J1038 is a selective inhibitor of histone deacetylase 8 (HDAC8), targeting the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8). This compound demonstrates significant inhibition of HDAC8 activity, making it a valuable tool for studying epigenetic regulation and potential therapeutic applications in cancer and neurodegenerative diseases. Researchers can utilize J1038 to explore the biological effects of HDAC8 inhibition in various cellular contexts.
J1038 is a selective inhibitor of histone deacetylase 8 (HDAC8), targeting the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8). This compound demonstrates significant inhibition of HDAC8 activity, making it a valuable tool for studying epigenetic regulation and potential therapeutic applications in cancer and neurodegenerative diseases. Researchers can utilize J1038 to explore the biological effects of HDAC8 inhibition in various cellular contexts.
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