KU-55933

Catalog No.: A10506

ATM inhibitor

KU-55933

KU-55933 Chemical Structure

CAS NO. 587871-26-9

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $32.00

10 mg

Regular Price: $60.00

Special Price $48.00

50 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
Targets
Target Value
ATMIC50: 12.9nM
DNA-PKIC50: 2.5μM
mTORIC50: 9.3μM
PI3KIC50: 16.6μM
ATRIC50: >100μM
PI4KIC50: >100μM
In vitro (25°C) DMSO 33 mg/mL (83.44 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 5% DMSO and 47.5% PEG300 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.28 mL 126.42 mL 252.84 mL
0.5 mM 5.06 mL 25.28 mL 50.57 mL
1 mM 2.53 mL 12.64 mL 25.28 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10506
Actions Inhibitor
M. Wt 395.5
Formula C21H17NO3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 587871-26-9
Synonyms KU55933
SMILES C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy KU-55933 | KU-55933 Supplier | purchase KU-55933 | KU-55933 cost | KU-55933 manufacturer | order KU-55933 | KU-55933 distributor | buy 587871-26-9| 587871-26-9 Supplier | purchase 587871-26-9 | 587871-26-9 cost | 587871-26-9 manufacturer | order 587871-26-9 | 587871-26-9 distributor
Rewards