KTT-1 is a kinetically selective and orally bioavailable inhibitor of HDAC2, demonstrating significant selectivity over HDAC1. This compound effectively inhibits osteoclast differentiation by downregulating c-Fos expression. In preclinical models, KTT-1 has shown efficacy in suppressing symptoms of arthritis, particularly in the collagen-induced arthritis (CIA) mouse model. KTT-1 is suitable for research applications related to rheumatoid arthritis and neurodegenerative diseases.
KTT-1 is a kinetically selective and orally bioavailable inhibitor of HDAC2, demonstrating significant selectivity over HDAC1. This compound effectively inhibits osteoclast differentiation by downregulating c-Fos expression. In preclinical models, KTT-1 has shown efficacy in suppressing symptoms of arthritis, particularly in the collagen-induced arthritis (CIA) mouse model. KTT-1 is suitable for research applications related to rheumatoid arthritis and neurodegenerative diseases.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
