JNJ-26481585 (Quisinostat)

Catalog No.: A10492

HDAC inhibitor

JNJ-26481585 (Quisinostat)

JNJ-26481585 (Quisinostat) Chemical Structure

CAS NO. 875320-29-9

JNJ-26481585 (Quisinostat) is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$200.00
50 mg
$400.00
100 mg
$620.00
10mM * 1mL in DMSO
$120.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Minoru Ueda, .et al. The Distinct Roles of Class I and II RPD3-Like Histone Deacetylases in Salinity Stress Response, Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096

Biological Activity

JNJ-26481585 (Quisinostat) is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).
In vitro (25°C) DMSO 79 mg/mL (200.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.74 mL 253.49 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10492
Actions Inhibitor
M. Wt 394.5
Formula C21H26N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 875320-29-9
Synonyms JNJ26481585
SMILES CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO

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