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hERG1 potassium channel activator

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Catalog No. A15493

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KB130015 2mg A15493-2
KB130015 5mg A15493-5

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KB130015 is a novel activator of hERG1 potassium channels, blocking native and recombinant hERG1 channels at high voltages, but activating them at low voltages.


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Chemical Information

Catalog Num A15493
Actions Activator
M. Wt 548.11
Formula C18H14I2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 147030-48-6
Synonyms KB 130015, KB-130015
SMILES code CC1=C(C2=CC=CC=C2O1)CC3=CC(=C(C(=C3)I)OCC(=O)O)I
Chemical Name 2-[2,6-diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenoxy]acetic acid

Biological Activity

KB130015 is a novel activator of hERG1 potassium channels, blocking native and recombinant hERG1 channels at high voltages, but activating them at low voltages.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.24 mL 91.22 mL 182.45mL
0.5 mM 3.65 mL 18.24 mL 36.49 mL
1 mM 1.82 mL 9.12 mL 18.24 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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