Ko-143

Catalog No.: A11475

BCRP inhibitor

Ko-143

Ko-143 Chemical Structure

CAS NO. 461054-93-3

Ko 143 is potent and selective inhibitor of breast cancer resistance protein multidrug transporter (BCRP) with an EC90 value of 26 nM.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
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Biological Activity

Ko 143 is potent and selective inhibitor of breast cancer resistance protein multidrug transporter (BCRP) with an EC90 value of 26 nM.
In vitro DMSO 89 mg/mL (189.53 mM)
Water Insoluble
Ethanol 89 mg/mL (189.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.48 mL 212.95 mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11475
Actions Inhibitor
CAS No. 461054-93-3
Formula C26H35N3O5
M. Wt 469.59
Purity >98%
Synonyms Ko 143,Ko143
SMILES O=C1N2[[email protected]@H](CC(C)C)C(NC3=C4C=CC(OC)=C3)=C4C[[email protected]@H]2C(N[[email protected]@H]1CCC(OC(C)(C)C)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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