KH-259 is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 0.26 μM. This compound demonstrates noteworthy antidepressant effects in murine models by targeting HDAC6 within the central nervous system. KH-259 is valuable for research related to neurodegenerative diseases and the development of therapeutic strategies targeting epigenetic regulation.
KH-259 is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 0.26 μM. This compound demonstrates noteworthy antidepressant effects in murine models by targeting HDAC6 within the central nervous system. KH-259 is valuable for research related to neurodegenerative diseases and the development of therapeutic strategies targeting epigenetic regulation.
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