JAK1-IN-11

Name: JAK1-IN-11
Brand: Adooq Bioscience
SKU: A33264
Rating: 5 (288 reviews)

Catalog No.: A33264

JAK1 Inhibitor

JAK1-IN-11 is a selective inhibitor of Janus kinase 1 (JAK1) with an IC50 of 0.02 nM, demonstrating strong potency. It also exhibits inhibitory activity against JAK2 with an IC50 of 0.44 nM. Due to its high selectivity for JAK1, JAK1-IN-11 is an essential tool for investigating JAK-dependent signaling pathways and exploring therapeutic strategies in various inflammatory and autoimmune diseases.

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Grouped product items
Size	Price	Stock
1mg	$400.00	In stock
5mg	$960.00	In stock
10mg	$1,680.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	JAK1-IN-11 is a selective inhibitor of Janus kinase 1 (JAK1) with an IC50 of 0.02 nM, demonstrating strong potency. It also exhibits inhibitory activity against JAK2 with an IC50 of 0.44 nM. Due to its high selectivity for JAK1, JAK1-IN-11 is an essential tool for investigating JAK-dependent signaling pathways and exploring therapeutic strategies in various inflammatory and autoimmune diseases.

Product Information

Catalog Num	A33264
Formula	C26H36N6O4S
Molecular Weight	528.67
CAS Number	2427608-43-1
SMILES	C[C@@H](O)C1=NC2=CNC3=NC=CC3=C2N1N(CC4)CCC4CNS(C[C@@]56C(C)(C)[C@@](CC6)([H])CC5=O)(=O)=O

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