Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Uracil-15N2 is a stable isotope-labeled form of uracil, a naturally occurring pyrimidine derivative and a key nucleobase in RNA. This labeled compound is utilized in molecular biology and biochemical research to study RNA metabolism, nucleobase incorporation, and nucleic acid interactions. Its unique isotopic signature allows for precise tracking in various applications, including metabolic studies and tracer experiments. -
Stable Isotope
L-2-Aminobutyric acid-d6 is a deuterated analog of L-2-Aminobutyric acid, a non-proteinogenic amino acid found in human tissues and body fluids. This compound participates in metabolic pathways as a result of the transamination of oxobutyric acid. L-2-Aminobutyric acid-d6 serves as a valuable stable isotope for research applications, particularly in the development of anticonvulsant and anti-tuberculosis agents, as well as acting as a key intermediate in the chemical and pharmaceutical industries. -
Stable Isotope
D-Alanine-d7 is a deuterium-labeled form of D-Alanine, functioning primarily as a stable isotope. It exhibits low agonist activity at Glycine Receptors (GlyR) with an EC50 value of 9 mM, which allows for the study of these receptors in various biological contexts. This compound is valuable in research applications involving metabolic tracing and the investigation of amino acid metabolism dynamics. -
Stable Isotope
Lysophosphatidylcholine 18:2-d9 is a deuterated form of lysophosphatidylcholine 18:2, recognized for its role as a stable isotope tracer. This lysophospholipid has been investigated as a potential biomarker for insulin resistance, particularly in the context of polycystic ovary syndrome. It aids in metabolic research by providing insights into lipid metabolism and associated disorders. -
Stable Isotope
Benzyl alcohol-13C6 is a stable isotope-labeled form of benzyl alcohol, featuring six carbon-13 isotopes. This compound is primarily utilized as a tracer in metabolic studies and various analytical applications. It serves as an internal standard in quantitative mass spectrometry, enabling precise determination of molecular pathways and metabolism involving aromatic alcohols. Benzyl alcohol-13C6 is essential for researchers investigating isotopic labeling and tracing in biochemical processes. -
Stable Isotope
L-Alanine-3-13C is a stable isotope-labeled form of the non-essential amino acid L-Alanine. It plays a crucial role in sugar and acid metabolism, contributes to immune enhancement, and supplies energy to muscle tissues, the brain, and the central nervous system. This reagent is useful in metabolic studies and tracer experiments, enabling researchers to investigate metabolic pathways and amino acid utilization. -
Stable Isotope
Myristic acid-13C3 is a stable isotope-labeled form of myristic acid, a saturated 14-carbon fatty acid commonly found in various animal and vegetable fats, including butterfat, coconut oil, palm oil, and nutmeg oil. This compound serves as a valuable tool in metabolic studies and isotopic labeling experiments, aiding in the investigation of lipid metabolism and fatty acid biosynthesis. Its use facilitates the tracing of metabolic pathways and the quantification of lipid concentrations in biological systems. -
Stable Isotope
L-Cysteine-d2 is a deuterium-labeled form of the conditionally essential amino acid L-Cysteine. This compound serves as a precursor for biologically active molecules, including hydrogen sulfide (H2S), glutathione, and taurine. L-Cysteine has been shown to suppress ghrelin levels, thereby reducing appetite in both rodent models and human studies. It is valuable in metabolic research and studies examining amino acid functions in physiological processes. -
Stable Isotope
15(S)-HETE-d8 is a deuterated derivative of 15(S)-HETE, serving as a stable isotope labeled compound. This reagent is primarily utilized in quantitative analysis and metabolic studies, allowing for precise tracking of lipid metabolism and signaling pathways in biological systems. It aids in the investigation of the physiological roles of 15-hydroxyeicosatetraenoic acid in inflammation and other cellular processes. -
Stable Isotope
D-Galactose-d2-1 is a stable isotope-labeled form of D-Galactose, a naturally occurring aldohexose and C-4 epimer of glucose. This reagent serves as a valuable tool in metabolic studies and isotopic labeling experiments. It allows for precise tracking of galactose metabolism in biochemical and physiological contexts, facilitating research in cellular metabolism, glycosylation pathways, and carbohydrate dynamics. -
Stable Isotope
4-Ethylphenol-d5 is the deuterated form of 4-Ethylphenol, a volatile phenolic compound primarily associated with off-flavors in wine. The compound is known to be synthesized by intestinal microbiota, particularly Lactobacillus plantarum, which further metabolizes it to 4-ethylphenyl sulfate. This stable isotope serves as an essential tool for tracing studies and analyzing metabolic processes in microbiome research and food science applications. -
Stable Isotope
Thiamine monochloride-13C4 hydrochloride is a stable isotope-labeled form of thiamine hydrochloride, which serves as a crucial cofactor for numerous central metabolic enzymes. This compound plays a significant role in carbohydrate metabolism and energy production, making it essential for various biological processes. It is widely utilized in metabolic studies and isotopic labeling experiments to trace metabolic pathways and investigate thiamine-related functions in cellular systems. -
Stable Isotope
L-2-Aminobutyric acid-d3 is a deuterated form of L-2-Aminobutyric acid, a non-proteinogenic amino acid found in various human tissues and bodily fluids. It is synthesized through the transamination of oxobutyric acid and is notable for its role as a precursor in the production of anticonvulsant and anti-tuberculosis compounds. This stable isotope is valuable for applications in chemical and pharmaceutical research, particularly in studies aiming to trace metabolic pathways and assess biological activity. -
Stable Isotope
Glycocholic acid-d5 is a stable isotope-labeled form of glycocholic acid, a bile acid known for its anticancer properties. It targets both pump resistance-related and non-pump resistance-related pathways, making it a valuable tool for cancer research. This reagent is suitable for studies involving metabolic profiling, pharmacokinetics, and mechanistic investigations of bile acid signaling in various biological systems. -
Stable Isotope
Cholestenone-13C2 is a stable isotope-labeled derivative of Cholestenone (4-Cholesten-3-one), which serves as an intermediate in cholesterol oxidation, predominantly in the liver. This compound is critical for studies investigating membrane dynamics, particularly the processes of cholesterol flip-flop and efflux. Its application extends to research on cellular cholesterol metabolism and potential long-term functional effects on cellular systems. -
Stable Isotope
Pyruvic acid-1-13C-2 sodium is a stable isotope-labeled form of pyruvic acid, functioning primarily as a metabolic intermediate in the pathways of carbohydrate, protein, and fat metabolism. This reagent is valuable for studies involving metabolic tracing and flux analysis, allowing researchers to investigate metabolic pathways and energy production in various biological systems. Its stable isotope labeling enables precise quantification and tracking during metabolic experiments. -
Stable Isotope
Benzo[a]pyrene-d12 is the deuterium-labeled derivative of Benzo[a]pyrene, a known carcinogen with specific lung tumorigenic properties in animal models. This stable isotope is utilized in various research applications, particularly in chemoprevention studies, to trace metabolic pathways and assess carcinogenic mechanisms. Its use enhances the understanding of cancer biology and the development of potential therapeutic strategies. -
Stable Isotope
Ethylene glycol-13C2 is a stable isotope-labeled form of ethylene glycol, incorporating two carbon-13 atoms. This compound is utilized in metabolic tracing studies and as a reference standard in various analytical techniques, including nuclear magnetic resonance (NMR) spectroscopy. Its application extends to investigations in biochemistry and environmental science, facilitating the understanding of metabolic pathways and the fate of chemicals in biological systems. -
Stable Isotope
Xylose-1-13C is a stable isotope-labeled form of xylose, specifically incorporating the carbon-13 isotope at position one. This reagent is valuable for metabolic studies, enabling precise tracking and quantification of xylose metabolism in biological systems. Its applications extend to research on carbohydrate metabolism, glycoprotein synthesis, and other biochemical pathways involving xylose and related sugars. -
Stable Isotope
β-Alanine-13C3,15N is a stable isotope-labeled derivative of β-Alanine, incorporating both 13C and 15N isotopes. As a non-essential amino acid, β-Alanine plays a crucial role in the synthesis of carnosine, an important intracellular buffer. This isotopically labeled compound is valuable for metabolic studies and tracer experiments, providing insights into amino acid metabolism and the dynamics of carnosine formation in biological systems. -
Stable Isotope
Glycodeoxycholic acid-d6 is a deuterium-labeled derivative of Glycodeoxycholic Acid, an endogenous bile acid metabolite. This stable isotope is primarily used in metabolic studies and isotopic tracing applications within biological systems. Its unique labeling allows for enhanced accuracy in the analysis of metabolic pathways and dynamics in research involving bile acids and related metabolism. -
Stable Isotope
Carbamazepine 10,11 epoxide-d10 is a deuterium-labeled derivative of Carbamazepine 10,11 epoxide, a compound primarily known for its role as an anticonvulsant agent. This stable isotope is utilized in pharmacokinetic studies to investigate the metabolism and bioavailability of Carbamazepine in biological systems. It serves as a valuable tool for researchers exploring drug interactions and metabolic pathways involving anticonvulsants. -
Stable Isotope
Cinnamic acid-13C3, a stable isotope-labeled derivative of cinnamic acid, is primarily utilized in metabolic studies and tracer experiments. This compound demonstrates potential in cancer research, exhibiting IC50 values between 1 to 4.5 mM against various cancer cell lines, including glioblastoma, melanoma, prostate, and lung carcinoma. Its application in tracing biochemical pathways makes it valuable for understanding metabolic processes in cancer biology. -
Stable Isotope
L-Leucine-d2 is a deuterium-labeled form of the essential branched-chain amino acid L-Leucine. This stable isotope enhances studies involving metabolic processes, particularly in research related to the mTOR signaling pathway, which regulates cell growth and protein synthesis. L-Leucine-d2 is also valuable in tracer studies and quantitative analysis in metabolic and nutritional research. -
Stable Isotope
SAH-13C10 is a stable isotope labeled derivative of S-Adenosylhomocysteine (SAH). As an important amino acid derivative, SAH plays a crucial role as a modulator in various metabolic pathways and serves as an intermediate in the synthesis of cysteine and adenosine. It functions as an inhibitor of the METTL3-METTL14 heterodimer complex, demonstrating an IC50 of 0.9 μM, making it valuable for research in epitranscriptomics and cellular metabolism studies. -
Stable Isotope
Cinnamoylglycine-d2 is the deuterium-labeled form of cinnamoylglycine, a glycine conjugate of cinnamic acid and a relevant urinary metabolite in humans. This stable isotope serves as a valuable tool for research examining colonization resistance, particularly in the context of antibiotic treatment. Its application in biomarker studies aids in understanding the effects of antibiotics on gut microbiota and metabolic processes. -
Stable Isotope
β-Alanine-15N is a stable isotope-labeled form of the non-essential amino acid β-Alanine. This compound plays a crucial role in the biosynthesis of carnosine, an important intracellular buffer that helps maintain pH homeostasis. β-Alanine-15N is utilized in metabolic studies and isotopic tracing experiments to investigate amino acid metabolism and the physiological functions of carnosine in various biological systems. -
Stable Isotope
Sucralose-d6 is a deuterium-labeled derivative of Sucralose, a widely used non-nutritive artificial sweetener. This stable isotope is utilized in metabolic studies to investigate the physiological effects of sweeteners, including their role in appetite regulation. Research indicates that Sucralose can trigger a conserved neural fasting response, resulting in an appetite-stimulating effect in rodent models. -
Stable Isotope
DL-Alanine-13C-3 is a stable isotope-labeled form of DL-alanine, an important amino acid characterized by its racemic nature of L- and D-alanine. This compound serves as a reducing and capping agent in the synthesis of nanoparticles, particularly in conjunction with silver nitrate. DL-alanine-13C-3 is valuable for research into transition metal chelation, including interactions with Cu(II), Zn(II), and Cd(II). Additionally, it plays a crucial role in the glucose-alanine cycle, facilitating metabolic processes between tissues and the liver. -
Stable Isotope
Octanoic acid-13C is a stable isotope-labeled form of octanoic acid, also known as caprylic acid. This compound serves as an important tracer in metabolic studies and isotope-labeling experiments due to its unique carbon-13 signature. Octanoic acid is widely utilized in the production of esters for perfumery and in dye manufacturing, making it a valuable reagent for various chemical research applications. -
Stable Isotope
DL-Tryptophan-d8 is a deuterium-labeled analogue of DL-Tryptophan, an endogenous metabolite that serves as a precursor for neurotransmitters such as serotonin. This stable isotope is valuable in metabolic studies and tracer experiments, allowing for precise tracking of tryptophan metabolism and its derivatives in biological systems. DL-Tryptophan-d8 is essential for research applications involving isotopic labeling, providing insights into metabolic pathways and biochemical mechanisms. -
Stable Isotope
N-Acetyl-D-glucosamine-13C2,15N is a stable isotope-labeled analogue of N-Acetyl-D-glucosamine, incorporating two carbon-13 atoms and one nitrogen-15 atom. This compound serves as a valuable tool for metabolic studies and tracer applications in carbohydrate metabolism. Its use in biochemistry and molecular biology can provide insights into glycosylation processes and cellular function, making it essential for research involving glycosaminoglycans and related biomolecules. -
Stable Isotope
2-Methylcitric acid-d3 trisodium is a deuterium-labeled form of 2-Methylcitric acid, serving as a stable isotope for analytical applications. This compound is utilized in metabolic studies and tracer experiments to investigate metabolic pathways involving citric acid metabolism. Its stable isotopic nature provides enhanced sensitivity and accuracy in detecting metabolic products in biological samples. -
Stable Isotope
2'-Deoxycytidine-13C9,15N3 is a stable isotope-labeled form of the nucleoside 2'-deoxycytidine, featuring carbon-13 and nitrogen-15 isotopes. It serves as a valuable tool in metabolic studies and tracing experiments due to its ability to participate in nucleic acid metabolism. This reagent can also inhibit the biological effects of bromodeoxyuridine (BrdU), making it useful in studies pertaining to DNA synthesis and cellular proliferation. Researchers can employ 2'-Deoxycytidine-13C9,15N3 in various biological assays to explore cellular processes involving nucleotides and their derivatives. -
Stable Isotope
L-Leucine-18O2 is the stable isotope-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) known to activate the mTOR signaling pathway. This compound is utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and protein synthesis. Its stable isotope labeling enables precise quantification and tracking of L-Leucine in biological systems, making it valuable for research in nutrition, exercise physiology, and cellular signaling. -
Stable Isotope
N-Acetylglycine-d2 is a deuterated isotope of N-Acetylglycine, primarily utilized as a stable isotope for scientific research. This compound serves as a flavor enhancer and demonstrates sensory properties similar to monosodium glutamate (MSG), making it valuable in food science studies. Its applications extend to metabolic studies, tracing synthesis pathways, and flavor profile analysis in nutritional research. -
Stable Isotope
Homogentisic acid-13C6 is a stable isotope-labeled form of homogentisic acid, a phenolic acid metabolite. This compound is significant in the diagnosis of alkaptonuria, a rare metabolic disorder characterized by the accumulation of homogentisic acid in urine and serum. Homogentisic acid-13C6 can be utilized in research applications involving metabolic tracking and the study of enzymatic pathways related to phenolic acid metabolism. -
Stable Isotope
1-Dodecanol-d25 is a deuterium-labeled form of 1-Dodecanol, a long-chain alcohol that serves as an endogenous metabolite. This stable isotope is primarily utilized in metabolic studies and tracer experiments, allowing for precise tracking of metabolic pathways and interactions in biological systems. Its incorporation into research can enhance the understanding of lipid metabolism and biological processes involving fatty alcohols. -
Stable Isotope
DPPC-13C2 is a stable isotope-labeled form of dipalmitoylphosphatidylcholine (DPPC), a phospholipid that serves as a primary component of pulmonary surfactant. This compound can be utilized to prepare lipid monolayers, bilayers, and liposomes, facilitating various biophysical studies. Additionally, DPPC-liposomes have demonstrated efficacy as a delivery vector, eliciting immune responses against glycosphingolipid antigens in murine models, making it a valuable reagent for research in lipid biochemistry and immunology. -
Stable Isotope
DPPC-d71 is a deuterated form of dimyristoylphosphatidylcholine (DPPC) known for its stable isotope properties. This zwitterionic phosphoglyceride is primarily utilized in the formation of liposomal monolayers, serving as an effective delivery system for targeting glycospingolipid (GSL) antigens. Researchers employ DPPC-d71 in studies involving immunological responses and lipid-based drug delivery mechanisms, enhancing the understanding of membrane interactions and immune activation pathways. -
Stable Isotope
H-HoArg-OH-d4 is a deuterium-labeled form of H-HoArg-OH, which serves as a potent inhibitor of human bone and liver alkaline phosphatase. This stable isotope is valuable for research applications involving enzyme kinetics, metabolic studies, and pharmacokinetic analyses. Its isotopic labeling facilitates precise tracking and quantification in various biological systems. -
Stable Isotope
D-Panthenol-d6 is a deuterium-labeled derivative of D-Panthenol, which serves as a stable isotope. It acts as a biologically active form of pantothenic acid, promoting increased levels of coenzyme A within cells. This reagent is valuable for research applications involving metabolic studies, tracer studies, and quantification of cellular coenzyme A levels. -
Stable Isotope
Adrenosterone-d10 is a deuterium-labeled derivative of Adrenosterone, specifically designed as a stable isotope for advanced research applications. As a competitive inhibitor of 11-beta hydroxysteroid dehydrogenase 1 (HSD11β1), Adrenosterone demonstrates key biological activity by modulating steroid metabolism. This compound exhibits weak androgenic effects and has been studied for its potential in inhibiting metastatic progression in human cancer cells, as well as its role in influencing body composition through fat reduction and muscle mass increase. -
Stable Isotope
Cholestenone-13C is a stable isotope-labeled form of Cholestenone (4-Cholesten-3-one), an intermediate oxidation product of cholesterol primarily metabolized in the liver. This compound exhibits significant mobility within cellular membranes, affecting cholesterol flip-flop dynamics and efflux processes. Cholestenone-13C is valuable for research applications involving lipid metabolism and the role of cholesterol derivatives in cellular functions, providing insights into potential long-term functional defects associated with cholesterol metabolism. -
Stable Isotope
DL-Mevalonolactone-d7 is a deuterium-labeled stable isotope derivative of DL-Mevalonolactone, a key intermediate in the mevalonate pathway. This compound has been shown to decrease mitochondrial membrane potential, reduce NAD(P)H levels, and impair calcium retention in neuronal tissues, ultimately leading to mitochondrial swelling. It is useful for studies involving mitochondrial function, metabolic pathways, and isotopic tracing in biochemical research. -
Stable Isotope
Pyruvic acid-13C2 is a stable isotope-labeled form of pyruvic acid, a crucial intermediate in the metabolic pathways of carbohydrates, proteins, and fats. This reagent facilitates precise metabolic studies and tracer experiments, providing insight into cellular respiration and energy production. It is valuable in biochemical research, particularly in flux analysis and metabolic profiling. -
Stable Isotope
L-Proline-13C5 is a stable isotope-labeled form of the amino acid L-Proline, where five carbon atoms are labeled with carbon-13. L-Proline plays a critical role as a building block of proteins and is involved in collagen synthesis and cellular metabolism. This reagent is essential for isotopic labeling studies, metabolic flux analysis, and tracking biochemical pathways, providing valuable insights into protein synthesis and metabolic activities in various biological systems. -
Stable Isotope
L-Methionine-13C is the stable isotope-labeled form of the essential amino acid L-Methionine. Important for human development, Methionine serves as a crucial building block for protein synthesis and exhibits hepatoprotective properties. This reagent is valuable for metabolic studies, tracing amino acid pathways, and examining the role of Methionine in various biological processes. -
Stable Isotope
3-Hydroxybutyric acid-d4 sodium is a stable isotope-labeled form of 3-Hydroxybutyric acid. This metabolite, known for its elevation in type I diabetes, plays a crucial role in metabolic processes and can influence the properties of membrane lipids. Research applications include metabolic studies, isotope tracing in biochemical pathways, and investigations into the physiological effects of β-Hydroxybutyric acid. -
Stable Isotope
Urea-13C,15N2 is a stable isotope-labeled compound featuring both 13C and 15N isotopes. Urea serves as an effective protein denaturant through direct and indirect mechanisms, demonstrating key biological activity and therapeutic properties, including its role as an emollient and keratolytic agent. It is commonly utilized in research applications, such as evaluating renal function via blood urea nitrogen (BUN) measurements. Additionally, Urea-13C,15N2 is significant in agricultural and chemical industries as a nitrogen source.
