JH-LPH-33 is a sulfonyl piperazine analog that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). It exhibits significant antibiotic activity, demonstrating a minimum inhibitory concentration (MIC) of 0.66 μg/mL. This compound is relevant for research applications focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies.
JH-LPH-33 is a sulfonyl piperazine analog that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). It exhibits significant antibiotic activity, demonstrating a minimum inhibitory concentration (MIC) of 0.66 μg/mL. This compound is relevant for research applications focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies.
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