KN-93 Phosphate

Catalog No.: A14288

CaMKII inhibitor

KN-93 Phosphate

KN-93 Phosphate Chemical Structure

CAS NO. 1188890-41-6

KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $110.00

Special Price $99.00

25 mg

Regular Price: $220.00

Special Price $198.00

50 mg

Regular Price: $400.00

Special Price $360.00

10mM * 1mL in DMSO

Regular Price: $125.00

Special Price $112.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.
Targets
CaMKII
0.37 μM(Ki)
In vitro DMSO 100 mg/mL (166.93 mM)
Water 92 mg/mL (153.58 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.69 mL 83.47 mL 166.94 mL
0.5 mM 3.34 mL 16.69 mL 33.39 mL
1 mM 1.67 mL 8.35 mL 16.69 mL
5 mM 0.33 mL 1.67 mL 3.34 mL

*The above data is based on the productmolecular weight 599.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14288
Actions Inhibitor
M. Wt 599.03
Formula C26H29ClN2O4S. H3O4P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1188890-41-6
Synonyms KN93, KN 93
SMILES [HH].CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OOP(=O)=O

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