Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Thiamine pyrophosphate-d3 is a deuterated form of thiamine pyrophosphate, serving as a stable isotope. It functions as the active coenzyme of Vitamin B1, playing a critical role as a cofactor in the pyruvate dehydrogenase and α-ketoglutarate dehydrogenase complexes. This compound is essential for studies investigating metabolic pathways, enzymatic activities, and the role of thiamine in cellular metabolism. Its stability as an isotope enhances the accuracy of research applications in metabolic profiling and tracer studies. -
Stable Isotope
L-Threonine-15N is a stable isotope-labeled form of the amino acid L-Threonine. This naturally occurring amino acid is essential for protein synthesis and is produced through microbial fermentation. L-Threonine-15N is utilized in various research applications, including metabolic studies, tracer studies, and protein labeling, providing insights into metabolic pathways and amino acid metabolism. -
Stable Isotope
D-Glucose-d1 is a deuterium-labeled form of D-Glucose, a key monosaccharide involved in energy metabolism and cellular signaling. As a stable isotope, D-Glucose-d1 is utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and biosynthetic pathways. Its application aids researchers in understanding glucose dynamics and its role in various biological processes. -
Stable Isotope
L-Alanine-13C2 is a stable isotope-labeled form of L-Alanine, facilitating precise metabolic studies. As a non-essential amino acid, L-Alanine plays a crucial role in glucose and nitrogen metabolism, supports immune function, and supplies energy to muscle tissues and the central nervous system. This reagent is valuable for applications in metabolic tracing, protein synthesis analysis, and understanding amino acid dynamics in physiological and pathological conditions. -
Stable Isotope
D-Glucose-13C2-4 is a stable isotope-labeled form of D-Glucose, a key monosaccharide involved in multiple biological processes. As a fundamental carbohydrate, D-Glucose plays a crucial role in general metabolism and acts as an essential signaling molecule, influencing cellular metabolic status as well as responses to biotic and abiotic stress. This reagent is particularly useful in metabolic research, enabling the tracing of metabolic pathways and the study of glucose metabolism in various biological contexts. -
Stable Isotope
3-Methyl-2-oxovaleric acid-d8 sodium is a deuterium-labeled derivative of 3-Methyl-2-oxovaleric acid, primarily utilized as a stable isotope. This compound serves as a significant biomarker for mustard airway diseases (MADs) and the formation of uric acid stones, aiding in the investigation of metabolic pathways and disease states. Its applications in research facilitate enhanced understanding of Isoleucine degradation and related metabolic disorders. -
Stable Isotope
L-Cysteine-1-13C is a stable isotope-labeled form of the amino acid L-Cysteine. As a conditionally essential amino acid, L-Cysteine serves as a precursor for key biological molecules including hydrogen sulfide (H2S), glutathione, and taurine. It has been shown to play a role in appetite regulation by suppressing ghrelin levels in both rodent and human studies, making it valuable for various research applications, particularly in metabolic and nutritional studies. -
Stable Isotope
4,6-Dioxoheptanoic acid-13C5 is a stable isotope-labeled variant of 4,6-Dioxoheptanoic acid, a potent inhibitor of heme biosynthesis. This compound is utilized in metabolic studies and tracer experiments to investigate biosynthetic pathways involving heme. Its isotopic labeling enables precise tracking and quantification in various biological contexts. -
Stable Isotope
L-Tyrosine-d3 is a deuterium-labeled derivative of the non-essential amino acid L-Tyrosine. It serves as a stable isotope for biochemical studies, enabling researchers to trace metabolic pathways and analyze protein synthesis. L-Tyrosine is known to affect various biological processes, including the inhibition of citrate synthase activity in the posterior cortex, making L-Tyrosine-d3 valuable for neurobiological and metabolic research applications. -
Stable Isotope
L-Tyrosine-d7 is a deuterium-labeled form of the amino acid L-Tyrosine, which serves as a stable isotope for research applications. This non-essential amino acid plays a role in inhibiting citrate synthase activity, particularly in the posterior cortex. L-Tyrosine-d7 is valuable for studies involving metabolic pathways and tracer studies in isotope labeling experiments. Its unique isotopic signature enables precise quantification and tracing of L-Tyrosine metabolism in biological systems. -
Stable Isotope
Myristic acid-d5 is a deuterium-labeled form of myristic acid, a saturated fatty acid composed of 14 carbon atoms. This stable isotope is used extensively in metabolic studies and lipid research, providing a valuable tool for tracing and quantifying fatty acid metabolism. Myristic acid-d5 can aid in elucidating the roles of dietary fats and the biochemical pathways they influence in various biological systems. -
Stable Isotope
D-Galactose-13C is a stable isotope-labeled form of D-Galactose, a natural aldohexose and C-4 epimer of glucose. This reagent is utilized in metabolic studies to trace the pathways of carbohydrate metabolism and assess galactose's role in various biological systems. D-Galactose-13C is particularly valuable in isotopic labeling experiments and NMR studies, enhancing the understanding of metabolic flux in living organisms. -
Stable Isotope
L-Isoleucine-1-13C is a stable isotope-labeled form of the essential amino acid L-Isoleucine. This nonpolar hydrophobic amino acid plays a critical role in protein synthesis and cellular metabolism. L-Isoleucine-1-13C is valuable for tracer studies in metabolic research, allowing for insights into amino acid metabolism and protein turnover in various biological systems. -
Stable Isotope
D-Erythro-dihydrosphingosine-d7 is a deuterium-labeled variant of D-Erythro-dihydrosphingosine, functioning primarily as a stable isotope. This compound serves as a specific inhibitor of cytosolic phospholipase A2α (cPLA2α), allowing for the investigation of lipid metabolism and signaling pathways. Its application is essential in research focused on membrane biology, inflammation, and related metabolic disorders. -
Stable Isotope
Monoolein-d5 is a deuterium-labeled derivative of Monoolein, serving as a stable isotope. This compound is utilized in metabolic studies, particularly in tracing lipid metabolism and evaluating lipid-related pathways. Its unique isotopic labeling enables precise quantification and characterization in various biological research applications, including drug formulation and development. -
Stable Isotope
Vanillin-13C6 is a stable isotope-labeled form of vanillin, specifically enriched with six carbon-13 nuclei. This compound is commonly utilized in metabolic studies, allowing researchers to trace the pathways and fates of vanillin in biological systems. Its distinctive aroma and flavor profile make it an important reagent in food science, perfumery, and pharmaceutical research. Vanillin-13C6 serves as a valuable tool for understanding metabolic processes and interactions involving vanillin. -
Stable Isotope
Cholesteryl oleate-d7 is a deuterium-labeled derivative of cholesteryl oleate, a lipid ester synthesized from cholesterol and oleic acid. This stable isotope serves as a valuable tool for studying lipid transport, storage, and cell membrane dynamics in biological systems. Additionally, cholesteryl oleate has potential applications as a biomarker for prostate cancer and can be utilized in the preparation of cationic solid lipid nanoparticles (SLNs) for enhanced gene silencing efficiency. -
Stable Isotope
16α-Hydroxydehydroepiandrosterone-d6 is a stable isotope-labeled derivative of 16α-Hydroxydehydroepiandrosterone (16α-Hydroxy-DHEA). This compound is utilized in pharmacokinetic studies and metabolic profiling to trace and quantify endogenous DHEA metabolites in biological samples. The deuterium labeling enhances sensitivity in mass spectrometry applications, making it essential for rigorous analytical research in endocrinology and steroid biosynthesis. -
Stable Isotope
L-Carnosine-d4 is the deuterated form of L-Carnosine, a dipeptide composed of beta-alanine and histidine. This stable isotope has been utilized in research to study the biochemical effects of L-Carnosine, particularly its potential in mitigating age-related changes. Applications include metabolic studies and the investigation of antioxidant properties associated with L-Carnosine's role in cellular aging processes. -
Stable Isotope
L-Methionine-13C,d5 is a stable isotope-labeled form of the essential amino acid L-Methionine, featuring both carbon-13 and deuterium isotopes. This compound serves as a hepatoprotectant and is essential for various biological processes, including protein synthesis and methylation reactions. L-Methionine-13C,d5 is widely used in metabolic studies, tracer experiments, and research on amino acid metabolism, providing insights into physiological pathways and nutrient utilization. -
Stable Isotope
Diethyl phosphate-d10-1 is a stable isotope-labeled derivative of diethyl phosphate, classified as an organophosphorus pesticide metabolite. This compound has been shown to modulate thyroid hormone-related processes and influence gut microbiota in rat models. It serves as a valuable tool for biochemical research, particularly in studies investigating the metabolism and ecological effects of organophosphates. -
Stable Isotope
Mono-(2-ethylhexyl) phthalate-d4 is a deuterium-labeled derivative of Mono-(2-ethylhexyl) phthalate, primarily utilized as a stable isotope in research. This compound acts as a significant bioactive metabolite of diethylhexyl phthalate (DEHP) and is known to influence fatty acid synthesis in hepatocytes through the regulation of gene and protein expression. Its application is particularly relevant in studies investigating non-alcoholic fatty liver disease (NAFLD) and other metabolic disorders. -
Stable Isotope
Sodium 3-Methyl-2-oxobutanoic acid-13C2 is a stable isotope-labeled compound, specifically the 13C variant of Sodium 3-methyl-2-oxobutanoate. This compound serves as a crucial precursor for the biosynthesis of pantothenic acid in Escherichia coli, making it valuable for metabolic studies and tracer experiments. Its use in tracing metabolic pathways and understanding vitamin synthesis in microbial systems is essential for research in nutritional biochemistry and microbiology. -
Stable Isotope
4-Aminobenzoic acid-d4 is a deuterium-labeled derivative of 4-Aminobenzoic acid, serving as a stable isotope in research applications. This compound is a critical intermediate in the biosynthesis of folate in microorganisms, including bacteria, plants, and fungi. Its isotopic labeling enables precise tracking of metabolic pathways and enhances studies involving folate synthesis and utilization. -
Stable Isotope
Anserine-d4 is a deuterated form of Anserine, a naturally occurring dipeptide composed of histidine and β-alanine. This stable isotope is utilized as a biochemical tracer in metabolic studies and research involving histidine-containing compounds. Anserine exhibits various biological activities, including antioxidant properties, buffering capacity, and anti-glycation effects. Additionally, it has been shown to enhance cognitive functions in Alzheimer's disease models, making it relevant for neurobiological research. -
Stable Isotope
DL-Tryptophan-d3 is a deuterium-labeled derivative of DL-Tryptophan, an essential amino acid and endogenous metabolite. This stable isotope is primarily utilized in metabolic studies and can aid in tracking metabolic pathways in biological research. Its incorporation in tracer studies facilitates the investigation of tryptophan metabolism and its associated biological effects. -
Stable Isotope
Arachidic acid-d4 is a deuterium-labeled variant of arachidic acid, a long-chain saturated fatty acid with significant biological relevance. This stable isotope is utilized in metabolic studies to trace lipid metabolism and investigate the incorporation of fatty acids into biological systems. Furthermore, arachidic acid-d4 conjugated with chitosan oligosaccharides presents potential for research in drug delivery systems, particularly in anti-cancer applications. -
Stable Isotope
2'-Deoxyuridine-13C,15N2 is a stable isotope-labeled derivative of 2'-deoxyuridine, featuring carbon-13 and nitrogen-15 isotopes. This compound has been shown to induce chromosome breakage and decrease thymidylate synthase activity, making it relevant for studies on nucleotide metabolism and DNA synthesis. 2'-Deoxyuridine serves as a precursor in the synthesis of Edoxudine, thus providing utility in research focused on antiviral agents and nucleoside analogs. -
Stable Isotope
L-Hydroxyproline-d4 is a deuterated derivative of L-Hydroxyproline, a naturally occurring amino acid and an isomer of hydroxyproline. This stable isotope serves as a valuable chiral building block in pharmaceutical synthesis and metabolic studies. It is particularly useful in applications requiring isotopic labeling for NMR spectroscopy and other analytical techniques in chemical research. -
Stable Isotope
Cholesterol-d1 is a deuterated form of cholesterol, serving as a stable isotope for biochemical research. As a principal sterol in mammals, cholesterol constitutes 20-25% of the structural components of plasma membranes, influencing their fluidity and permeability. This compound is essential for studying membrane dynamics and the functionality of transporters and signaling proteins. Additionally, cholesterol acts as an endogenous agonist for estrogen-related receptor α (ERRα), making it relevant for research in cellular signaling and hormonal regulation. -
Stable Isotope
Glycerol-13C2 is a stable isotope-labeled form of glycerol, designed for applications in metabolic studies and tracer experiments. This compound serves as a critical reagent in sample preparation and enhances gel formation for polyacrylamide gel electrophoresis. Its isotopic labeling allows for detailed analysis of metabolic pathways and dynamics in various biological systems. -
Stable Isotope
Estradiol-d2 is a deuterium-labeled derivative of estradiol, a steroid sex hormone essential for regulating fertility and secondary sexual characteristics in females. This compound acts primarily through the estrogen receptor β (ERβ) pathway, where it upregulates IL-6 expression. Estradiol-d2 serves as a valuable stable isotope for metabolic and pharmacokinetic studies, enabling researchers to investigate estradiol's physiological roles and interactions in cellular and biological systems. -
Stable Isotope
Estriol-d3 is a deuterium-labeled analog of estriol, functioning as a stable isotope. It serves as a useful tool for elucidating the biochemical mechanisms of estrogen receptor signaling, particularly in estrogen receptor-negative breast cancer cells, where it acts as an antagonist. This compound is valuable in research applications involving hormone metabolism and signaling pathways in cancer biology. -
Stable Isotope
Tetradecanedioic acid-d24 is a deuterium-labeled form of tetradecanedioic acid, an endogenous metabolite classified as a long-chain fatty acid. This stable isotope can serve as a valuable tool in metabolic studies and the investigation of organic anion-transporting polypeptide interactions. Its application in research facilitates the understanding of biomarker dynamics and transport mechanisms in various biological contexts. -
Stable Isotope
Lignoceric acid-d4-2 is a deuterium-labeled derivative of Lignoceric acid, a saturated fatty acid with a carbon chain length of 24 (C24:0). This compound is primarily synthesized in the developing brain and serves as a by-product of lignin metabolism. Lignoceric acid-d4-2 is valuable for research focused on neurodevelopmental disorders, including Zellweger syndrome and adrenoleukodystrophy, providing insights into metabolic pathways and lipid profiling in these conditions. -
Stable Isotope
Benzyl alcohol-d5 is a deuterium-labeled derivative of benzyl alcohol, serving as a stable isotope for various research applications. This aromatic alcohol is commonly utilized as an internal standard in mass spectrometry, enabling precise quantification in metabolic studies and chemical analysis. Its unique mass provides valuable insights in tracer studies, making it an essential reagent for researchers investigating the metabolic pathways of aromatic compounds. -
Stable Isotope
7α-Hydroxy-4-cholesten-3-one-d7 is a deuterium-labeled analogue of 7α-Hydroxy-4-cholesten-3-one, which serves as an intermediate in bile acid synthesis from cholesterol. This compound acts as an agonist for the pregnane X receptor (PXR) and is recognized as a biomarker for bile acid loss, irritable bowel syndrome, and various conditions linked to impaired bile acid biosynthesis. Additionally, 7α-Hydroxy-4-cholesten-3-one is a physiological substrate for the enzyme CYP8B1, making it valuable for research in metabolic and gastrointestinal disorders. -
Stable Isotope
Biotin-d2-1 is a deuterium-labeled form of Biotin, an essential enzyme co-factor found in nearly all living cells. This stable isotope labeled compound provides valuable insights into metabolic pathways and biotin-dependent enzyme activities. It is widely used in biochemical research, including studies on protein interactions, cellular metabolism, and vitamin B7 biology. -
Stable Isotope
5α-Cholestan-3β-ol-d5 is a deuterated derivative of 5α-Cholestan-3β-ol, a steroid compound. As a stable isotope, this reagent is essential for applications in metabolic studies and tracer experiments. It is utilized in research involving lipid metabolism, steroid biosynthesis, and structural biology investigations, providing valuable insights into biological processes. -
Stable Isotope
2-Phenylglycine-d5 is a deuterated derivative of 2-Phenylglycine, serving as a stable isotope for various analytical applications. This compound is involved in metabolic studies, particularly in the context of human breast milk composition during the early lactation phase (W2 to W4). It is valuable for research analyzing metabolic pathways and tracing studies in nutritional science. -
Stable Isotope
L-Leucine-d7 is a stable isotope-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) that plays a critical role in protein synthesis. By activating the mTOR signaling pathway, L-Leucine-d7 can be utilized in metabolic studies, tracer applications, and protein turnover research. This deuterated variant allows for precise tracking and analysis in various biological systems, enhancing the understanding of amino acid metabolism and its implications in health and disease. -
Stable Isotope
D-Alanine-d4 is a deuterium-labeled derivative of D-Alanine, primarily utilized as a stable isotope in chemical research. This compound serves as a weak agonist of the glycine receptor (GlyR), demonstrating an EC50 value of 9 mM. It is valuable for studies involving neurotransmission modulation, metabolic pathways, and isotope-labeling techniques in biochemical assays. -
Stable Isotope
L-Homocystine-d8 is a deuterium-labeled derivative of L-homocystine, representing the oxidized form of L-homocysteine. It serves as a stable isotope that facilitates the investigation of cardiovascular disease mechanisms, particularly in the context of homocysteine, which is implicated as a pro-thrombotic factor, an agent that impairs vasodilation, and a pro-inflammatory mediator. This compound is useful in studies examining endoplasmic reticulum stress and its contribution to various cardiovascular conditions. -
Stable Isotope
Indole-d6 is a deuterium-labeled isotope of indole, serving as a stable isotope for various biological studies. This compound is used extensively in metabolomics and pharmacokinetic research to trace metabolic pathways and analyze the behavior of indole and its derivatives within biological systems. Its incorporation into experiments aids in enhancing the accuracy of mass spectrometry and NMR spectroscopy analyses. -
Stable Isotope
Cytidine 5′-monophosphate-13C9,15N3 dilithium is a stable isotope-labeled derivative of cytidine 5'-monophosphate, containing both carbon-13 and nitrogen-15 isotopes. This nucleotide serves as a fundamental monomer in RNA synthesis, featuring a nucleobase (cytosine), a pentose sugar (ribose), and a phosphate group. The incorporation of stable isotopes in research applications facilitates studies in metabolic pathways, nucleic acid dynamics, and RNA-related biochemical processes, providing valuable insights into cellular mechanisms and functions. -
Stable Isotope
Stearic acid-d4 is a deuterated analogue of stearic acid, serving as a stable isotope labeling agent. This long-chain saturated fatty acid is commonly found in various animal and vegetable fats and oils. Stearic acid-d4 is utilized in metabolic studies, fatty acid profiling, and tracing lipid metabolism, providing valuable insights into biological processes involving fatty acids. -
Stable Isotope
L-Alanine-13C,d is a stable isotope-labeled form of L-Alanine, a non-essential amino acid that plays a critical role in protein synthesis, sugar metabolism, and immune function. The presence of 13C and deuterium allows for precise metabolic and kinetic studies in biological systems. This reagent is valuable in applications such as metabolic tracing, NMR spectroscopy, and understanding amino acid metabolism in various physiological contexts. -
Stable Isotope
Ercalcidiol-d3 is a deuterated form of Ercalcidiol, a biologically active metabolite of Vitamin D2. This stable isotope serves as a valuable indicator for assessing Vitamin D status in various biological samples. Its unique properties facilitate research in vitamin D metabolism, pharmacokinetics, and related health studies. Ercalcidiol-d3 is an essential tool for scientists investigating the role of Vitamin D in health and disease. -
Stable Isotope
Riboflavin-13C4,15N2 is a stable isotope-labeled form of riboflavin, incorporating four carbon-13 and two nitrogen-15 isotopes. This micronutrient is essential for various biological processes, including energy metabolism and cellular function. Riboflavin-13C4,15N2 is utilized in metabolic studies, tracer applications, and nutritional research to investigate vitamin B2 metabolism and its physiological effects in both human and animal models. -
Stable Isotope
2,3-Butanediol-d8 is a deuterated form of 2,3-Butanediol, a microbially derived compound. This stable isotope serves as a discriminating urinary biomarker specifically for Fmo5-/- mice. In addition to its use in metabolic studies, 2,3-Butanediol-d8 is known to inhibit age-related increases in plasma cholesterol levels. Its potential applications extend to various industries, including the formulation of printing inks, perfumes, and pharmaceutical carriers.
