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- Kazuki Yuasa,et al. Targeted ablation of p38汐 MAPK suppresses denervation-induced muscle atrophy, Sci Rep, 2018, 8: 9037 29899565
|Storage||at -20°C 3 years Powder|
|Synonyms||KN93, KN 93|
|Chemical Name||Benzenesulfonamide, N-?[2-?[[[(2E)?-?3-?(4-?chlorophenyl)?-?2-?propen-?1-?yl]?methylamino]?methyl]?phenyl]?-?N-?(2-?hydroxyethyl)?-?4-?methoxy-?, phosphate (1:1)|
|KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.|
|Solubility (25°C)*||In vitro||DMSO||100 mg/mL (166.93 mM)|
|Water||92 mg/mL (153.58 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||16.69 mL||83.47 mL||166.94mL|
|0.5 mM||3.34 mL||16.69 mL||33.39 mL|
|1 mM||1.67 mL||8.35 mL||16.69 mL|
|5 mM||0.33 mL||1.67 mL||3.34 mL|
*The above data is based on the productmolecular weight 599.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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