Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
L-Pyroglutamic acid-13C5 is a stable isotope-labeled form of L-Pyroglutamic acid that serves as a key metabolite in glutathione metabolism. The levo-isomer, L-Pyroglutamic acid is biologically active in humans and is utilized as a biomarker for systemic lupus erythematosus (SLE). This reagent is ideal for applications in metabolic studies and isotopic tracing experiments, providing insights into biochemical pathways and disease mechanisms. -
Stable Isotope
Oxalic Acid-d2 is the deuterium-labeled derivative of oxalic acid, a potent dicarboxylic acid found in a variety of plants and vegetables. This stable isotope is primarily employed as an analytical reagent in studies requiring precise isotope labeling and as a general reducing agent in various chemical reactions. Its applications extend to biochemical research, metabolomics, and isotopic tracing studies. -
Stable Isotope
L-Tyrosine-17O is a 17O-labeled form of the non-essential amino acid L-Tyrosine. This stable isotope serves as a valuable tool in metabolic studies, particularly for tracing metabolic pathways and assessing the activity of enzymes such as citrate synthase in the posterior cortex. Its use is essential in various biochemical and pharmacological research applications, enabling enhanced understanding of amino acid metabolism and related physiological processes. -
Stable Isotope
D-Mannose-13C is a stable isotope-labeled form of D-Mannose, a monosaccharide critical for various metabolic processes. This compound is integral for the glycosylation of specific proteins, influencing cell signaling and recognition mechanisms. D-Mannose-13C can be utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and cell surface interactions in biological research. -
Stable Isotope
Estrone-d2-1 is a deuterium-labeled analog of estrone, a natural estrogenic hormone. This stable isotope serves as a valuable tool for quantitative studies in endocrinology and metabolic research. Estrone plays a crucial role in various biological processes and is primarily produced in adipose tissue through the aromatization of androstenedione. The use of Estrone-d2-1 facilitates precise tracing in pharmacokinetic studies, hormone signaling research, and the investigation of estrogen-related diseases. -
Stable Isotope
D-Fructose-13C-1 is a stable isotope-labeled form of D-Fructose, a naturally occurring monosaccharide prevalent in various plants. This stable isotope variant is utilized in metabolic studies, enabling researchers to trace carbohydrate metabolism and flux in biological systems with precision. Its application in positron emission tomography (PET) imaging and other analytical techniques provides valuable insights into energy metabolism and cellular functions. -
Stable Isotope
D-Xylulose-1-13C is a stable isotope-labeled form of D-Xylulose, featuring carbon-13 for precise tracking in metabolic studies. As a key precursor in the biosynthesis of D-arabinose, its use is significant in research related to carbohydrate metabolism and glycoprotein synthesis. It aids in elucidating metabolic pathways and understanding the role of sugars in cellular processes. -
Stable Isotope
Glycerol-13C is a stable isotope-labeled form of glycerol, primarily utilized in biochemical research and analytical applications. Its incorporation into samples enhances the accuracy of NMR spectroscopy and other analytical techniques. Glycerol-13C serves as a valuable tool in the preparation of samples for polyacrylamide gel electrophoresis, facilitating improved resolution and characterization of biomolecules. -
Stable Isotope
DHEA-d5 (Dehydroepiandrosterone-d5) is a stable isotope-labeled form of DHEA, one of the most prevalent steroid hormones. It plays a crucial role in various signaling pathways by binding to specific membrane receptors and serving as a precursor for androgens and estrogens, including 7α and 7β DHEA, as well as their respective derivatives. DHEA-d5 is valuable for research applications in hormone metabolism, steroidogenesis studies, and tracking endogenous hormone levels in biological samples. -
Stable Isotope
Dihydrouracil-13C4,15N2 is a stable isotope-labeled form of Dihydrouracil, incorporating both 13C and 15N atoms. Dihydrouracil, a metabolite of Uracil, serves as an important marker for the identification of dihydropyrimidine dehydrogenase (DPD) deficiency. Its unique isotopic signature enhances the accuracy of metabolic studies, making it valuable in pharmacogenomics and cancer research applications. -
Stable Isotope
L-Alanine-13C2,15N is a stable isotope-labeled form of the non-essential amino acid L-Alanine, featuring two carbon-13 and one nitrogen-15 isotopes. This compound participates in metabolic pathways, including sugar and acid metabolism, and is crucial for enhancing immunity and providing energy to muscle tissue and the central nervous system. L-Alanine-13C2,15N is employed in isotopic labeling studies, metabolic flux analysis, and other research applications involving amino acid metabolism. -
Stable Isotope
Pyridoxine-d5 is a deuterium-labeled derivative of pyridoxine, serving as a stable isotope for research applications. This compound exhibits antioxidant properties in cellular models of Alzheimer's disease, primarily through the activation of the Nrf-2/HO-1 signaling pathway. Pyridoxine-d5 is valuable for studies investigating the metabolic and therapeutic roles of vitamin B6 in neuronal health and oxidative stress. -
Stable Isotope
L-Aspartic acid-1,4-13C2 is a stable isotope-labeled form of L-Aspartic acid, which is a naturally occurring amino acid capable of crossing the blood-brain barrier. This compound plays a crucial role in metabolic studies and is often utilized in the development of prodrugs targeting colon and cecal tissues. Additionally, L-Aspartic acid-1,4-13C2 is valuable in research related to inflammatory conditions, providing insights into amino acid metabolism and neurotransmitter functions. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-d31 is a deuterium-labeled variant of propane-1,2,3-triyl tripalmitate, an endogenous metabolite involved in lipid metabolism. This stable isotope is utilized in tracer studies to investigate metabolic pathways and lipid dynamics in various biological systems. Its incorporation of deuterium allows for enhanced detection and quantification in analytical studies, making it valuable for research in metabolic profiling and related fields. -
Stable Isotope
Progesterone-13C3 is a stable isotope-labeled form of progesterone. As a steroid hormone, progesterone plays a key role in regulating the menstrual cycle and maintaining pregnancy. This isotope can be utilized in various research applications, including metabolic studies and the investigation of hormone dynamics in biological systems. It serves as a valuable tool for elucidating the pharmacokinetics and biological effects of progesterone. -
Stable Isotope
Glycerol-d3 is a deuterium-labeled form of glycerol, serving as a stable isotope for various applications. It is commonly utilized in sample preparation and plays a critical role in gel formation for polyacrylamide gel electrophoresis. Its incorporation of deuterium enhances the accuracy of quantitative analyses and provides insights into biophysical properties within biochemical research. -
Stable Isotope
D-Glucose-18O is a stable isotope of D-Glucose, a fundamental monosaccharide involved in various metabolic processes. This compound plays a crucial role in carbohydrate metabolism and cellular signaling. D-Glucose-18O can be utilized in research applications such as metabolic studies, tracer experiments, and to investigate glucose utilization and turnover in biological systems. -
Stable Isotope
Uracil-15N2 is a stable isotope-labeled form of uracil, a naturally occurring pyrimidine derivative and a key nucleobase in RNA. This labeled compound is utilized in molecular biology and biochemical research to study RNA metabolism, nucleobase incorporation, and nucleic acid interactions. Its unique isotopic signature allows for precise tracking in various applications, including metabolic studies and tracer experiments. -
Stable Isotope
L-2-Aminobutyric acid-d6 is a deuterated analog of L-2-Aminobutyric acid, a non-proteinogenic amino acid found in human tissues and body fluids. This compound participates in metabolic pathways as a result of the transamination of oxobutyric acid. L-2-Aminobutyric acid-d6 serves as a valuable stable isotope for research applications, particularly in the development of anticonvulsant and anti-tuberculosis agents, as well as acting as a key intermediate in the chemical and pharmaceutical industries. -
Stable Isotope
D-Alanine-d7 is a deuterium-labeled form of D-Alanine, functioning primarily as a stable isotope. It exhibits low agonist activity at Glycine Receptors (GlyR) with an EC50 value of 9 mM, which allows for the study of these receptors in various biological contexts. This compound is valuable in research applications involving metabolic tracing and the investigation of amino acid metabolism dynamics. -
Stable Isotope
Lysophosphatidylcholine 18:2-d9 is a deuterated form of lysophosphatidylcholine 18:2, recognized for its role as a stable isotope tracer. This lysophospholipid has been investigated as a potential biomarker for insulin resistance, particularly in the context of polycystic ovary syndrome. It aids in metabolic research by providing insights into lipid metabolism and associated disorders. -
Stable Isotope
Benzyl alcohol-13C6 is a stable isotope-labeled form of benzyl alcohol, featuring six carbon-13 isotopes. This compound is primarily utilized as a tracer in metabolic studies and various analytical applications. It serves as an internal standard in quantitative mass spectrometry, enabling precise determination of molecular pathways and metabolism involving aromatic alcohols. Benzyl alcohol-13C6 is essential for researchers investigating isotopic labeling and tracing in biochemical processes. -
Stable Isotope
L-Alanine-3-13C is a stable isotope-labeled form of the non-essential amino acid L-Alanine. It plays a crucial role in sugar and acid metabolism, contributes to immune enhancement, and supplies energy to muscle tissues, the brain, and the central nervous system. This reagent is useful in metabolic studies and tracer experiments, enabling researchers to investigate metabolic pathways and amino acid utilization. -
Stable Isotope
Myristic acid-13C3 is a stable isotope-labeled form of myristic acid, a saturated 14-carbon fatty acid commonly found in various animal and vegetable fats, including butterfat, coconut oil, palm oil, and nutmeg oil. This compound serves as a valuable tool in metabolic studies and isotopic labeling experiments, aiding in the investigation of lipid metabolism and fatty acid biosynthesis. Its use facilitates the tracing of metabolic pathways and the quantification of lipid concentrations in biological systems. -
Stable Isotope
L-Cysteine-d2 is a deuterium-labeled form of the conditionally essential amino acid L-Cysteine. This compound serves as a precursor for biologically active molecules, including hydrogen sulfide (H2S), glutathione, and taurine. L-Cysteine has been shown to suppress ghrelin levels, thereby reducing appetite in both rodent models and human studies. It is valuable in metabolic research and studies examining amino acid functions in physiological processes. -
Stable Isotope
15(S)-HETE-d8 is a deuterated derivative of 15(S)-HETE, serving as a stable isotope labeled compound. This reagent is primarily utilized in quantitative analysis and metabolic studies, allowing for precise tracking of lipid metabolism and signaling pathways in biological systems. It aids in the investigation of the physiological roles of 15-hydroxyeicosatetraenoic acid in inflammation and other cellular processes. -
Stable Isotope
D-Galactose-d2-1 is a stable isotope-labeled form of D-Galactose, a naturally occurring aldohexose and C-4 epimer of glucose. This reagent serves as a valuable tool in metabolic studies and isotopic labeling experiments. It allows for precise tracking of galactose metabolism in biochemical and physiological contexts, facilitating research in cellular metabolism, glycosylation pathways, and carbohydrate dynamics. -
Stable Isotope
4-Ethylphenol-d5 is the deuterated form of 4-Ethylphenol, a volatile phenolic compound primarily associated with off-flavors in wine. The compound is known to be synthesized by intestinal microbiota, particularly Lactobacillus plantarum, which further metabolizes it to 4-ethylphenyl sulfate. This stable isotope serves as an essential tool for tracing studies and analyzing metabolic processes in microbiome research and food science applications. -
Stable Isotope
Thiamine monochloride-13C4 hydrochloride is a stable isotope-labeled form of thiamine hydrochloride, which serves as a crucial cofactor for numerous central metabolic enzymes. This compound plays a significant role in carbohydrate metabolism and energy production, making it essential for various biological processes. It is widely utilized in metabolic studies and isotopic labeling experiments to trace metabolic pathways and investigate thiamine-related functions in cellular systems. -
Stable Isotope
L-2-Aminobutyric acid-d3 is a deuterated form of L-2-Aminobutyric acid, a non-proteinogenic amino acid found in various human tissues and bodily fluids. It is synthesized through the transamination of oxobutyric acid and is notable for its role as a precursor in the production of anticonvulsant and anti-tuberculosis compounds. This stable isotope is valuable for applications in chemical and pharmaceutical research, particularly in studies aiming to trace metabolic pathways and assess biological activity. -
Stable Isotope
Glycocholic acid-d5 is a stable isotope-labeled form of glycocholic acid, a bile acid known for its anticancer properties. It targets both pump resistance-related and non-pump resistance-related pathways, making it a valuable tool for cancer research. This reagent is suitable for studies involving metabolic profiling, pharmacokinetics, and mechanistic investigations of bile acid signaling in various biological systems. -
Stable Isotope
Cholestenone-13C2 is a stable isotope-labeled derivative of Cholestenone (4-Cholesten-3-one), which serves as an intermediate in cholesterol oxidation, predominantly in the liver. This compound is critical for studies investigating membrane dynamics, particularly the processes of cholesterol flip-flop and efflux. Its application extends to research on cellular cholesterol metabolism and potential long-term functional effects on cellular systems. -
Stable Isotope
Pyruvic acid-1-13C-2 sodium is a stable isotope-labeled form of pyruvic acid, functioning primarily as a metabolic intermediate in the pathways of carbohydrate, protein, and fat metabolism. This reagent is valuable for studies involving metabolic tracing and flux analysis, allowing researchers to investigate metabolic pathways and energy production in various biological systems. Its stable isotope labeling enables precise quantification and tracking during metabolic experiments. -
Stable Isotope
Benzo[a]pyrene-d12 is the deuterium-labeled derivative of Benzo[a]pyrene, a known carcinogen with specific lung tumorigenic properties in animal models. This stable isotope is utilized in various research applications, particularly in chemoprevention studies, to trace metabolic pathways and assess carcinogenic mechanisms. Its use enhances the understanding of cancer biology and the development of potential therapeutic strategies. -
Stable Isotope
Ethylene glycol-13C2 is a stable isotope-labeled form of ethylene glycol, incorporating two carbon-13 atoms. This compound is utilized in metabolic tracing studies and as a reference standard in various analytical techniques, including nuclear magnetic resonance (NMR) spectroscopy. Its application extends to investigations in biochemistry and environmental science, facilitating the understanding of metabolic pathways and the fate of chemicals in biological systems. -
Stable Isotope
Xylose-1-13C is a stable isotope-labeled form of xylose, specifically incorporating the carbon-13 isotope at position one. This reagent is valuable for metabolic studies, enabling precise tracking and quantification of xylose metabolism in biological systems. Its applications extend to research on carbohydrate metabolism, glycoprotein synthesis, and other biochemical pathways involving xylose and related sugars. -
Stable Isotope
β-Alanine-13C3,15N is a stable isotope-labeled derivative of β-Alanine, incorporating both 13C and 15N isotopes. As a non-essential amino acid, β-Alanine plays a crucial role in the synthesis of carnosine, an important intracellular buffer. This isotopically labeled compound is valuable for metabolic studies and tracer experiments, providing insights into amino acid metabolism and the dynamics of carnosine formation in biological systems. -
Stable Isotope
Glycodeoxycholic acid-d6 is a deuterium-labeled derivative of Glycodeoxycholic Acid, an endogenous bile acid metabolite. This stable isotope is primarily used in metabolic studies and isotopic tracing applications within biological systems. Its unique labeling allows for enhanced accuracy in the analysis of metabolic pathways and dynamics in research involving bile acids and related metabolism. -
Stable Isotope
Carbamazepine 10,11 epoxide-d10 is a deuterium-labeled derivative of Carbamazepine 10,11 epoxide, a compound primarily known for its role as an anticonvulsant agent. This stable isotope is utilized in pharmacokinetic studies to investigate the metabolism and bioavailability of Carbamazepine in biological systems. It serves as a valuable tool for researchers exploring drug interactions and metabolic pathways involving anticonvulsants. -
Stable Isotope
Cinnamic acid-13C3, a stable isotope-labeled derivative of cinnamic acid, is primarily utilized in metabolic studies and tracer experiments. This compound demonstrates potential in cancer research, exhibiting IC50 values between 1 to 4.5 mM against various cancer cell lines, including glioblastoma, melanoma, prostate, and lung carcinoma. Its application in tracing biochemical pathways makes it valuable for understanding metabolic processes in cancer biology. -
Stable Isotope
L-Leucine-d2 is a deuterium-labeled form of the essential branched-chain amino acid L-Leucine. This stable isotope enhances studies involving metabolic processes, particularly in research related to the mTOR signaling pathway, which regulates cell growth and protein synthesis. L-Leucine-d2 is also valuable in tracer studies and quantitative analysis in metabolic and nutritional research. -
Stable Isotope
SAH-13C10 is a stable isotope labeled derivative of S-Adenosylhomocysteine (SAH). As an important amino acid derivative, SAH plays a crucial role as a modulator in various metabolic pathways and serves as an intermediate in the synthesis of cysteine and adenosine. It functions as an inhibitor of the METTL3-METTL14 heterodimer complex, demonstrating an IC50 of 0.9 μM, making it valuable for research in epitranscriptomics and cellular metabolism studies. -
Stable Isotope
Cinnamoylglycine-d2 is the deuterium-labeled form of cinnamoylglycine, a glycine conjugate of cinnamic acid and a relevant urinary metabolite in humans. This stable isotope serves as a valuable tool for research examining colonization resistance, particularly in the context of antibiotic treatment. Its application in biomarker studies aids in understanding the effects of antibiotics on gut microbiota and metabolic processes. -
Stable Isotope
β-Alanine-15N is a stable isotope-labeled form of the non-essential amino acid β-Alanine. This compound plays a crucial role in the biosynthesis of carnosine, an important intracellular buffer that helps maintain pH homeostasis. β-Alanine-15N is utilized in metabolic studies and isotopic tracing experiments to investigate amino acid metabolism and the physiological functions of carnosine in various biological systems. -
Stable Isotope
Sucralose-d6 is a deuterium-labeled derivative of Sucralose, a widely used non-nutritive artificial sweetener. This stable isotope is utilized in metabolic studies to investigate the physiological effects of sweeteners, including their role in appetite regulation. Research indicates that Sucralose can trigger a conserved neural fasting response, resulting in an appetite-stimulating effect in rodent models. -
Stable Isotope
DL-Alanine-13C-3 is a stable isotope-labeled form of DL-alanine, an important amino acid characterized by its racemic nature of L- and D-alanine. This compound serves as a reducing and capping agent in the synthesis of nanoparticles, particularly in conjunction with silver nitrate. DL-alanine-13C-3 is valuable for research into transition metal chelation, including interactions with Cu(II), Zn(II), and Cd(II). Additionally, it plays a crucial role in the glucose-alanine cycle, facilitating metabolic processes between tissues and the liver. -
Stable Isotope
Octanoic acid-13C is a stable isotope-labeled form of octanoic acid, also known as caprylic acid. This compound serves as an important tracer in metabolic studies and isotope-labeling experiments due to its unique carbon-13 signature. Octanoic acid is widely utilized in the production of esters for perfumery and in dye manufacturing, making it a valuable reagent for various chemical research applications. -
Stable Isotope
DL-Tryptophan-d8 is a deuterium-labeled analogue of DL-Tryptophan, an endogenous metabolite that serves as a precursor for neurotransmitters such as serotonin. This stable isotope is valuable in metabolic studies and tracer experiments, allowing for precise tracking of tryptophan metabolism and its derivatives in biological systems. DL-Tryptophan-d8 is essential for research applications involving isotopic labeling, providing insights into metabolic pathways and biochemical mechanisms. -
Stable Isotope
N-Acetyl-D-glucosamine-13C2,15N is a stable isotope-labeled analogue of N-Acetyl-D-glucosamine, incorporating two carbon-13 atoms and one nitrogen-15 atom. This compound serves as a valuable tool for metabolic studies and tracer applications in carbohydrate metabolism. Its use in biochemistry and molecular biology can provide insights into glycosylation processes and cellular function, making it essential for research involving glycosaminoglycans and related biomolecules. -
Stable Isotope
2-Methylcitric acid-d3 trisodium is a deuterium-labeled form of 2-Methylcitric acid, serving as a stable isotope for analytical applications. This compound is utilized in metabolic studies and tracer experiments to investigate metabolic pathways involving citric acid metabolism. Its stable isotopic nature provides enhanced sensitivity and accuracy in detecting metabolic products in biological samples.
