Trusted by 10,000+ Scientists since 2006



ATM inhibitor

0 Customer Reviews
Catalog No. A10506

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KU-55933 5mg A10506-5

Regular Price: €38.00

Special Price: €34.20

KU-55933 10mg A10506-10

Regular Price: €57.00

Special Price: €51.30

KU-55933 50mg A10506-50

Regular Price: €190.00

Special Price: €171.00

KU-55933 100mg A10506-100

Regular Price: €332.50

Special Price: €299.25

KU-55933 10mM * 1mL in DMSO A10506-10mM-D

Regular Price: €57.00

Special Price: €51.30

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.


Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
KU-55933 Citations (2)
  • Hayakawa K, .et al. Planar compression of extracellular substrates induces S phase arrest via ATM-independent CHK2 activation, Biochem Biophys Res Commun, 2018, Dec 2;506(4):983-989 PMID: 30404732
  • Chwastek J, .et al. The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D, Int J Biochem Cell Biol, 2017, Jun;87:38-53 PMID: 28341201

Chemical Information

Catalog Num A10506
Actions Inhibitor
M. Wt 395.5
Formula C21H17NO3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 587871-26-9
Synonyms KU55933

Biological Activity

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
Target Value
ATMIC50: 12.9nM
DNA-PKIC50: 2.5μM
mTORIC50: 9.3μM
PI3KIC50: 16.6μM
ATRIC50: >100μM
PI4KIC50: >100μM


Solubility (25°C) * In vitro DMSO 33 mg/mL (83.44 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 5% DMSO and 47.5% PEG300 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.28 mL 126.42 mL 252.84mL
0.5 mM 5.06 mL 25.28 mL 50.57 mL
1 mM 2.53 mL 12.64 mL 25.28 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Keywords:buy KU-55933 | KU-55933 Supplier | purchase KU-55933 | KU-55933 cost | KU-55933 manufacturer | order KU-55933 | KU-55933 distributor | buy 587871-26-9| 587871-26-9 Supplier | purchase 587871-26-9 | 587871-26-9 cost | 587871-26-9 manufacturer | order 587871-26-9 | 587871-26-9 distributor