine receptor (α7nAChR), demonstrating notable anti-inflammatory properties and insecticidal activity. It is suitable for applications in pharmacological research, particularly studies involving receptor activation and inflammatory responses. -
Stable Isotope
Estriol-d2 is a deuterated form of estriol, serving as a stable isotope for research applications. It functions as an antagonist of G-protein coupled estrogen receptors, particularly in estrogen receptor-negative breast cancer cells. This compound is valuable for studying estrogen signaling pathways and developing therapeutic strategies in hormone-related cancers. Its isotopic labeling also enhances analytical techniques such as mass spectrometry for investigating biological processes. -
Stable Isotope
p-Coumaric acid-13C3 is a stable isotope-labeled form of p-Coumaric acid, an isomer of cinnamic acid. This compound exhibits notable antitumor and anti-mutagenic properties, making it useful in cancer research and studies focused on mutagenesis. p-Coumaric acid-13C3 serves as a valuable tool for metabolic studies and tracking biological processes involving phenolic compounds. -
Stable Isotope
L-Serine-d2 is a deuterium-labeled form of the non-essential amino acid L-Serine. This stable isotope plays a vital role in cellular proliferation, serving as a precursor for proteins and neurotransmitters. L-Serine-d2 is utilized in metabolic studies and tracer experiments, providing insights into biochemical pathways and amino acid metabolism in various research applications. -
Stable Isotope
Isovaleric acid-13C is a stable isotope-labeled variant of isovaleric acid. This naturally occurring fatty acid is significant in metabolic studies and has implications in various biological processes, including its association with neonatal death and Jamaican vomiting sickness. It serves as a useful tracer in research involving metabolic pathways, lipid metabolism, and the study of disorders related to fatty acid metabolism. -
Stable Isotope
Sodium 3-methyl-2-oxobutanoate-d7 is a deuterium-labeled variant of Sodium 3-methyl-2-oxobutanoate, serving as a stable isotope. This compound functions as a key precursor of pantothenic acid in Escherichia coli, facilitating studies on metabolic pathways and bacterial biosynthesis. Its unique isotopic properties make it suitable for tracer experiments and quantitative analysis in metabolic research. -
Stable Isotope
Disodium succinate-d4 is a deuterium-labeled derivative of disodium succinate. As a stable isotope, it serves as a valuable tracer in metabolic studies, particularly in the tricarboxylic acid cycle. This compound can be utilized in various research applications, including metabolic flux analysis and isotopic labeling experiments in both aerobic and anaerobic metabolism. -
Stable Isotope
L-Tyrosine-3,5-13C2 is a stable isotope of the non-essential amino acid L-Tyrosine, featuring carbon-13 labeling at the 3 and 5 positions. This compound can be utilized to investigate metabolic pathways and enzyme interactions, specifically in studies assessing the inhibition of citrate synthase activity in the posterior cortex. Its unique labeling allows for enhanced tracking in biochemical assays, aiding research in amino acid metabolism and neurological functions. -
Stable Isotope
Spermidine-d8 hydrochloride is a deuterium-labeled derivative of spermidine, functioning as a stable isotope for biochemical applications. This compound plays a critical role in enhancing cell membrane stability, elevating antioxidant enzyme activities, and improving the overall function of photosystem II (PSII). Additionally, spermidine-d8 hydrochloride has been shown to significantly reduce levels of hydrogen peroxide (H2O2) and superoxide anion (O2.-), making it valuable for research into oxidative stress and cellular signaling pathways. -
Stable Isotope
D-Xylulose-2-13C is a stable isotope-labeled form of D-xylulose, which serves as a crucial precursor in the biosynthesis of D-arabitol. Its isotopic labeling allows for precise tracking and quantification in metabolic studies. This compound is particularly valuable for researchers investigating carbohydrate metabolism and the role of pentoses in biological systems. -
Stable Isotope
Indole-15N is a stable isotope-labeled form of indole, a naturally occurring metabolite involved in various biological processes. This compound can be utilized in metabolic studies, tracer experiments, and as a precursor for the synthesis of nitrogen-containing compounds. The incorporation of the stable nitrogen isotope enables precise tracking and quantification in biological systems, making it a valuable tool for research in biochemistry, pharmacology, and molecular biology. -
Stable Isotope
alpha-D-glucose-d7 is the deuterium-labeled form of alpha-D-glucose, serving as a stable isotope. This compound functions as an endogenous metabolite, playing a crucial role in metabolic studies and tracer experiments. It is widely used in research applications involving metabolic pathways, isotopic labeling, and the analysis of glucose metabolism in various biological systems. -
Stable Isotope
D-Glucose-d1-3 is a deuterium-labeled monosaccharide that serves as a stable isotope. This compound plays a pivotal role in various metabolic processes and is essential for cellular energy production. D-Glucose is commonly utilized in research applications involving metabolic tracing and signaling pathways related to cellular metabolism and stress responses. Its unique isotopic signature allows for advanced studies in biochemical and physiological research. -
Stable Isotope
Lignoceric acid-d3 is a stable isotope-labeled derivative of Lignoceric acid, a 24-carbon saturated fatty acid (24:0) known for its role in brain development. This compound serves as a valuable tool in research focused on Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. Its unique labeling allows for precise tracking and quantification in metabolic studies and pharmaceutical research applications. -
Stable Isotope
Disodium succinate-13C2 is a stable isotope-labeled form of disodium succinate, which is the disodium salt of succinic acid. Succinic acid serves as a crucial intermediate in the tricarboxylic acid cycle, playing a significant role in energy metabolism. This reagent is particularly valuable in metabolic studies and tracer experiments, facilitating research into cellular respiration and various metabolic pathways. -
Stable Isotope
D-Fructose-4-13C is a stable isotope-labeled form of D-Fructose, a naturally occurring monosaccharide prevalent in various plants. This reagent is essential for metabolic studies and tracer experiments, enabling researchers to investigate carbohydrate metabolism in biological systems. Its distinct isotopic signature allows for precise tracking of fructose in metabolic pathways, contributing valuable insights into metabolic disorders and plant physiology research. -
Stable Isotope
Octopamine-d3 is a deuterium-labeled derivative of octopamine, serving as a stable isotope for analytical applications. It is primarily used in metabolic studies and pharmacokinetic research, allowing for detailed tracking of octopamine metabolism and distribution in biological systems. This compound facilitates the investigation of neurotransmitter regulation and its role in physiological responses. -
Stable Isotope
Menaquinone-4-d7 is a deuterium-labeled form of Menaquinone-4, also known as Vitamin K2 (MK-4). This stable isotope is utilized in biological research to track and quantify vitamin K metabolism. It serves as a valuable tool in studies related to hemostasis and the management of osteoporosis-related pain, aiding in the elucidation of its biological activities and therapeutic applications. -
Stable Isotope
Benzyl alcohol-d7 is a deuterated form of benzyl alcohol, a stable isotope used in various research applications. As an aromatic alcohol, it serves as a solvent and a reagent in synthetic chemistry. Its unique isotopic labeling allows for enhanced tracking in metabolic studies, serving as a valuable tool in pharmacokinetics and toxicology research. -
Stable Isotope
5-Methyluridine-d4 is a stable isotope-labeled form of 5-Methyluridine, an endogenous methylated nucleoside present in human biological fluids. This compound serves as a valuable tool in metabolic studies, allowing researchers to investigate nucleoside metabolism, RNA methylation patterns, and cellular signaling pathways. Its deuterium labeling provides enhanced detection capabilities in mass spectrometry, supporting various applications in pharmacokinetics and biomarker discovery. -
Stable Isotope
8-Hydroxy-2'-deoxyguanosine-15N5 is a stable isotope-labeled form of 8-Hydroxy-2'-deoxyguanosine, a significant biomarker associated with oxidative stress and the initiation of carcinogenesis. This compound is instrumental in studying DNA damage and repair mechanisms, enabling in-depth research into cancer biology and oxidative stress-related diseases. The incorporation of the 15N label enhances the detection and quantification of this important nucleoside in various biological samples, facilitating more accurate studies in molecular biology and toxicology. -
Stable Isotope
2-Naphthol-d7 is a deuterium-labeled derivative of 2-Naphthol, serving as a stable isotope. As a metabolite of naphthalene, it is produced through the enzymatic action of cytochrome P450 isozymes including CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1, and CYP 2F2. This compound is utilized in biological research for tracing metabolic pathways and studying the enzymatic activity of cytochrome P450s. Additionally, it aids in pharmacokinetic studies and provides insights into the metabolism of aromatic hydrocarbons. -
Stable Isotope
Octanoic acid-d3 is a deuterium-labeled derivative of octanoic acid, also known as caprylic acid. This stable isotope is primarily utilized in metabolic studies and isotopic tracing experiments, allowing researchers to investigate lipid metabolism and fatty acid oxidation pathways. Its unique properties make it valuable in biochemical applications, including the synthesis of esters for perfumery and the manufacturing of dyes. -
Stable Isotope
Sodium 2-hydroxybutanoate-d3 is the deuterium-labeled form of Sodium 2-hydroxybutanoate, a key endogenous metabolite involved in various metabolic pathways. This stable isotope serves as a valuable tool for metabolic tracing and studies involving deuterium incorporation in biochemical processes. Its application extends to research in metabolism, energy production, and the investigation of metabolic disorders. -
Stable Isotope
L-Thyroxine-13C6 is a stable isotope-labeled form of L-Thyroxine, a synthetic thyroid hormone essential for the investigation of hypothyroidism. It serves as a substrate for DIO enzymes, which facilitate the conversion of L-Thyroxine (T4) into the biologically active form, Triiodothyronine (T3). This reagent is valuable in metabolic studies and thyroid function research, providing insights into thyroid hormone regulation and associated disorders. -
Stable Isotope
Xanthine-15N2 is a stable isotope-labeled form of xanthine, incorporating two nitrogen-15 atoms. This compound serves as an intermediate in purine metabolism and is widely studied for its role as a mild central nervous system stimulant. Research applications include investigations into purine degradation pathways and metabolic studies involving xanthine in biological systems. -
Stable Isotope
Galactose 1-phosphate-13C potassium is a stable isotope-labeled form of galactose 1-phosphate, serving as a vital intermediate in galactose metabolism and nucleotide sugar biosynthesis. This compound is useful for metabolic studies and tracing pathways involving galactose, enabling researchers to investigate its role in cellular processes and energy production. Its isotopic label facilitates advanced analytical techniques, providing insights into metabolic flux and enzyme activity in various biological contexts. -
Stable Isotope
Xylose-2-13C is a stable isotope-labeled form of the pentose sugar D-(+)-Xylose, which serves as a substrate for xylose isomerase, yielding xylulose. This compound is instrumental in studying anaerobic ethanol fermentation pathways, facilitating the microbial conversion of xylose into fuels and valuable biochemicals. Researchers can utilize Xylose-2-13C to advance investigations into lignocellulose resource utilization and to enhance microbial fermentation processes for industrial applications. -
Stable Isotope
Tetrahydrofolic acid-d4 is a deuterium-labeled derivative of Tetrahydrofolic acid, a biologically active form of vitamin B9. This compound functions as a one-carbon donor involved in the biosynthesis of amino acids, nucleic acids, and lipids. Additionally, Tetrahydrofolic acid acts as an acceptor of free formaldehyde, yielding 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid. Its stable isotope labeling makes it suitable for metabolic studies and tracer experiments in biochemical research. -
Stable Isotope
Tristearin-d105 is a deuterated form of Tristearin, classified as a stable isotope. This triglyceride, composed of three stearic acid molecules, serves as a valuable internal standard for mass spectrometry and other analytical techniques. Tristearin-d105 is utilized in biochemical research to study lipid metabolism, energy homeostasis, and the dynamics of fat storage and mobilization in various biological systems. -
Stable Isotope
D-Fructose-d is a deuterium-labeled form of the naturally occurring monosaccharide D-Fructose. This stable isotope is utilized in metabolic studies and tracer experiments, allowing for the tracking of fructose metabolism and its biological pathways within various plant systems and organisms. D-Fructose-d is essential for researchers investigating carbohydrate metabolism and related biochemical processes. -
Stable Isotope
21-Deoxycortisol-d8 is a deuterium-labeled analog of 21-Deoxycortisol, serving as a stable isotope for analytical applications. This seminal endogenous metabolite plays a crucial role in evaluating adrenal function, particularly in the diagnosis and monitoring of congenital adrenal hyperplasia. Its isotopic labeling facilitates advanced studies in metabolic pathways and hormone analysis. -
Stable Isotope
2-Phenylacetaldehyde-d5 is a deuterated stable isotope of 2-phenylacetaldehyde, an important endogenous metabolite. This compound serves as a valuable tool in metabolic studies and tracer experiments, allowing for precise quantification and tracking of metabolic pathways in biological systems. Its utilization in research can enhance the understanding of biochemical processes and contribute to the development of new therapeutic strategies. -
Stable Isotope
D-N-Acetylgalactosamine-13C is a stable isotope-labeled form of D-N-Acetylgalactosamine, a naturally occurring metabolite. This compound serves as a valuable tool for metabolic studies, enabling researchers to trace metabolic pathways and understand galactosamine's role in various biological processes. The incorporation of the 13C label allows for precise analysis in mass spectrometry and NMR applications, facilitating advanced insights into cellular metabolism and biochemical research. -
Stable Isotope
D-Glucose-13C2 is a stable isotope-labeled form of D-Glucose, a fundamental monosaccharide. This compound plays a vital role in biological processes, serving as a primary energy source and participating in various metabolic pathways. D-Glucose-13C2 is particularly useful in isotopic labeling studies, allowing researchers to investigate metabolic dynamics, cellular metabolism, and stress responses in organisms. -
Stable Isotope
1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 is a deuterium-labeled derivative of 1-Palmitoyl-sn-glycero-3-phosphocholine, a prominent lysophosphatidylcholine. This stable isotope variant serves as a valuable tool in understanding the proinflammatory activities associated with lipid signaling. Its applications are particularly relevant in the study of atherosclerosis and other cardiovascular conditions, enabling precise tracking and analysis in metabolic and cellular research. -
Stable Isotope
Estrone-d2 is a deuterium-labeled derivative of estrone, a natural estrogenic hormone. It is primarily produced in adipose tissue and plays a crucial role in various physiological processes as an endogenous estrogen. The compound is utilized in research applications involving hormonal studies, metabolic assessments, and tracer studies to explore estrogen metabolism and distribution in biological systems. -
Stable Isotope
Liothyronine-13C9,15N is a stable isotope-labeled derivative of Liothyronine, the active form of thyroid hormone. It functions as an agonist of thyroid hormone receptors TRα and TRβ, exhibiting high potency with Kis of 2.33 nM for both human TRα and TRβ. This compound is valuable for research applications involving thyroid function studies, metabolic regulation, and endocrine signaling pathways. -
Stable Isotope
α-Tocopherol-d6 acetate is a deuterium-labeled derivative of D-α-Tocopherol acetate, functioning as a stable isotope. This compound can be hydrolyzed to release d-alpha-tocopherol, commonly known as Vitamin E, which is then absorbed in the small intestine. α-Tocopherol-d6 acetate is utilized in metabolic studies and analytical research to track tocopherol metabolism and bioavailability in biological systems. -
Stable Isotope
5-Hydroxytryptophol-d4 is a deuterium-labeled derivative of 5-Hydroxytryptophol, a significant metabolite of serotonin in mammals. This stable isotope serves as a valuable marker for studying acute alcohol consumption and its effects on serotonin metabolism. Its applications extend to biochemical research, enabling precise tracking of metabolic pathways and the investigation of alcohol's impact on serotonin-related processes. -
Stable Isotope
Monobenzyl phthalate-d4 is a deuterium-labeled variant of Monobenzyl phthalate, a compound associated with the metabolism of phthalates, such as diethylhexyl phthalate (DEHP). This stable isotope serves as a valuable internal standard in analytical chemistry and toxicology studies. It is particularly useful in investigations of phthalate exposure and metabolic pathways, allowing for precise quantification and improved detection of urinary metabolites. -
Stable Isotope
D-Glucose-d1-2 is a deuterium-labeled analog of D-Glucose, serving as a stable isotope for metabolic studies. As a monosaccharide, D-Glucose plays a vital role in cellular metabolism, functioning as a key energy source and signaling molecule. This reagent is widely utilized in research applications, including metabolic flux analysis, tracer studies, and investigations into biotic and abiotic stress responses in various biological systems. -
Stable Isotope
Pentadecanoic acid-d2 is a deuterium-labeled derivative of pentadecanoic acid, a saturated fatty acid characterized by a 15-carbon atom backbone. This stable isotope is utilized in metabolic studies and tracer experiments, enabling precise quantification and tracking of fatty acid metabolism in biological systems. Its application is valuable in research areas such as lipid biochemistry and nutritional studies, facilitating insights into fatty acid absorption and metabolism. -
Stable Isotope
2'-Deoxyguanosine-13C10,15N5 monohydrate is a stable isotope-labeled form of 2'-Deoxyguanosine, incorporating carbon-13 and nitrogen-15. This compound serves as a valuable internal standard in mass spectrometry and NMR studies, enabling precise tracking of metabolic pathways and cellular processes. Its use is pivotal in research areas such as nucleotide metabolism, genomic studies, and biomarker identification. -
Stable Isotope
Fumaric acid-13C2,d2 is a stable isotope-labeled form of fumaric acid, incorporating deuterium and carbon-13. This compound is significant in the study of fumarase deficiency and is recognized as an oncometabolite, which plays a role in various cancer-related metabolic pathways. It is valuable for research applications involving metabolic tracing, cancer metabolism studies, and the investigation of cellular responses to oncogenic stress.
